Patents by Inventor Koji Katsuki
Koji Katsuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10577637Abstract: An enzyme electrode includes an electrode, and a detection layer which contacts the electrode and contains a crosslinking agent, an electrically conductive macromolecule and an enzyme transferring and receiving electrons to and from the electrode and does not contain an electron transfer subunit.Type: GrantFiled: October 14, 2016Date of Patent: March 3, 2020Assignees: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Katsuki, Hisashi Kaneda, Junko Shimazaki
-
Patent number: 10451577Abstract: Provided is a measuring method using a biosensor, the method including: introducing a sample containing a substance to be measured into an electrochemical measurement cell, wherein the electrochemical measurement cell comprises: an insulating base plate; and an electrode system applying a first voltage to the electrode system; applying a second voltage to the electrode system; obtaining a first signal; obtaining a second signal; and correcting the second signal by the first signal, to determine the concentration of the substance to be measured in the sample.Type: GrantFiled: March 14, 2017Date of Patent: October 22, 2019Assignee: ARKRAY, Inc.Inventor: Koji Katsuki
-
Patent number: 10228341Abstract: A biosensor includes a plurality of electrodes including a working electrode, and a detection layer which is immobilized on the working electrode and contains a crosslinking agent, an electrically conductive macromolecule and an enzyme transferring and receiving electrons to and from the working electrode. The working electrode is in an open system.Type: GrantFiled: October 14, 2016Date of Patent: March 12, 2019Assignees: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Katsuki, Megumi Saeda, Junko Shimazaki
-
Patent number: 9976168Abstract: A method is provided for measuring a substance using a biosensor, the method comprising: introducing a sample containing the substance into an electrochemical measurement cell which comprises an insulating base plate; at least two electrodes formed on the insulating base plate; and a reagent layer that is disposed on at least one of the electrodes and comprises an oxidoreductase; applying a voltage to the electrodes; detecting a charge transfer limiting current which is generated due to the transfer of electrons from the substance in the sample to the electrode; and determining the concentration of the substance contained in the sample based on the charge transfer limiting current.Type: GrantFiled: August 7, 2014Date of Patent: May 22, 2018Assignees: ARKRAY, Inc., BioEngineering Laboratories, LLCInventor: Koji Katsuki
-
Publication number: 20180037927Abstract: A method of quantifying ammonia, the method includes performing a first reaction in which a test liquid containing ammonia is reacted with adenosine triphosphate and L-glutamic acid in the presence of glutamine synthetase to produce phosphoric acid, performing a second reaction in which the produced phosphoric acid is reacted with pyruvic acid in the presence of pyruvate oxidase, and measuring a component consumed or produced by the second reaction, to quantify ammonia, wherein a reaction to produce adenosine triphosphate from adenosine diphosphate mediated by pyruvate kinase is not carried out.Type: ApplicationFiled: August 2, 2017Publication date: February 8, 2018Applicant: ARKRAY, Inc.Inventors: Koji Katsuki, Takehiro Funamoto, Masaki Murakami
-
Patent number: 9795327Abstract: Disclosed is a measuring device for obtaining numerical information concerning a substance present in the interstitial subcutaneous fluid, the device being equipped with a sensor unit that outputs signals in accordance with the numerical information concerning the substance and an arithmetic unit (control unit) that receives the signals outputted from the sensor unit and arithmetically processes the signals. The sensor unit is equipped with a sensor, some of which is punctured into the skin. The arithmetic unit (control unit) has been disposed so as to be separate from the sensor unit.Type: GrantFiled: September 13, 2010Date of Patent: October 24, 2017Assignee: Arkray, Inc.Inventors: Tomohiro Shoshihara, Yasunori Shiraki, Koji Katsuki
-
Publication number: 20170269022Abstract: Provided is a measuring method using a biosensor, the method including: introducing a sample containing a substance to be measured into an electrochemical measurement cell, wherein the electrochemical measurement cell comprises: an insulating base plate; and an electrode system applying a first voltage to the electrode system; applying a second voltage to the electrode system; obtaining a first signal; obtaining a second signal; and correcting the second signal by the first signal, to determine the concentration of the substance to be measured in the sample.Type: ApplicationFiled: March 14, 2017Publication date: September 21, 2017Applicant: ARKRAY, Inc.Inventor: Koji Katsuki
-
Biosensor incorporating protein-immobilized membrane and method of immobilizing protein in biosensor
Patent number: 9702843Abstract: The present invention relates to a protein-immobilized membrane (14) including a cell membrane homologous layer (14A) and a protein (14B) immobilized to the cell membrane homologous layer (14A), where the protein contains cytochrome or a cytochrome complex. The present invention also relates to a method for forming a protein-immobilized membrane (14), and an enzyme-immobilized electrode and a biosensor (X1) provided with a protein-immobilized membrane (14). Preferably, the cell membrane homologous layer (14A) may contain a phospholipid polymer, and the protein (14B) may be CyGDH including an ? subunit having a glucose dehydrogenase activity and cytochrome C having a function of electron transfer.Type: GrantFiled: September 10, 2015Date of Patent: July 11, 2017Assignee: ARKRAY, Inc.Inventors: Koji Katsuki, Hideaki Yamaoka -
Patent number: 9651516Abstract: A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.Type: GrantFiled: January 8, 2016Date of Patent: May 16, 2017Assignee: ARKRAY, Inc.Inventors: Yasunori Shiraki, Koji Katsuki, Kazuya Iketani
-
Patent number: 9638657Abstract: A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.Type: GrantFiled: January 8, 2016Date of Patent: May 2, 2017Assignee: ARKRAY, Inc.Inventors: Yasunori Shiraki, Koji Katsuki, Kazuya Iketani
-
Publication number: 20170108459Abstract: A biosensor includes a plurality of electrodes including a working electrode, and a detection layer which is immobilized on the working electrode and contains a crosslinking agent, an electrically conductive macromolecule and an enzyme transferring and receiving electrons to and from the working electrode. The working electrode is in an open system.Type: ApplicationFiled: October 14, 2016Publication date: April 20, 2017Applicants: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Katsuki, Megumi Saeda, Junko Shimazaki
-
Publication number: 20170107555Abstract: An enzyme electrode includes an electrode, and a detection layer which contacts the electrode and contains a crosslinking agent, an electrically conductive macromolecule and an enzyme transferring and receiving electrons to and from the electrode and does not contain an electron transfer subunit.Type: ApplicationFiled: October 14, 2016Publication date: April 20, 2017Applicants: ARKRAY, Inc., Ultizyme International Ltd.Inventors: Koji Katsuki, Hisashi Kaneda, Junko Shimazaki
-
Publication number: 20160177365Abstract: A method is provided for measuring a substance using a biosensor, the method comprising: introducing a sample containing the substance into an electrochemical measurement cell which comprises an insulating base plate; at least two electrodes formed on the insulating base plate; and a reagent layer that is disposed on at least one of the electrodes and comprises an oxidoreductase; applying a voltage to the electrodes; detecting a charge transfer limiting current which is generated due to the transfer of electrons from the substance in the sample to the electrode; and determining the concentration of the substance contained in the sample based on the charge transfer limiting current.Type: ApplicationFiled: August 7, 2014Publication date: June 23, 2016Applicants: ARKRAY, Inc., BioEngineering Laboratories, LLCInventor: Koji Katsuki
-
Patent number: 9357960Abstract: A monitoring device which measures numerical value information on a subject substance in a body fluid has an electrochemical sensor including a sensor unit for detecting the subject substance which is used in the way of being embedded subcutaneously and generating an electric signal correlating to the numerical value information on the subject substance, and a temperature control unit which adjusts the detected ambient temperature as a temperature ambient to a sensor unit when detecting the subject substance so as to reach a target setting temperature when measuring the subject substance.Type: GrantFiled: December 4, 2014Date of Patent: June 7, 2016Assignee: ARKRAY, INC.Inventor: Koji Katsuki
-
Patent number: 9357957Abstract: A technique is provided, which makes it possible to continuously supply the driving electric power stably to a sensor even when the continuous monitoring period ranges over a long period of time when the numerical information is measured in relation to a test substance contained in a sample.Type: GrantFiled: January 17, 2011Date of Patent: June 7, 2016Assignee: ARKRAY, Inc.Inventors: Koji Katsuki, Yasunori Shiraki
-
Publication number: 20160123918Abstract: A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.Type: ApplicationFiled: January 8, 2016Publication date: May 5, 2016Applicant: ARKRAY, Inc.Inventors: Yasunori Shiraki, Koji Katsuki, Kazuya Iketani
-
Publication number: 20160123917Abstract: A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.Type: ApplicationFiled: January 8, 2016Publication date: May 5, 2016Applicant: ARKRAY, Inc.Inventors: Yasunori Shiraki, Koji Katsuki, Kazuya Iketani
-
Patent number: 9271671Abstract: A technique is provided, wherein any influence, which would be otherwise exerted on a reaction of an objective substance caused by a reagent enzyme by an interfering substance contained in a specimen, is suppressed in relation to an electrochemical sensor for measuring the objective substance contained in the specimen. A sensor comprises a substrate; a detecting unit which is provided on the substrate and which detects an objective substance; a filter which covers the detecting unit, which permits permeation of the objective substance on one hand, and which regulates permeation of an interfering substance contained in a sample on the other hand; and removing unit which removes the interfering substance adhered to the filter.Type: GrantFiled: March 28, 2011Date of Patent: March 1, 2016Assignee: ARKRAY, Inc.Inventors: Yasunori Shiraki, Koji Katsuki, Kazuya Iketani
-
BIOSENSOR INCORPORATING PROTEIN-IMMOBILIZED MEMBRANE AND METHOD OF IMMOBILIZING PROTEIN IN BIOSENSOR
Publication number: 20150377818Abstract: The present invention relates to a protein-immobilized membrane (14) including a cell membrane homologous layer (14A) and a protein (14B) immobilized to the cell membrane homologous layer (14A), where the protein contains cytochrome or a cytochrome complex. The present invention also relates to a method for forming a protein-immobilized membrane (14), and an enzyme-immobilized electrode and a biosensor (X1) provided with a protein-immobilized membrane (14). Preferably, the cell membrane homologous layer (14A) may contain a phospholipid polymer, and the protein (14B) may be CyGDH including an ? subunit having a glucose dehydrogenase activity and cytochrome C having a function of electron transfer.Type: ApplicationFiled: September 10, 2015Publication date: December 31, 2015Inventors: Koji Katsuki, Hideaki Yamaoka -
Patent number: 8996089Abstract: A continuous analysis apparatus capable of transmitting information about components in body fluid to another apparatus such as medicine dosing apparatus more correctly without giving a user displeasure. The continuous analysis apparatus according to the present invention includes a sensing unit 2 including a sensor that is held in subcutaneous tissue for obtaining information with respect to an objective substance in a sample; and a data holding unit 3 having a storage means for storing the information obtained from the sensor or data corresponding to the information, the sensing unit and the data holding unit having configuration so that they are separably joined to each other.Type: GrantFiled: June 25, 2010Date of Patent: March 31, 2015Assignee: ARKRAY, Inc.Inventors: Kazuya Iketani, Koji Katsuki, Yasuhide Kusaka