Patents by Inventor Koichi Okabe

Koichi Okabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11965180
    Abstract: Provided is a cancer stem cell mass from which cells incapable of forming cancer are substantially removed and which has a characteristic property of reproducing a layered structure of a cancer tissue; a process for producing the cancer stem cell mass; and use of the cancer stem cell mass. A human cancer tissue was repeatedly grown in a NOG mouse, separated cancer cells from the grown cancer tissue, and tested and compared various cancer cell culture processes. As a result, a cancer stem cell composition which is homogeneous and is substantially free of the coexistence of cells capable of forming cancer and cells incapable of forming cancer in a mixed state can be produced successively by employing an attached culture process using a serum-free stem cell culture medium rather than a generally employed floating culture process.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: April 23, 2024
    Assignee: Chugai Seiyaku Kabushiki Kaisha
    Inventors: Tatsumi Yamazaki, Hisafumi Okabe, Shinta Kobayashi, Yu Jau Chen, Atsuhiko Kato, Masami Suzuki, Koichi Matsubara
  • Patent number: 11927451
    Abstract: Provided is a route search device and a non-transitory computer-readable medium that can search a route where a transportation means more suitable for a user is selected. When searching a route to a destination, a change point at which the transportation means is changed is set, and then the priority in selecting a transportation means for moving in a section from a plurality kinds of transportation means is set based on at least one of an attribute of a start point and an attribute of an end point in the section for each section where a distance between a departure place and a destination is divided at the change point to search the route to the destination using the transportation means selected for each of the plurality of sections based on the set priority.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: March 12, 2024
    Assignee: TOYOTA JIDOSHA KABUSHIKI KAISHA
    Inventors: Motohiro Nakamura, Yoko Sakurai, Norihiro Nakamura, Hidefumi Okabe, Naoto Miura, Koichi Iwatsuki
  • Publication number: 20090318453
    Abstract: The invention provides a method for treatment of gastric cancer, which method is a postoperative adjuvant chemotherapy for gastric cancer, comprising orally administering, to a patient with gastric cancer in stage II, IIIA, or IIIB in a classification of the stage of gastric cancer, a pharmaceutical composition containing Tegafur, Gimeracil, and Oteracil potassium at a molar ratio of 1:0.4:1, at a dose of 50 to 150 mg/day as Tegafur dose and according to an administration schedule including, from within 45 days after a surgical operation of gastric cancer, drug administration for 28 consecutive days, followed by a rest period of 7 to 14 consecutive days. The chemotherapy reduces the relapse rate after a surgical operation, thereby improving the survival rate.
    Type: Application
    Filed: September 20, 2007
    Publication date: December 24, 2009
    Applicant: TAIHO PHARMACEUTICAL CO., LTD
    Inventor: Koichi Okabe
  • Patent number: 5232215
    Abstract: A sheet feed cassette to be installed to a sheet feed unit of an image forming apparatus. The sheet feed cassette includes a frame unit having at least a side frame and a bottom frame; a bottom plate, provided above the bottom frame of the frame unit, for placing and supporting sheets thereon, the bottom plate being capable of moving up and down; a pushing-up unit, provided at a front end portion of a sheet feed side of the bottom plate, for pushing up the bottom plate with respect to the bottom frame of the frame unit when the sheet feed cassette is installed to the sheet feed unit of the image forming apparatus; and a spring, provided at an end portion opposite to the sheet feed side of the bottom plate, for urging up the bottom plate with respect to the bottom frame of the frame unit.
    Type: Grant
    Filed: April 27, 1992
    Date of Patent: August 3, 1993
    Assignee: Fuji Xerox Co., Ltd.
    Inventors: Yusaku Hashimoto, Hidekazu Amamoto, Naomasa Okimura, Koichi Okabe
  • Patent number: 5210730
    Abstract: In a multi-beam optical disk device in which a signal is recorded on or reproduced from an optical disk by means of a plurality of light beams, a tracking error detecting apparatus is constructed such that the plurality of light beams projected from an optical head are made incident upon the optical disk and one of these light beams is made incident upon a groove formed in the optical disk and a first tracking error signal is derived from the one light beam reflected by or transmitted through the groove, and all the light beams are made incident upon a groove formed in the optical disk and a second tracking error signal is derived from all the beams reflected by or transmitted through the groove.
    Type: Grant
    Filed: January 17, 1991
    Date of Patent: May 11, 1993
    Assignee: Asaca Corporation
    Inventors: Akio Hayashi, Koichi Okabe, Shozo Nakagawa