Patents by Inventor Koichi Takayanagi

Koichi Takayanagi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fused imidazole derivative
    Patent number: 9096531
    Abstract: Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed: wherein n represents the number of nitrogen atoms contained in the 6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, —SO2— or —N(R9)—; and R1 to R5 each represents a hydrogen atom or other substituents.
    Type: Grant
    Filed: May 24, 2011
    Date of Patent: August 4, 2015
    Assignee: TOA EIYO LTD.
    Inventors: Hidekazu Masaki, Hiroshi Takasugi, Tomoyuki Nagayama, Ryutaro Shimono, Yujiro Uchino, Koichi Takayanagi
  • FUSED IMIDAZOLE DERIVATIVE
    Publication number: 20130065896
    Abstract: Provided is a novel compound which shows an antagonistic effect against T-type calcium channels, and is useful as a pharmaceutical product. A compound represented by general formula (I), and a pharmaceutical agent containing the same, are disclosed: wherein n represents the number of nitrogen atoms contained in the 6-membered fused aromatic ring, and is 0, 1 or 2; p represents the number of nitrogen atoms contained in the 6-membered aromatic ring, and is 0 or 1; X represents an oxygen atom, —SO2— or —N(R9)—; and R1 to R5 each represents a hydrogen atom or other substituents.
    Type: Application
    Filed: May 24, 2011
    Publication date: March 14, 2013
    Applicant: TOA Eiyo Ltd.
    Inventors: Hidekazu Masaki, Hiroshi Takasugi, Tomoyuki Nagayama, Ryutaro Shimono, Yujiro Uchino, Koichi Takayanagi
  • Cyclohepta[b]pyridine-3-carbonylguanidine derivative and pharmaceutical product containing same
    Patent number: 7875625
    Abstract: The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na+/H+ exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1): wherein R1 is a group selected from a sulfo group, a sulfoxy group, —OCONH—(CH2CH2O)n—SO3H and the following formulas: R2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: February 16, 2006
    Date of Patent: January 25, 2011
    Assignee: Toa Eiyo Ltd.
    Inventors: Kazuhiro Uemoto, Koichi Takayanagi, Shin-ichi Kazayama
  • Cyclohepta[B]Pyridine-3-Carbonylguanidine Derivative and Pharmaceutical Product Containing Same
    Publication number: 20090012114
    Abstract: The present invention relates to a medicine, particularly a medicine comprising a novel cyclohepta[b]pyridine-3-carbonylguanidine derivative having an inhibitory effect on an Na+/H+ exchanger (NHE). There is provided a cyclohepta[b]pyridine-3-carbonylguanidine derivative represented by Formula (1): wherein R1 is a group selected from a sulfo group, a sulfoxy group, —OCONH—(CH2CH2O)n—SO3H and the following formulas: R2 represents a halogen atom, a lower alkyl group or a lower alkoxy group; and n represents an integer from 1 to 10, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 16, 2006
    Publication date: January 8, 2009
    Applicant: TOA Eiyo Ltd.
    Inventors: Kazuhiro Uemoto, Koichi Takayanagi, Shin-ichi Kazayama
  • Halogenobenzyl aminopropionic acid derivatives
    Patent number: 6933309
    Abstract: A halogenobenzylaminopropionic acid derivative represented by the following formula (1): or a pharmaceutically acceptable salt of the derivative, and a drug containing the same as an active ingredient for treating diabetes, hyperlipidemia, or similar pathological conditions.
    Type: Grant
    Filed: December 26, 2002
    Date of Patent: August 23, 2005
    Assignee: Toaeiyo Ltd.
    Inventors: Koichi Takayanagi, Hideki Yamada, Shin-ichi Kazayama, Shin-ya Ohnuma
  • Halogenobenzyl aminopropionic acid derivatives
    Publication number: 20040102439
    Abstract: A halogenobenzylaminopropionic acid derivative represented by the following formula (1): 1
    Type: Application
    Filed: September 29, 2003
    Publication date: May 27, 2004
    Inventors: Koichi Takayanagi, Hideki Yamada, Shin-ichi Kazayama, Shin-ya Ohnuma