Patents by Inventor Ko-ichi Kawahara

Ko-ichi Kawahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same
    Patent number: 10627412
    Abstract: The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.
    Type: Grant
    Filed: March 17, 2011
    Date of Patent: April 21, 2020
    Assignee: KAGOSHIMA UNIVERSITY
    Inventors: Ikuro Maruyama, Teruto Hashiguchi, Salunya Tancharoen, Ko-ichi Kawahara, Kenji Tanaka, Lyang-ja Lee
  • PERIODONTAL-DISEASE-SPECIFIC PEPTIDE, AND TREATMENT AND DIAGNOSIS OF PERIODONTAL DISEASE USING SAME
    Publication number: 20130086703
    Abstract: The present invention provides an inhibitor of an autoimmune response to a periodontal bacterial enzymatic degradation product of keratin in gingival epithelium in a mammal having a periodontal bacterium in the oral cavity, containing a substance having affinity to the keratin or a degradation product thereof and/or a substance having affinity to an autoantibody to the degradation product, an agent for the prophylaxis and/or treatment of a periodontal disease and/or a complication thereof; a RANKL expression inhibitor containing a substance having affinity to the keratin or a degradation product thereof; and a method of diagnosing a periodontal disease including detecting the keratin or a degradation product thereof and/or an autoantibody thereto.
    Type: Application
    Filed: March 17, 2011
    Publication date: April 4, 2013
    Inventors: Ikuro Maruyama, Teruto Hashiguchi, Salunya Tancharoen, Ko-ichi Kawahara, Kenji Tanaka, Lyang-Ja Lee