Patents by Inventor Koichi Takakura
Koichi Takakura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11948754Abstract: A three-terminal capacitor includes a main body having a cylindrical or substantially cylindrical shape extending in a first direction and including first and second inner electrodes alternately laminated together with dielectric layers interposed therebetween, a pair of first outer electrodes on two end surfaces of the main body in the first direction and electrically connected to the first inner electrodes, and a second outer electrode electrically connected to the second inner electrodes. The main body includes a projecting portion projecting in a direction perpendicular or substantially perpendicular to the first direction at a position between the pair of first outer electrodes. The second outer electrode is provided on one surface of the projecting portion viewable when viewed in the first direction.Type: GrantFiled: October 14, 2021Date of Patent: April 2, 2024Assignee: MURATA MANUFACTURING CO., LTD.Inventors: Shingo Ito, Koichi Ikeda, Ken Takakura, Satoshi Yoshida, Syuichi Nabekura, Takahiro Hirao, Masanori Nakamura, Kyosuke Uno, Haruhiko Ueno, Yohei Mukobata
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Patent number: 5192684Abstract: A human IgG.sub.1 type monoclonal antibody which possesses a molecular weight in the range of 180,000.+-.20,000 as measured by the method of polyacrylamide gel electrophoresis performed in the presence of sodium dodecyl sulfate and is specific to nicotinic acetylcholine receptor. The human IgG.sub.1 type monoclonal antibody mentioned above is produced by a method which comprises fusing human cells capable of producing an antibody against nicotinic acetylcholine receptor with propagable human cells thereby giving rise to a hybridoma capable of producing the aforementioned human IgG.sub.1 type monoclonal antibody, selecting the hybridoma from the production of the fusion, culturing the hybridoma thereby giving rise to the aforementioned human IgG.sub.1 type monoclonal antibody, and selecting the antibody from the cultured medium. The hybridoma mentioned above is also identified.Type: GrantFiled: March 30, 1988Date of Patent: March 9, 1993Assignees: Agency of Industrial Science & Technology, Ministry of International Trade and IndustryInventors: Masao Tanihara, Hideaki Yamada, Toshihide Nakashima, Yoshiaki Omura, Koichi Takakura
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Patent number: 5132402Abstract: There is disclosed an adsorbent, comprising a carrier on which is immobilized a peptide possessing an ability to bind to the human antibody to the nicotinic acetylcholine receptor and represented by the formula:H--X--A--Y--Zwherein A stands for a peptide residue, one of X and Y stands for a single bond, an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR1## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and the other of X and Y stands for an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR2## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and Z standType: GrantFiled: November 1, 1988Date of Patent: July 21, 1992Assignees: Agency of Industrial Science and Technology, Ministry of International Trade and IndustryInventors: Masao Tanihara, Kiichiro Oka, Hideaki Yamada, Akira Kobayashi, Toshihide Nakashima, Yoshiaki Omura, Koichi Takakura
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Patent number: 5019486Abstract: A method for forming plate characters in a half-tone gravure platemaking process in which a laser beam intermittently irradiates a photosensitive material, thus forming plate characters therein as a result of exposure by the laser beam. The outline portion of each character is made up of continuous groove-form cells and inner portion of the character (the filled portion) is made up of independent dot-form cells corresponding to the dot percentage of a shadow portion or with island-form projections to the extent that ink flow (running) does not occur when the cells are filled with ink as a result of the plate surface being wiped by a doctor blade. The outline portion of each character is made up of groove-form cells having a narrow width without causing ink flow (running) when the cells are filled with ink as a result of the plate surface being wiped by a doctor blade.Type: GrantFiled: February 8, 1990Date of Patent: May 28, 1991Assignee: Think Laboratory Co., Ltd.Inventor: Koichi Takakura
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Patent number: 4925787Abstract: A monoclonal anti-idiotypic antibody specific to a human IgG.sub.1 type monoclonal antibody possessing specificity to nicotinic acetylcholine receptor; a method for the production of the aforementioned monoclonal anti-idiotypic antibody by the steps of immunizing an animal with a human IgG.sub.1 type monoclonal antibody specific to nicotinic acetylcholine receptor, collecting antibody-producing cells from the animal, fusing the collected cells with neoplastic cells, selecting from the product of fusion a hybridoma capable of producing a monoclonal anti-idiotypic antibody specific to the human IgG.sub.1 type monoclonal antibody possessing specificity to nicotinic acetylcholine receptor, propagating the selected hybridoma thereby giving rise to said monoclonal anti-idiotypic antibody, and collecting the produced monoclonal anti-idiotypic antibody; and use of the monoclonal anti-idiotypic antibody as a reagent and as an adsorbent.Type: GrantFiled: March 30, 1988Date of Patent: May 15, 1990Assignees: Agency of Industrial Science and Technology, Ministry of International Trade and IndustryInventors: Masao Tanihara, Hideaki Yamada, Toshihide Nakashima, Yoshiaki Omura, Koichi Takakura
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Patent number: 4889917Abstract: A peptide is disclosed which is represented by the formula:H-X-Gly-Trp-Lys-His-Trp-Val-Tyr-Tyr-Thr-Cys-Cys-Pro-Asp-Thr-Pro-Tyr-Leu-Asp -Y -Zwherein one of X and Y stands for a single bond, an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR1## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above, the other of X and Y stands for an amino acid residue selected from the class consisting of Asp, Glu, Lys and a divalent group represented by the formula, ##STR2## (wherein n stands for an integer in the range of 1 to 17), or a peptide residue formed by peptide linkage of two to ten amino acid residues of at least one species selected from the class mentioned above and Z stands for a hydroxyl group or an amino group, and two cysteinyl mercapto groups in the Cys-Cys moiety may be interlinked toType: GrantFiled: November 1, 1988Date of Patent: December 26, 1989Assignee: Agency of Industrial Science Technology, Ministry of International Trade & IndustryInventors: Masao Tanihara, Kiichiro Oka, Hideaki Yamada, Akira Kobayashi, Toshihide Nakashima, Yoshiaki Omura, Koichi Takakura
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Patent number: 4472303Abstract: Treatment of the blood by means of a blood purification device comprising packed, substantially spherical, smooth-surfaced, porous granules having at least 0.1 .mu.mole/m.sup.2 of the silanol group on the surface thereof, a blood inlet and a blood outlet scarcely causes decrease in leukocyte or platelet count or blood cell damage and can remove proteins from the blood by adsorption without high pressure loss.Type: GrantFiled: August 22, 1983Date of Patent: September 18, 1984Assignee: Kuraray Co., Ltd.Inventors: Masao Tanihara, Toshihide Nakashima, Koichi Takakura
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Patent number: 4421684Abstract: A column for adsorption of blood proteins is disclosed which comprises a blood inlet and a blood outlet each with a filter, and a porous material packed between both the filters, which material has a mean pore diameter (D) of 30-3,000 amgstroms with the volume occupied by pores with diameters of 0.8D-1.2D being at least 80% of the whole pore volume. The adsorption column can eliminate specific blood proteins by selective adsorption and is useful in the treatment of autoimmune diseases and cancer, for instance.Type: GrantFiled: May 28, 1982Date of Patent: December 20, 1983Assignee: Kuraray Co., Ltd.Inventors: Toshihide Nakashima, Maso Tanihara, Koichi Takakura
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Patent number: 4420395Abstract: Treatment of the blood by means of a blood purification device comprising packed, substantially spherical, smooth-surfaced, porous granules having at least 0.1 .mu.mole/m.sup.2 of the silanol group on the surface thereof, a blood inlet and a blood outlet scarcely causes decrease in leukocyte or platelet count or blood cell damage and can remove proteins from the blood by adsorption without high pressure loss.Type: GrantFiled: July 7, 1982Date of Patent: December 13, 1983Assignee: Kuraray Co., Ltd.Inventors: Masao Tanihara, Toshihide Nakashima, Koichi Takakura
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Patent number: 4384954Abstract: A column for adsorption of blood proteins is disclosed which comprises a blood inlet and a blood outlet each with a filter, and a porous material packed between both the filters, which material has a mean pore diameter (D) of 30-3,000 angstroms with the volume occupied by pores with diameters of 0.8 D-1.2 D being at least 80% of the whole pore volume. The adsorption column can eliminate specific blood proteins by selective adsorption and is useful in the treatment of autoimmune diseases and cancer, for instance.Type: GrantFiled: April 3, 1981Date of Patent: May 24, 1983Assignee: Kuraray Co., Ltd.Inventors: Toshihide Nakashima, Maso Tanihara, Koichi Takakura
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Patent number: 4352884Abstract: Carriers coated with a copolymer of a hydrophilic acrylate or methacrylate monomer and a copolymerizable unsaturated carboxylic acid or unsaturated amine are provided which are substantially free from nonspecific adsorption of proteins and the like. Due to the side-chain carboxyl or amino groups of the copolymer, these coated carriers are able to immobilize bio-active materials such as antigens, antibodies, complements and enzymes. These carriers, on which bio-active materials can be immobilized, are useful as clinical selective adsorbents, affinity-chromatographic adsorbents, selective electrodes or columns for analysis.Type: GrantFiled: February 9, 1981Date of Patent: October 5, 1982Assignee: Kuraray Co., LtdInventors: Toshihide Nakashima, Masao Tanihara, Koichi Takakura
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Patent number: 4287177Abstract: The present invention provides a covering material consisting essentially of a hydrophilic, water insoluble polymer (component A), a high boiling plasticizer and/or organic solvent (component B) for said component A, and an aqueous liquid (component C). Said covering material is useful as a protective covering material for forming a film or coat on the skin and/or wound surface in the treatment of burn. The material is characterized in that film or coat formation on the skin and/or wound surface can be realized in a short time.Type: GrantFiled: August 15, 1979Date of Patent: September 1, 1981Assignees: Kuraray Co., Ltd., Yamanouchi Pharmaceutical Co., Ltd.Inventors: Toshihide Nakashima, Osamu Nakaji, Koichi Takakura, Takayoshi Suzuki
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Patent number: 4269713Abstract: There is described an ethylene-vinyl alcohol copolymer membrane comprising at least a skin layer on its surface and a porous layer supporting the skin layer. The porous layer, when the membrane is observed in the dry state with an electron microscope, contains vacuoles or voids, which present a mono- or multi-layer structure and have straight-line lengths corresponding to 20-99% of the whole thickness of the membrane. In addition, the polymer portion of the porous layer has micropores with an average pore diameter of 0.1-5 microns and the membrane has a porosity of 60-90%.Type: GrantFiled: August 31, 1979Date of Patent: May 26, 1981Assignee: Kuraray Co., Ltd.Inventors: Shuzo Yamashita, Syuji Kawai, Hirokuni Tanii, Koichi Takakura
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Patent number: 4171283Abstract: A hemoperfusion adsorbent is provided comprising an adsorbent material containing at least one coating thereon of a hydrophilic polymer prepared by the polymerization of at least one monomeric acrylate or methacrylate with a copolymerizable monomer containing an epoxy moiety therein.In addition, a method is provided for removing air bubbles from such adsorbents comprising boiling said adsorbents in water or physiological saline, cooling said adsorbents, packing said adsorbents into a container and sterilizing the packed container by autoclaving.Type: GrantFiled: July 29, 1977Date of Patent: October 16, 1979Assignee: Kuraray Co., Ltd.Inventors: Toshihide Nakashima, Koichi Takakura
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Patent number: 4134837Abstract: Ethylene-vinyl alcohol copolymer membranes characterized by constituent particles having an average diameter within the range of from 100 to 10,000 Angstrom units, determined under an electron microscope for the dry membrane, bonded to each other, wherein the membrane is substantially free from pores in excess of from 2 microns in diameter.Such a membrane has a permeability to water of 10 to 200 .times. 10.sup.-16 cm.sup.2 and to vitamin B.sub.12 of not less than 0.8 .times. 10.sup.-7 cm.sup.2 per second, and being of particular value as a membrane for the dialysis of blood.The membrane is obtained by dissolving an ethylenevinyl alcohol copolymer in a solvent consisting essentially of dimethylsulfoxide or dimethylacetamide and causing the resulting solution to coagulate from an aqueous coagulation bath under mild conditions such that the coagulation time as defined in the specification is not less than 3 seconds.Type: GrantFiled: June 10, 1976Date of Patent: January 16, 1979Assignee: Kuraray Co., Ltd.Inventors: Shuzo Yamashita, Shiro Nagata, Koichi Takakura
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Patent number: 4073733Abstract: A polyvinyl alcohol semi-permeable membrane is prepared which has micropores with an average diameter of 0.02 to 2 microns as defined by the interpore partition walls having thicknesses in the range of 50 to 5000 A and which is characterized by substantial cross-sectional uniformity. The membrane is prepared by extruding a PVA composition containing PAG with a molecular weight of 400 to 4,000 and a carbon-to-oxygen ratio of not more than 3 in a proportion of 2 to 200 parts by weight per 100 parts of PVA into a coagulation bath. In another embodiment of the invention, the membrane is formed from a PVA composition wherein the PAG has a molecular weight of 600 to 3,000 and a C/O ratio of not more than 3, the proportion of the PAG being 15 to 150 parts by weight per 100 parts of PVA and wherein the composition satisfies the relation: 0.65 .ltoreq. CBR (critical blending ratio) .ltoreq. 1.0. The membrane is useful in ultrafiltration, dialytic and osmotic separation applications.Type: GrantFiled: April 22, 1976Date of Patent: February 14, 1978Assignee: Kuraray Co., Ltd.Inventors: Kazuhisa Yamauchi, Koichi Takakura, Syuji Kawai, Akio Ohmori