Abstract: An air-conditioning apparatus includes outdoor units each including a compressor and outdoor heat exchanger, refrigerant flowing through the outdoor units; an indoor unit including an indoor heat exchanger, a heat medium flowing through the indoor unit; relay devices to which the outdoor units are connected, and to which the indoor unit is connected, each relay device includes a heat medium heat exchanger that exchanges heat between the refrigerant and the heat medium; and a controller. The controller controls action of the outdoor units, the indoor unit, and the relay devices. The controller determines necessity for a defrosting operation; responsive the defrosting operation being necessary, compares an indoor unit total load with an outdoor unit total capacity; and controls an operating frequency of the compressor of an outdoor unit other than the outdoor unit on which the defrosting operation is to be performed to increase the outdoor unit total capacity.

Abstract: An air-conditioning apparatus according to the present disclosure includes a heat medium circulation circuit, a heat-source-side device, and a voltage drop device. In the heat medium circulation circuit, a pump, an indoor heat exchanger, and a flow control device are connected by pipes to circulate the heat medium. The pump sends a heat medium that contains water or brine and transfers heat. The indoor heat exchanger causes heat exchange to be performed between the heat medium and an indoor air in an air-conditioned space. The flow control device controls a flow rate of the heat medium in the indoor heat exchanger. The heat-source-side device heats or cools the heat medium before the heat medium is sent to the indoor heat exchanger. The voltage drop device reduces a voltage that is applied to the pump based on a value of a current that is supplied to the pump, in association with a flow rate of the heat medium in the heat medium circulation circuit.

Abstract: The present invention provides an improved encapsulated pancreatic islet. A formulation comprising a core covered with a five-layered membrane, wherein the core comprises one or more pancreatic islets; and the first, third, and fifth membranes from the inner side of the five-layered membrane contain alginic acid, and the second and fourth membranes from the inner side contain polyornithine.

Abstract: The present invention provides an improved method for producing pancreatic islet-containing capsules. A method for producing pancreatic islet-containing capsules, comprising the steps of: (a) preparing a sodium alginate solution A containing pancreatic islets at a concentration of 10,000 IEQ/mL or more; (b) adding the sodium alginate solution to a divalent cation solution dropwise, and collecting gelled particles; (c) adding the particles collected in step (b) to a poly-L-ornithine solution A, followed by stirring and then collecting particles; (d) adding the particles collected in step (c) to a sodium alginate solution B, followed by stirring and then collecting particles; and (e) adding the particles collected in step (d) to a sodium citrate solution, followed by stirring and then collecting particles.

Abstract: A refrigeration cycle apparatus includes; a refrigerant circuit in which a compressor, a heat-source-side heat exchanger, a first expansion device, a second expansion device, and a load-side heat exchanger are sequentially connected by refrigerant pipes and in which refrigerant is circulated; a controller that controls the refrigerant circuit; a bypass pipe extending from a liquid pipe between the first expansion device and the second expansion device toward a suction side of the compressor; a third expansion device provided at the bypass pipe to decompress the refrigerant that flows through the bypass pipe; and a refrigerant cooler provided at the bypass pipe and downstream of the third expansion device to cause heat exchange to be performed between the refrigerant decompressed by the third expansion device and heat generated from the controller.

Abstract: An air-conditioning apparatus includes: a heat-medium transfer device including a pump provided to transfer a heat medium that contains water or brine and transfers heat; a plurality of indoor units each of which includes an indoor heat exchanger provided to cause heat exchange to be performed between indoor air and the heat medium, and a flow control valve provided to adjust a flow rate of the heat medium that flows through the indoor heat exchanger, the plurality of indoor units being connected to the heat-medium transfer device by respective heat medium pipes; and a controller provided to control an opening degree of the flow control valve.

Abstract: An air-conditioning apparatus includes a refrigerant circuit, a heat medium circuit, and a controller. In the refrigerant circuit, a compressor, a heat-source-side heat exchanger, an expansion unit, and a load-side heat exchanger are connected by refrigerant pipes, and refrigerant flows. The heat-source-side heat exchanger causes heat exchange to be performed between the refrigerant and a heat-source heat medium. The load-side heat exchanger causes heat exchange to be performed between the refrigerant and a load heat medium, and refrigerant flows. In the heat medium circuit, a flow control valve that regulates the flow rate of the heat-source heat medium and the heat-source-side heat exchanger are connected by a heat medium pipe, and the heat-source heat medium flows. The controller includes a storage unit that stores data indicating a defined maximum flow rate and a defined minimum flow rate of the heat-source heat medium that flows in the heat medium circuit.

Abstract: An air-conditioning apparatus according to the present disclosure includes a heat medium circulation circuit, a heat-source-side device, and a voltage drop device. In the heat medium circulation circuit, a pump, an indoor heat exchanger, and a flow control device are connected by pipes to circulate the heat medium. The pump sends a heat medium that contains water or brine and transfers heat. The indoor heat exchanger causes heat exchange to be performed between the heat medium and an indoor air in an air-conditioned space. The flow control device controls a flow rate of the heat medium in the indoor heat exchanger. The heat-source-side device heats or cools the heat medium before the heat medium is sent to the indoor heat exchanger. The voltage drop device reduces a voltage that is applied to the pump based on a value of a current that is supplied to the pump, in association with a flow rate of the heat medium in the heat medium circulation circuit.

Abstract: The present invention relates to a water-based pigment dispersion containing a polymer dispersant and a pigment, the polymer dispersant being prepared by crosslinking a carboxy group-containing water-insoluble polymer (A) with a water-insoluble polyfunctional epoxy compound, in which carboxy groups of the water-insoluble polymer (A) are at least partially neutralized by an alkali metal compound, and the water-based pigment dispersion satisfies the following conditions 1 to 3. The water-based pigment dispersion of the present invention can exhibit excellent redispersibility capable of suppressing solidification of the pigment or the polymer in ink ejection nozzles and can ensure good storage stability under high-temperature conditions.

Abstract: An air-conditioning apparatus includes: a plurality of outdoor units each including a compressor and an outdoor heat exchanger, refrigerant flowing through the plurality of outdoor units; an indoor unit including an indoor heat exchanger, a heat medium flowing through the indoor unit; a plurality of relay devices to which the plurality of outdoor units are connected independently, and to which the indoor unit is connected, each of the plurality of relay devices including a heat medium heat exchanger configured to exchange heat between the refrigerant and the heat medium; and a controller configured to control action of the plurality of outdoor units, the indoor unit, and the plurality of relay devices, wherein the controller includes a defrost determination unit configured to determine necessity for a defrosting operation, a load determination unit configured to compare, in a case where the defrosting operation is necessary, an indoor unit total load with an outdoor unit total capacity, and an equipment contr

Abstract: An air-conditioning apparatus includes: a heat-medium transfer device including a pump provided to transfer a heat medium that contains water or brine and transfers heat; a plurality of indoor units each of which includes an indoor heat exchanger provided to cause heat exchange to be performed between indoor air and the heat medium, and a flow control valve provided to adjust a flow rate of the heat medium that flows through the indoor heat exchanger, the plurality of indoor units being connected to the heat-medium transfer device by respective heat medium pipes; and a controller provided to control an opening degree of the flow control valve.

Abstract: The present invention provides a method of producing a sheet-like pancreatic islet, comprising culturing an isolated pancreatic islet in a culture vessel, wherein a polypeptide comprising an EC1 domain of E-cadherin and having a binding ability to said E-cadherin is fixed on or applied to a surface of a solid phase, while being adhered to the solid phase surface for a period sufficient for the pancreatic islet to take a sheet-like form.

Abstract: An air-conditioning apparatus includes a heat source side unit configured to heat or cool a heat medium used as a heat-conveying medium, an air handling side heat exchanger that exchanges heat between outside air that is sent into a building and the heat medium, and an indoor side heat exchanger that exchanges heat between indoor air and the heat medium. The heat source side unit, the air handling side heat exchanger, and the indoor side heat exchanger are connected by piping to each other to form a heat medium cycle circuit through which the heat medium circulates. In the heat medium cycle circuit, a portion of the heat medium heated or cooled by the heat source side unit flows into the indoor side heat exchanger after having passed through the air handling side heat exchanger.

Abstract: The present invention relates to a water-based pigment dispersion having not only excellent storage stability capable of suppressing solidification of a pigment or the like in ink ejection nozzles, but also excellent ejection properties and fixing properties, while maintaining good water resistance of the pigment dispersion as an advantage attained by using the pigment therein.

Abstract: An air-conditioning apparatus includes a refrigerant circuit, a heat medium circuit, and a controller. In the refrigerant circuit, a compressor, a heat-source-side heat exchanger, an expansion unit, and a load-side heat exchanger are connected by refrigerant pipes, and refrigerant flows. The heat-source-side heat exchanger causes heat exchange to be performed between the refrigerant and a heat-source heat medium. The load-side heat exchanger causes heat exchange to be performed between the refrigerant and a load heat medium, and refrigerant flows. In the heat medium circuit, a flow control valve that regulates the flow rate of the heat-source heat medium and the heat-source-side heat exchanger are connected by a heat medium pipe, and the heat-source heat medium flows. The controller includes a storage unit that stores data indicating a defined maximum flow rate and a defined minimum flow rate of the heat-source heat medium that flows in the heat medium circuit.

Abstract: An air-conditioning apparatus includes a refrigeration cycle that includes an intermediate heat exchanger configured to exchange heat between a heat source side refrigerant and a heat medium different from the heat source side refrigerant. The apparatus further includes a heat medium circuit that includes at least one pump configured to circulate the heat medium in the intermediate heat exchanger. A controller in the apparatus further activates the pump to circulate the heat medium through the heat medium circuit when, during suspension of an air conditioning operation, the detected temperature of outdoor air is at or below a first predetermined temperature and a first predetermined period of time has elapsed since the pump was stopped.

Abstract: An air-conditioning apparatus includes two heat source units, each including a compressor, an outdoor heat exchanger functioning as an evaporator, an accumulator connected to a suction side of the compressor, and at least one of an outdoor air-sending device configured to supply air corresponding to a heat exchange target for refrigerant to the outdoor heat exchanger or a flow control device (bypass and expansion device for bypass) configured to regulate a flow rate of the refrigerant flowing through the outdoor heat exchanger. A controller is configured to control at least one of the outdoor air-sending device or the flow control device so that a suction quality of the compressor of an upper heat source unit installed on an upper side and a suction quality of the compressor of a lower heat source unit installed on a lower side become the same.

Abstract: The present invention relates to a water-based pigment dispersion containing a polymer dispersant and a pigment, the polymer dispersant being prepared by crosslinking a carboxy group-containing water-insoluble polymer (A) with a water-insoluble polyfunctional epoxy compound, in which carboxy groups of the water-insoluble polymer (A) are at least partially neutralized by an alkali metal compound, and the water-based pigment dispersion satisfies the following conditions 1 to 3. The water-based pigment dispersion of the present invention can exhibit excellent redispersibility capable of suppressing solidification of the pigment or the polymer in ink ejection nozzles and can ensure good storage stability under high-temperature conditions.