Abstract: An incubator includes: an insulated box including an incubation space surrounded by multiple inner faces; a humidifying unit that humidifies an incubation space; a first heating unit that heats a first inner face among the multiple inner faces, with electric power supplied; a second heating unit that heats a second inner face, different from the first inner face, with electric power supplied; and a control unit that controls the magnitude of electric power supplied to each of the first heating unit and the second heating unit. The control unit repeatedly changes the magnitude of electric power supplied to the first heating unit at first timing, and also repeatedly changes the magnitude of electric power supplied to the second heating unit at second timing different from the first timing.

Abstract: The invention pertains to biomarkers for identifying a cancer that is likely or not likely to evade the immune system of a subject, thus, is likely or not likely to show better prognosis (prognostic biomarker) and/or better responses to cancer therapies (predictive biomarker). The invention provides a method of identifying a subject as having a cancer that is likely to evade the immune system of the subject based on one or more of the following biomarkers in the cancer cells of the subject: a) reduced amount of NLRC5 mRNA or protein; b) reduced activity of NLRC5 protein; c) a mutation that reduces the activity of NLRC5 protein; d) increased methylation of nlrc5 or a portion thereof; and e) reduced copy number of nlrc5. These variables are useful to predict both patient survival (prognostic biomarker) and patient responses to immunotherapies (predictive biomarker).

Abstract: An isolator system including: a box-shaped body case having, in an interior thereof, a work space for operation in a sterile environment and also having, in a front surface thereof, an insertion portion into which a worker's arm is inserted; and an air-conditioning portion configured to supply gas in the work space of the body case or to discharge gas in the work space, a bottom of the work space being configured with a work plate, a discharge path configured to discharge gas in the work space being formed below the work plate, the work plate being configured with first and second work plates obtained by dividing the work plate into right and left parts, a receiving portion being located below the first work plate, the receiving portion being arranged extending towards the second work plate on a side edge of the first work plate, the side edge of the first work plate being in contact with the second work plate, a side edge of the second work plate for being in contact with the first work plate being placed de

Abstract: An isolator includes: a chamber including a working chamber in which a work is performed by a worker, and a storage chamber provided under the working chamber in communication with an opening formed in a bottom plate of the working chamber, the chamber being configured to isolate the working chamber and the storage chamber from an exterior while in a state where airtightness is maintained; and a lifting device configured to support, in the storage chamber, an experimental device to be used in the working chamber, the lifting device being capable of lifting and lowering the experimental device from the storage chamber to the working chamber and from the working chamber to the storage chamber.

Abstract: An ejection device includes a discharger that discharges liquid droplets on an object while moving in at least a first direction, a camera that images the object, and a camera protector that covers a light receiving surface of the camera when the discharger discharges the liquid droplets.

Abstract: An ejection device is provided, which is capable of restricting movement of an object so as to discharge droplets of a fluid to the object stably as well as suppressing generation of static electricity. The ejection device has a discharge part, discharging a droplet to an object; a base, electrically grounded; and a fixing mechanism, disposed on the base and fixing the object. The fixing mechanism includes an electrically conductive material and is electrically connected with the base.

Abstract: An isolator system includes first and second isolators respectively forming first and second workspaces hermetically sealed from ambient environment, and a pass box provided between the first and second isolators and forming a transport space enabled to communicate the first and second workspaces while maintaining hermeticity, wherein the pass box has a tray on which an article used in work is mounted, and a moving mechanism enabling movement of the tray toward directions to both sides of the first and second isolators, the tray has a first end on the first isolator side located in the first workspace when moved to the first isolator side, and a second end on the second isolator side located in the second workspace when moved to the second isolator side, and the first and second ends of the tray each has a grip bended downward from a mounting face of the tray.

Abstract: An isolator system including: a box-shaped body case having, in an interior thereof, a work space for operation in a sterile environment and also having, in a front surface thereof, an insertion portion into which a worker's arm is inserted; and an air-conditioning portion configured to supply gas in the work space of the body case or to discharge gas in the work space, a bottom of the work space being configured with a work plate, a discharge path configured to discharge gas in the work space being formed below the work plate, the work plate being configured with first and second work plates obtained by dividing the work plate into right and left parts, a receiving portion being located below the first work plate, the receiving portion being arranged extending towards the second work plate on a side edge of the first work plate, the side edge of the first work plate being in contact with the second work plate, a side edge of the second work plate for being in contact with the first work plate being placed de

Abstract: A working chamber including: a body case including a work space in an interior thereof; a supply unit configured to supply gas through a supply filter provided at the upper front of the work space; a louver that guides gas to a back surface side of the work space after the gas passes through the supply filter; and an illuminating means positioned lower than the louver and in front of the louver, at least one surface of the louver, which faces the illuminating means, being a reflection surface.

Abstract: A working chamber includes: a body case including a work space; a supply device configured to supply gas in a body case; a work plate having an opening formed therein, the work plate configuring a bottom surface of the work space; and an observation device capable of being lifted and lowered, and the observation device includes a receiving portion having a width greater than a gap between the work plate and the observation device in an in-use state, and the receiving portion is configured to close the gap between the observation device and the work plate in the in-use state.

Abstract: An isolator includes: a contamination-target chamber including an inlet and outlet having intake and discharge filters, respectively; and a decontaminating-gas-supply unit to supply decontaminating gas into the chamber without flowing through the filters, the unit including: an atomizer including first and second ports and a nozzle; a first pipe having one and the other ends connected to a compressor and the first port, respectively; a second pipe having one end connected to the second port and the other end open; a reservoir; a pump to take in decontamination solution from the reservoir; and a third pipe, having one end connected to the pump, thorough which the solution flows, the atomizer configured to, when injecting from the nozzle intake air from the first port, suction the solution, via the second pipe, by negative pressure produced in the second port; and inject the solution in an atomized state, mixing it with air.

Abstract: A sterilizing component removal device which reduces a sterilizing component sprayed in a working chamber having an outlet includes a sprayer which supplies, in an atomized manner, a liquid different from the sterilizing component into the working chamber.

Abstract: An isolator attached with gloves, includes: a main body case including a work space isolated from an exterior thereof; a work plate provided within the main body case, the work plate having formed therein an opening portion connecting a device provided below the main body case and the work space; a first cover member mounted to the work plate in a manner openable and closable with respect to the opening portion, the first cover member having formed therein a hole portion into which a worker's finger is to be inserted; and a second cover member mounted to the first cover member in a manner openable and closable with respect to the hole portion.

Abstract: An isolator including: a main body case including a box-shaped working space and provided with an inserting portion of a work hand on a front surface thereof; an illuminating device that illuminates the inside of the main body case; and an air-conditioning device that performs air conditioning inside the main body case, the illuminating device having a plurality of point light sources that are arranged substantially linearly in the main body case, the main body case including a back plate or a bottom plate, at least one of the back plate or the bottom plate being constituted by a metal plate, and a rolling direction of the back plate or the bottom plate constituted by the metal plate being a direction substantially orthogonal to an arrangement direction of the plurality of point light sources.

Abstract: An isolator system includes: a main body case including a substantially box-shaped work space isolated from its surroundings; a spray device configured to spray a sterilizing mist from a nozzle mounted within the main body case, the sterilizing mist being obtained by converting a sterilizing liquid into mist; a diffusion fan mounted within the main body case to diffuse the sterilizing mist; and a control device configured to control operations of the spray device and the diffusion fan, the spray device being configured to spray the sterilizing mist when spraying, the diffusion fan being configured to be intermittently operated in the spray process of the spray device, the diffusion fan being configured to be continuously operated from an end of the spray process of the spray device.

Abstract: An isolator system includes first and second isolators respectively forming first and second workspaces hermetically sealed from ambient environment, and a pass box provided between the first and second isolators and forming a transport space enabled to communicate the first and second workspaces while maintaining hermeticity, wherein the pass box has a tray on which an article used in work is mounted, and a moving mechanism enabling movement of the tray toward directions to both sides of the first and second isolators, the tray has a first end on the first isolator side located in the first workspace when moved to the first isolator side, and a second end on the second isolator side located in the second workspace when moved to the second isolator side, and the first and second ends of the tray each has a grip bended downward from a mounting face of the tray.

Abstract: A carrier for holding a wheel unit, which is easy and simple to handle (operate), and is capable of exactly switching a condition in which a rotation of a rear wheel is restricted, and a condition in which the rotation of the rear wheel is allowed is proposed. The carrier includes: a body; a sliding member capable of being slid in one direction and held on one of a first holding position and a second holding position; an urging member urging the sliding member along the one direction. The position on which the sliding member is held after the sliding member has been returned by an urging force of the urging member, is alternately changed between the first holding position and the second holding position.

Abstract: A medicine supply apparatus which comprises, in a case accommodating section 8, a plurality of tablet cases 3 for accommodating medicine and charges or supplies medicine into a bag 72, which medicine has been discharged from each tablet case 3 based on a prescription. An identification code 26 is provided for each of the tablet cases 3 and read by an optical sensor 33 provided inside the case accommodating section 8, whereby discharge of medicine is controlled. A motor 14 for driving a discharge drum for the tablet case 3 is checked for disconnection by being regularly energized. The operating time and the frequency of operation of parts that wear out, such as the motors, are stored for use in failure prediction. Time slots in which medicine should be taken are printed, each in a different color, by a color printing mechanism 73 on the bag 72 into which medicine is charged.

Abstract: An isolator includes: a working chamber in which work is conducted; an atomizer configured to atomize air or a decontamination material in the working chamber: a pump configured to supply the decontamination material to the atomizer; a compressor configured to supply air to the atomizer; a pressure sensor configured to measure an internal pressure of the working chamber; and a control unit configured to perform a leak test, in which the compressor is driven to supply air from the atomizer into the working chamber thereby pressuring the working chamber, and airtightness of the working chamber is tested based on the internal pressure of the working chamber measured by the pressure sensor.

Abstract: An isolator includes: a chamber including a working chamber in which a work is performed by a worker, and a storage chamber provided under the working chamber in communication with an opening formed in a bottom plate of the working chamber, the chamber being configured to isolate the working chamber and the storage chamber from an exterior while in a state where airtightness is maintained; and a lifting device configured to support, in the storage chamber, an experimental device to be used in the working chamber, the lifting device being capable of lifting and lowering the experimental device from the storage chamber to the working chamber and from the working chamber to the storage chamber.