Patents by Inventor Koichi Nonaka
Koichi Nonaka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12275665Abstract: A glass composition for glass fibers including 50.0 to 70.0% by mass of SiO2, 10.0 to 30.0% by mass of Al2O3, 8.0 to 25.0% by mass of ZnO, 0.0 to 8.0% by mass of MgO, 0.0 to 5.0% by mass of CaO, 0.0 to 8.0% by mass of P2O5, 0.0 to 2.5% by mass of TiO2, and 0.0% by mass or more and less than 1.0% by mass in total of Li2O, Na2O, and K2O, and when the contents of SiO2, Al2O3, ZnO, MgO, CaO, and P2O5 are defined as S, A, Z, M, C, and P, respectively, (M+C)/Z is 0.46 or less and the S, A, and P satisfy the following formula (1-1): 28.0?{(S?P)×(A?P)}1/2?36.9 . . . (1-1).Type: GrantFiled: April 5, 2023Date of Patent: April 15, 2025Assignee: Nitto Boseki Co., Ltd.Inventors: Ryo Nishikubo, Tatsuya Komukai, Tadashi Kurita, Koichi Nakamura, Takashi Nonaka
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Publication number: 20230257767Abstract: The present invention provides an approach to enhancing the production of a foreign protein serving as a protein-based pharmaceutical product in host cells such as cultured cells derived from a mammal. The present invention provides transformed cells having a novel Hspa5 gene promoter, and a method for secreting and producing a foreign protein at high levels using the transformed host cells.Type: ApplicationFiled: January 12, 2023Publication date: August 17, 2023Applicant: Daiichi Sankyo Company, LimitedInventors: Kenji Masuda, Koichi Nonaka, Hiroki Tanemura
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Patent number: 11555204Abstract: The present invention provides an approach to enhancing the production of a foreign protein serving as a protein-based pharmaceutical product in host cells such as cultured cells derived from a mammal. The present invention provides transformed cells having a novel Hspa5 gene promoter, and a method for secreting and producing a foreign protein at high levels using the transformed host cells.Type: GrantFiled: October 2, 2017Date of Patent: January 17, 2023Assignee: Daiichi Sankyo Company, LimitedInventors: Kenji Masuda, Koichi Nonaka, Hiroki Tanemura
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Publication number: 20210317498Abstract: The present invention provides an approach to enhancing the production of a foreign protein serving as a protein-based pharmaceutical product in host cells such as cultured cells derived from a mammal. The present invention provides transfected cells having a novel Hspa8 gene promoter, and a method for secreting and producing a foreign protein at high levels using the transfected cells.Type: ApplicationFiled: August 8, 2019Publication date: October 14, 2021Applicant: Daiichi Sankyo Company, LimitedInventors: Kenji Masuda, Yuto Nakazawa, Kazuhiko Watanabe, Maui Nishio, Takeshi Okumura, Koichi Nonaka
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Publication number: 20190241907Abstract: The present invention provides an approach to enhancing the production of a foreign protein serving as a protein-based pharmaceutical product in host cells such as cultured cells derived from a mammal. The present invention provides transformed cells having a novel Hspa5 gene promoter, and a method for secreting and producing a foreign protein at high levels using the transformed host cells.Type: ApplicationFiled: October 2, 2017Publication date: August 8, 2019Applicant: Daiichi Sankyo Company, LimitedInventors: Kenji Masuda, Koichi Nonaka, Hiroki Tanemura
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Publication number: 20170211063Abstract: The object of the present invention is to provide a production system that is capable of high-level secretory production of a protein (and in particular, a protein with a complicated structure such as a structure with S—S bonds) in a host cell such as yeast and is suitable for industrial production with high safety that does not require explosion-proof facilities. The present invention provides a transformed yeast into which a chaperone gene has been introduced and in which the aox1 gene and/or the protease gene have been disrupted and a method for producing a protein involving the use of such transformed yeast.Type: ApplicationFiled: July 29, 2015Publication date: July 27, 2017Applicant: Daiichi Sankyo Company, LimitedInventors: Koichi NONAKA, Takeshi SUZUKI, Masashi TSUDA, Satoshi BABA, Kimihisa ICHIKAWA, Yasunori CHIBA, Takehiko YOKO-O, Rie ITO
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Patent number: 8409825Abstract: This invention provides a means for high-level secretory production of a protein, and, in particular, a protein having a complicated structure such as an antibody, in a host cell such as a yeast cell. This invention provides a method for high-level secretory production of a foreign protein with the use of a transformed host cell having one or more types of chaperone protein genes and via suppression of O sugar chain inherent to a host cell such as a yeast cell.Type: GrantFiled: October 29, 2008Date of Patent: April 2, 2013Assignees: National Institute of Advanced Industrial Science and Technology, Kyowa Hakko Kirin Co., Ltd, Daiichi Sankyo Company, LimitedInventors: Yasunori Chiba, Yoshifumi Jigami, Yoshie Takahashi, Kosuke Kuroda, Kazuo Kobayashi, Kimihisa Ichikawa, Koichi Nonaka, Takeshi Suzuki, Minako Ono
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Patent number: 8232377Abstract: This invention provides a means for enabling high-level secretory production of proteins, in particular proteins having complicated structures such as antibodies, in host cells such as yeast cells. The invention also provides transformed yeast cells having the activated HAC1 gene and the RRBP1 gene and a method for enabling high-level secretory production of foreign proteins using such transformed host cells by inhibiting O-sugar chain formation indigenous to host cells such as yeast cells.Type: GrantFiled: May 16, 2007Date of Patent: July 31, 2012Assignees: National Institute of Advanced Industrial Science and Technology, Kyowa Hakko Kirin Co., Ltd., Daiichi Sankyo Company, LimitedInventors: Yasunori Chiba, Yoshifumi Jigami, Kosuke Kuroda, Kazuo Kobayashi, Kimihisa Ichikawa, Koichi Nonaka, Takeshi Suzuki
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Publication number: 20120036310Abstract: A data processing device is provided enabling faster read access to data in an on-chip EEPROM with relative ease, without increasing the area occupied by the chip and its power consumption. The on-chip nonvolatile memory included in the data processing device is provided with a pre-read cache which latches all or part of data, once having been read to bit lines from an array of nonvolatile memory cells by selecting a row address, and a selecting circuit which selects a portion of the data latched by the pre-read cache by selecting a portion of columns. Control is performed to retain address information for data latched by the pre-read cache, inhibit latching new data into the pre-read cache for read access to data in the nonvolatile memory according to the same address as the retained address information, and cause the selecting circuit to select the data latched by the pre-read cache.Type: ApplicationFiled: August 3, 2011Publication date: February 9, 2012Inventors: Koichi NONAKA, Satoru Nakanishi
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Publication number: 20110014651Abstract: This invention provides a means for high-level secretory production of a protein, and, in particular, a protein having a complicated structure such as an antibody, in a host cell such as a yeast cell. This invention provides a method for high-level secretory production of a foreign protein with the use of a transformed host cell having one or more types of chaperone protein genes and via suppression of O sugar chain inherent to a host cell such as a yeast cell.Type: ApplicationFiled: October 29, 2008Publication date: January 20, 2011Applicants: KYOWA HAKKO KIRIN CO., LTD., DAIICHI SANKYO COMPANY, LIMITEDInventors: Yasunori Chiba, Yoshifumi Jigami, Yoshie Takahashi, Kosuke Kuroda, Kazuo Kobayashi, Kimihisa Ichikawa, Koichi Nonaka, Takeshi Suzuki, Minako Ono
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Publication number: 20090191587Abstract: This invention provides a means for enabling high-level secretory production of proteins, in particular proteins having complicated structures such as antibodies, in host cells such as yeast cells. The invention also provides transformed yeast cells having the activated HAC1 gene and the RRBP1 gene and a method for enabling high-level secretory production of foreign proteins using such transformed host cells by inhibiting O-sugar chain formation indigenous to host cells such as yeast cells.Type: ApplicationFiled: May 16, 2007Publication date: July 30, 2009Inventors: Yasunori Chiba, Yoshifumi Jigami, Kosuke Kuroda, Kazuo Kobayashi, Kimihisa Ichikawa, Koichi Nonaka, Takeshi Suzuki