Patents by Inventor Koichi Beppu

Koichi Beppu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperidine derivatives as substance P antagonists
    Patent number: 5886011
    Abstract: Piperidine derivatives represented by general formula (I) ##STR1## or pharmaceutically acceptable acid addition salts thereof: wherein n represents an integer of 0 or 1; X represents CH.sub.2, O or CH--CH.sub.3 ; R represents hydrogen, halogen, lower alkyl, hydroxy, lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, substituted aminosulfonyl or nitro; R.sub.1 and R.sub.2 may be the same or different and each represents hydrogen or lower alkyl, are disclosed. The piperidine derivatives have an antagonism on Substance P and is useful as a preventive or remedy for asthma, vomiting, etc.
    Type: Grant
    Filed: September 26, 1997
    Date of Patent: March 23, 1999
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Yoshihiro Tanoue, Koichi Beppu, Akira Okayama, Osami Sakamoto
  • Phenylalkanoic acid derivatives, process for producing the same and process for separating optical isomers thereof
    Patent number: 5434292
    Abstract: A novel phenylalkanoic acid derivative represented by the following formula ##STR1## wherein n is an integer of 1-2, X is a halogen atom, alkoxyl group or nitro group, R is a hydrogen atom or alkyl group, and Z is a hydrogen atom or acyl group,a method for producing said derivative, a method for separating the optical isomers of said derivative from each other, as well as an anti-inflammatory drug, analgesic drug or preparation for external use each containing said derivative.
    Type: Grant
    Filed: February 4, 1994
    Date of Patent: July 18, 1995
    Assignee: Hisamitsu Pharmaceutical Co., Inc.
    Inventors: Masaru Saita, Hisataka Inoue, Koichi Beppu, Terumi Hachiya, Ikuo Shinohara, Yasuaki Taniguchi, Yoshiki Deguchi, Yoshihiro Hamaguchi