Abstract: Provided is a cancer treatment or prevention technique that molecularly targets GD2. A GD2-binding molecule includes a heavy-chain variable region containing a heavy-chain CDR1 containing the amino acid sequence represented by SEQ ID NO: 1, a heavy-chain CDR2 containing the amino acid sequence represented by SEQ ID NO: 2, and a heavy-chain CDR3 containing the amino acid sequence represented by SEQ ID NO: 3, and/or a light-chain variable region containing a light-chain CDR1 containing the amino acid sequence represented by SEQ ID NO: 9, a light-chain CDR2 containing the amino acid sequence represented by SEQ ID NO: 10, and a light-chain CDR3 containing the amino acid sequence represented by SEQ ID NO: 11.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: A composition having tissue repair activity, which is capable of promoting reactions associated with tissue repair, contains at least one selected from the group consisting of a first component that is a protein having a monocyte chemotactic protein-1 (MCP-1) activity, a second component that is a protein having the extracellular domain activity of sialic acid-binding immunoglobulin-type lectin-9 (Siglec-9), and a third component that is at least one of chondroitin sulfate and chondroitin sulfate proteoglycan.

Abstract: The object of the present invention is to provide ?1,4-galactosyltransferase to transfer a galactose residue to C4 position of galactose residue of lactosylceramide or galactosylceramide, and DNA coding for the enzyme. What is provided includes the following polypeptides (a) and (b), and DNAs encoding thereof: (a) a polypeptide consisting of an amino acid sequence represented by the amino acid Nos. 46-353 in SEQ ID NO: 2; or (b) a polypeptide which comprises an amino acid sequence including substitution, deletion, insertion or transposition of one or few amino acids in the amino acid sequence of (a) and which has an enzymatic activity to transfer a galactose residue from a galactose donor to C4 position of galactose residue of lactosylceramide or galactosylceramide which serves as an acceptor.

Abstract: In controlling a seat belt retractor, at least one of signals selected from a state signal showing a movement of an occupant wearing a seat belt and an external signal obtained from detecting means installed in a vehicle during running thereof is received. Then, a rotational torque of a motor is selected to a predetermined reduction ratio corresponding to at least one of the state signal and the external signal from a plurality of torques. The motor is controlled to a predetermined torque, to thereby wind the webbing on the spool.

Abstract: The object of the present invention is to provide ?1,4-galactosyltransferase to transfer a galactose residue to C4 position of galactose residue of lactosylceramide or galactosylceramide, and DNA coding for the enzyme. What is provided includes the following polypeptides (a) and (b), and DNAs encoding thereof: (a) a polypeptide consisting of an amino acid sequence represented by the amino acid Nos. 46-353 in SEQ ID NO: 2; or (b) a polypeptide which comprises an amino acid sequence including substitution, deletion, insertion or transposition of one or few amino acids in the amino acid sequence of (a) and which has an enzymatic activity to transfer a galactose residue from a galactose donor to C4 position of galactose residue of lactosylceramide or galactosylceramide which serves as an acceptor.

Abstract: In controlling a seat belt retractor, at least one of signals selected from a state signal showing a movement of an occupant wearing a seat belt and an external signal obtained from detecting means installed in a vehicle during running thereof is received. Then, a rotation of a spool for a webbing is controlled by switching a rotational torque of a motor to a predetermined reduction ratio corresponding to at least one of the state signal and the external signal, or a driving state of the motor is controlled to a predetermined torque, to thereby wind the webbing on the spool. After fastening the seat belt, the seat belt is automatically wound, and after a predetermined time from completion of winding of the webbing, it is determined whether the winding of the webbing is further needed, and if necessary, the webbing is wound again.

Abstract: The object of the present invention is to provide &agr;1,4-galactosyltransferase to transfer a galactose residue to C4 position of galactose residue of lactosylceramide or galactosylceramide, and DNA coding for the enzyme. What is provided includes the following polypeptides (a) and (b), and DNAs encoding thereof: (a) a polypeptide consisting of an amino acid sequence represented by the amino acid Nos. 46-353 in SEQ ID NO: 2; or (b) a polypeptide which comprises an amino acid sequence including substitution, deletion, insertion or transposition of one or few amino acids in the amino acid sequence of (a) and which has an enzymatic activity to transfer a galactose residue from a galactose donor to C4 position of galactose residue of lactosylceramide or galactosylceramide which serves as an acceptor.

Abstract: A seat belt retractor includes a base frame, a spool having a spool shaft journalled to the base frame, a webbing wound around the spool, a return spring connected to the spool for winding the webbing by a return force thereof, a motor connected to the spool for winding the spool, and a speed-reduction mechanism interposed between the motor and the spool. The speed-reduction mechanism winds the webbing at a low speed for fitting the webbing to an occupant, and includes a contrate gear with a predetermined reduction gear ratio. Thus, the webbing is wound by operation of the motor via the contrate gear.

Abstract: A seat belt retractor includes a base frame, a spool journalled to the base frame, a webbing wound around the spool, and a motor for rotating the spool. A speed-reduction mechanism is interposed between the motor and the spool. The speed-reduction mechanism includes at least one transmission train with a predetermined gear ratio, a common transmission element connected to the transmission train, and a resistant torque device connected to the transmission train. The common transmission element transmits rotation of the motor to the spool when the torque of the rotation is smaller than the preset value. Winding of the webbing is made based on the wearing condition of the webbing and the running condition of the vehicle.

Abstract: A seat belt retractor includes a base frame, a spool having a spool shaft journalled to the base frame, a webbing wound around the spool, a return spring connected to the spool for winding the webbing by a return force thereof, a motor connected to the spool for winding the spool, and a speed-reduction mechanism interposed between the motor and the spool. The speed-reduction mechanism winds the webbing at a low speed for fitting the webbing to an occupant, and includes a contrate gear with a predetermined reduction gear ratio. Thus, the webbing is wound by operation of the motor via the contrate gear.

Abstract: In controlling a seat belt retractor, at least one of signals selected from a state signal showing a movement of an occupant wearing a seat belt and an external signal obtained from detecting means installed in a vehicle during running thereof is received. Then, a rotation of a spool for a webbing is controlled by switching a rotational torque of a motor to a predetermined reduction ratio corresponding to at least one of the state signal and the external signal, or a driving state of the motor is controlled to a predetermined torque, to thereby wind the webbing on the spool.

Abstract: In controlling a seat belt retractor, at least one of signals selected from a state signal showing a movement of an occupant wearing a seat belt and an external signal obtained from detecting means installed in a vehicle during running thereof is received. Then, a rotation of a spool for a webbing is controlled by switching a rotational torque of a motor to a predetermined reduction ratio corresponding to at least one of the state signal and the external signal, or a driving state of the motor is controlled to a predetermined torque, to thereby wind the webbing on the spool.

Abstract: A seat belt retractor includes a base frame, a spool journalled to the base frame, a webbing wound around the spool, and a motor for rotating the spool. A speed-reduction mechanism is interposed between the motor and the spool. The speed-reduction mechanism includes at least one transmission train with a predetermined gear ratio, a common transmission element connected to the transmission train, and a resistant torque device connected to the transmission train. The common transmission element transmits rotation of the motor to the spool when the torque of the rotation is smaller than the preset value. Winding of the webbing is made based on the wearing condition of the webbing and the running condition of the vehicle.

Abstract: A seat belt retractor includes a base frame, a spool journalled to the base frame, a webbing wound around the spool, and a motor for rotating the spool. A speed-reduction mechanism is interposed between the motor and the spool. The speed-reduction mechanism includes at least one transmission train with a predetermined gear ratio, a common transmission element connected to the transmission train, and a resistant torque device connected to the transmission train. The common transmission element transmits rotation of the motor to the spool when the torque of the rotation is smaller than the preset value. Winding of the webbing is made based on the wearing condition of the webbing and the running condition of the vehicle.

Abstract: A buckle is provided with a non-contact buckle switch to find an engagement condition with a tongue. When a lock member of the buckle is disposed in a locking position, a magnetic field produced by a magnet and applied to an IC Hall element differs from a case where the lock member is disposed in a non-locking position. The difference of the magnetic field is caused by the magnetic lock member moved close to the magnet and the IC Hall element, whereby an electrical current outputted by the electromotive force of the IC Hall element is changed. Thus, it is possible to determine that the lock pin is set in the locking position. The buckle switch is improved in durability and can operate more reliably.