Patents by Inventor Koji Kabaya

Koji Kabaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions and therapeutic methods
    Patent number: 6071884
    Abstract: The present invention relates to a method for the treatment of thrombocytopenia wherein an effective amount of a compound represented by the formula (A) is administered to a patient: wherein R.sub.2 represents H or OH, X is an integer of 0-26 or R represents --(CH.sub.2).sub.7 CH.dbd.CH(CH.sub.2).sub.7 CH.sub.3, and R.sub.1 is a substituent defined by the following (a) to (d):(a) --CH.sub.2 (CH.sub.2).sub.y CH.sub.3,(b) --CH(OH)(CH.sub.2).sub.y CH.sub.3,(c) --CH(OH)(CH.sub.2).sub.y CH(CH.sub.3).sub.2, or(d) --CH.dbd.(CH)(CH.sub.2).sub.y CH.sub.3wherein Y is an integer of 5-17.
    Type: Grant
    Filed: October 28, 1998
    Date of Patent: June 6, 2000
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Yasuhiko Koezuka, Koji Kabaya, Kazuhiro Motoki
  • Method for accelerating marrow cell proliferation
    Patent number: 6017892
    Abstract: The present invention relates to a pharmaceutical composition (a marrow cell proliferation accelerator, a radioprotective agent, a therapeutic agent for thrombocytopenia) comprising a compound represented by the following formula (A), and to a therapeutic or prophylactic method (a method for accelerating marrow cell proliferation, a method for protecting human against radiation damage, a method for the treatment of thrombocytopenia) characterized in that an effective amount of a compound represented by the following formula (A) is administered to human: ##STR1## wherein R represents ##STR2## (wherein R.sub.2 represents H or OH, X is an integer of 0-26) or --(CH.sub.2).sub.7 CH.dbd.CH(CH.sub.2).sub.7 CH.sub.3, and R.sub.1 is one of the substituents defined by the following (a) to (d):--CH.sub.2 (CH.sub.2).sub.Y CH.sub.3, (a)--CH(OH)(CH.sub.2).sub.Y CH.sub.3, (b)--CH(OH)(CH.sub.2).sub.Y CH(CH.sub.3).sub.2, (c)and--CH.dbd.CH(CH.sub.2).sub.Y CH.sub.3 (d)(wherein Y is an integer of 5-17).
    Type: Grant
    Filed: June 23, 1997
    Date of Patent: January 25, 2000
    Assignee: Kiran Beer Kabushiki Kaisha
    Inventors: Yasuhiko Koezuka, Koji Kabaya, Kazuhiro Motoki
  • Treatment of radiation-damaged bone marrow using galactosyl ceramides
    Patent number: 5767092
    Abstract: The present invention relates to a pharmaceutical composition (a marrow cell proliferation accelerator, a radioprotective agent, a therapeutic agent for thrombocytopenia) comprising a compound represented by the following formula (A), and to a therapeutic or prophylactic method (a method for accelerating marrow cell proliferation, a method for protecting human against radiation damage, a method for the treatment of thrombocytopenia) characterized in that an effective amount of a compound represented by the following formula (A) is administered to human: ##STR1## wherein R.sub.2 represents ##STR2## 26) or --(CH.sub.2).sub.7 CH=CH(CH.sub.2).sub.7 CH.sub.3, and R.sub.1, is one of the substituents defined by the following (a) to (d):(a) --CH.sub.2 (CH.sub.2).sub.y CH.sub.3,(b) --CH(OH)(CH.sub.2).sub.y (CH.sub.3).sub.2, and(c) --CH(OH)(CH.sub.2).sub.y CH(CH.sub.3).sub.2, and(d) --CH=CH(CH.sub.2).sub.y CH.sub.3(wherein Y is an integer of 5-17).
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: June 16, 1998
    Assignee: Kirin Beer Kabushiki Kaisha
    Inventors: Yasuhiko Koezuka, Koji Kabaya, Kazuhiro Motoki