Patents by Inventor Koichi Kotaka
Koichi Kotaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11692015Abstract: The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)nmotif-REP]m or Formula 2: [(A)nmotif-REP]m?(A)n motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin.Type: GrantFiled: July 25, 2018Date of Patent: July 4, 2023Assignees: Spiber Inc., RikenInventors: Keisuke Morita, Yunosuke Abe, Takehisa Maekawa, Koichi Kotaka, Junichi Sugahara, Keiji Numata
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Publication number: 20220127755Abstract: An object of the present invention is to provide a method for producing an artificial structural protein fiber having a small diameter and having a stress equal to or higher than that of the related art. A method for producing an artificial structural protein fiber according to the present invention is a method for producing an artificial structural protein fiber by a wet spinning method, the method including a coagulation step of discharging a spinning dope containing an artificial structural protein and an organic solvent from a spinneret into a coagulation liquid to coagulate the artificial structural protein, wherein a bath draft in the coagulation step is more than 0.4 and 20 or less.Type: ApplicationFiled: February 7, 2020Publication date: April 28, 2022Applicant: Spiber Inc.Inventors: Hirotada Ando, Hideto Ishii, Koichi Kotaka, Ryoko Sato, Hiroshi Kano, Jun Kobayashi, Akito Sato, Yunosuke Abe
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Publication number: 20220010460Abstract: An object of the present invention is to provide a method for producing a modified fibroin multifilament excellent in productivity and a multifilament produced by the same. The multifilament of the present invention contains modified fibroin, in which the multifilament has 100 or more constituent single yarns, a coefficient of variation in elastic modulus is 15% or less, a coefficient of variation in strength is 15% or less, and a coefficient of variation in elongation is less than 33%.Type: ApplicationFiled: February 7, 2020Publication date: January 13, 2022Inventors: Yunosuke ABE, Hideto ISHII, Ryoko SATO, Akito SATO, Hirotada ANDO, Hiroshi KANO, Koichi KOTAKA, Jun KOBAYASHI
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Publication number: 20210395317Abstract: Disclosed is a method for producing a protein fiber, the method including: bringing a spinning dope containing a protein and an organic solvent into contact with a coagulation liquid to coagulate the protein, wherein a content of the protein in the spinning dope is more than 10% by mass based on a total amount of the spinning dope, and the coagulation liquid contains water or an aqueous solution of pH 0.25 or more and pH 10.00 or less.Type: ApplicationFiled: September 30, 2019Publication date: December 23, 2021Applicant: Spiber Inc.Inventors: Yunosuke Abe, Hirotada Ando, Koichi Kotaka
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Publication number: 20200207817Abstract: The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)n motif-REP]m or Formula 2: [(A)n motif-REP]m-(A)n motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin. [In Formula 1 and Formula 2, (A)n motif represents an amino acid sequence consisting of 4 to 27 amino acid residues, and the number of alanine residues with respect to the total number of amino acid residues in the (A)n motif is 80% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300. A plurality of (A)n motifs may be the same amino acid sequence or different amino acid sequences.Type: ApplicationFiled: July 25, 2018Publication date: July 2, 2020Applicants: Spiber Inc., RikenInventors: Keisuke Morita, Yunosuke Abe, Takehisa Maekawa, Koichi Kotaka, Junichi Sugahara, Keiji Numata
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Publication number: 20190352330Abstract: The present invention relates to a method for recovering protein, which recovers a target protein from a mixture containing the target protein and a material different from the target protein, the method including a dissolution step of dissolving either the target protein or the material by applying pressure while heating to a solution for dissolution containing the mixture and a polar solvent, and a separation step of separating an obtained solution.Type: ApplicationFiled: December 25, 2017Publication date: November 21, 2019Applicant: Spiber Inc.Inventors: Kazuhide Sekiyama, Akihiko Ozeki, Ryoji Okada, Koichi Kotaka
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Publication number: 20190233481Abstract: The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)n motif-REP]m, in which the domain sequence has an amino acid sequence locally containing a region with locally high hydropathy index equivalent to an amino acid sequence in which one or a plurality of amino acid residues in REP are substituted with amino acid residues with a high hydropathy index and/or one or a plurality of amino acid residues with a high hydropathy index are inserted into REP, as compared to naturally occurring fibroin. In Formula 1, (A)n motif represents an amino acid sequence consisting of 4 to 20 amino acid residues and the number of alanine residues relative to the total number of amino acid residues in the (A)n motif is 83% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300, A plurality of (A)n motifs and the like may be the same amino acid sequence or different amino acid sequences.Type: ApplicationFiled: June 23, 2017Publication date: August 1, 2019Applicants: Spiber Inc., KOJIMA INDUSTRIES CORPORATIONInventors: Keisuke MORITA, Koichi KOTAKA
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Publication number: 20190194403Abstract: The present invention provides a method for producing a molded article including a step 1 of adding water to a composition including a structural protein, a step 2 of molding a water-containing composition obtained in the step 1, and a step 3 of drying the molded composition obtained in the step 2 to obtain the molded article.Type: ApplicationFiled: September 1, 2017Publication date: June 27, 2019Applicants: Spiber Inc., Tekunohama Co., Ltd.Inventors: Shinji Hirai, Yukimasa Ubukata, Ayumi Abe, Koichi Kotaka, Yuki Nakayama, Junichi Noba
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Publication number: 20180355120Abstract: Provided is a method for producing a protein solution, including applying a pressure to a dispersion liquid containing a protein and a polar solvent in which the protein is dispersed, to obtain a protein solution containing the protein and the polar solvent in which the protein is dissolved.Type: ApplicationFiled: November 29, 2016Publication date: December 13, 2018Applicants: Spiber Inc., Kojima Industries Corporation, Tekunohama Co., Ltd.Inventors: Koichi Kotaka, Takaoki Ishii, Junichi Sugahara, Ryota Sato, Junichi Noba