Abstract: A joint according to one aspect of the disclosure includes: a joint body having an input gear meshing with a speed reduction mechanism, the joint body receiving an output shaft of a motor detachably coupled to the joint body; a motor flange disposed between the speed reduction mechanism and the motor and rotatably supporting the joint body; and an intermediate flange connecting between the motor flange and the motor. At least one fixing member for fixing the joint body and the output shaft to each other is provided at at least one position in the joint body that overlaps with the intermediate flange as viewed from a radial direction. The intermediate flange is formed as an annulus surrounding the joint body by a plurality of split pieces that can be split in a circumferential direction.

Abstract: An object of the present invention is to provide a makeup brush bristle material and a makeup brush bristle material assembly, both made of synthetic resin, as well as a makeup brush using such bristle material or bristle material assembly, all suitable for applying both powder cosmetics and liquid cosmetics, or more specifically, offering good uptake and release properties with respect to powder or liquid cosmetics. As a solution, a makeup brush bristle material is provided that comprises S-twisted or Z-twisted core-sheath complex monofilaments whose core part is constituted by synthetic resin A and sheath part is constituted by synthetic resin B that differs in type from synthetic resin A, characterized in that the cross-section of the core-sheath complex monofilaments in the direction orthogonal to the axis of fiber has a cocoon shape.

Abstract: There is provided an electrochemical sensor, comprising: a working electrode; a counter electrode; and a base material supporting the working electrode and the counter electrode, wherein the working electrode is a chip-shaped electrode including a diamond film that causes a redox reaction on its surface when a predetermined voltage is applied in a state where a test sample exists between the working electrode and the counter electrode, and a support that comprises a material other than diamond and supports the diamond film, and the working electrode is mounted on the base material, with the support positioned on the base material side and at least a part of a side surface of the support exposed.

Abstract: In a hydraulic control device switchable between a first state in which a first oil is supplied from a first pump to a hydraulic operation part via a bypass valve and a second state in which the first oil supplied from the first pump is pressurized by using the second pump and the pressurized first oil is supplied, as a second oil, to the hydraulic operation part, control that adds a correction hydraulic pressure of a predetermined amount to the hydraulic pressure of the oil discharged from a valve for adjusting the pressure of the oil supplied to the hydraulic operation part is performed when the second state is switched to the first state due to a stop or a low rotation state of the second pump.

Abstract: The present invention is intended to provide: an anti-hCDCP1 antibody, which can be used as an active ingredient of anticancer agents having few side effects, etc.; and the aforementioned anti-hCDCP1 antibody that is formulated into ADC. Specifically, the present invention relates to an antibody that binds to human CDCP1 (CUB domain-containing protein 1), which has low binding property to human CD34-positive cells, or an antigen-binding fragment thereof.

Abstract: A multilayer tube is provided which includes a layer including a specific aliphatic polyamide composition and a layer including a semi-aromatic polyamide composition including a semi-aromatic polyamide with a specific structure, these layers being adjacent to each other, wherein the aliphatic polyamide composition includes an aliphatic polyamide having a specific ratio of the number of methylene groups to the number of amide groups, a polyamide having a specific difference in absolute value of solubility parameter SP from the aliphatic polyamide, and an elastomer polymer including a structural unit derived from an unsaturated compound having a carboxyl group and/or an acid anhydride group.

Abstract: The disclosure provides a hydraulic control device capable of suppressing an excessive increase in the rotation speed of a second pump and stabilizing the discharge pressure of the second pump. The target rotation speed of the second pump for making a pressure value of a first oil close to an estimated value of a pressure value of a third oil is calculated, and a feedback amount with respect to the target rotation speed is calculated by subtracting the estimated value of the pressure value of the third oil from the pressure value of the first oil detected by a hydraulic sensor. Time regions for performing calculation of the feedback amount include an update region in which the feedback amount with respect to the target rotation speed is updated, and a hold region in which update of the feedback amount with respect to the target rotation speed is temporarily stopped.

Abstract: Provided is a sensor that can appropriately sense the amount of abrasion powder (conductive substance) in a mechanical device of any size, and thereby to provide a sensor that can be generally used for preventive maintenance of any mechanical parts. The sensor includes a first electrode and a second electrode. A voltage is applied between the first electrode and the second electrode to accumulate conductive substance between the first and second electrodes in order to sense a decrease in electric resistance between the first and second electrodes. The distance between the first electrode and the second electrode is adjustable.

Abstract: Provided is a hydraulic control device in which in the rotation control of the second pump, the required discharge pressure of the second pump can be more reliably maintained below a predetermined pressure in the control that keeps the target rotation speed constant after the feedback control ends. In the rotation control of the second pump, in the control which keeps the target rotation speed constant after the feedback control ends, the rotation of the second pump is controlled by adding a predetermined addition rotation speed to the target rotation speed corresponding to the required discharge pressure. Since the required discharge pressure of the second pump can be maintained below a predetermined pressure in the fixed mode by the addition rotation speed, it can reliably obtain the effect of reducing the work load of the first pump and contribute to the improvement of the fuel efficiency of the vehicle.

Abstract: The disclosure provides a hydraulic control device. The operating/stopping of the second pump is determined based on a value of a difference between a reduced work rate of the first pump when the second pump is operated and a power consumption of the second pump. In a state where the second pump is stopped, the power consumption of the second pump is calculated based on an estimated value of a pressure of oil supplied to the hydraulic operation part and an estimated value of a pressure of oil supplied from the first pump to another hydraulic operation part or a lubrication target operating at a lower pressure than the hydraulic operation part. In a state where the second pump is operated, the power consumption of the second pump is calculated based on an actual rotation speed and an actual torque of the second pump.

Abstract: In a hydraulic control device switchable between a first state in which a first oil is supplied from a first pump to a hydraulic operation part via a bypass valve and a second state in which the first oil supplied from the first pump is pressurized by using the second pump and the pressurized first oil is supplied, as a second oil, to the hydraulic operation part, when the second pump is stopped in the second state, control that gradually decreases a target rotation speed of the second pump is performed, and rates at which the target rotation speed of the second pump decreases differ in a case where the second pump is stopped in an operation-allowed region and in a case where the second pump is stopped when the second pump is determined as in an operation-disallowed region.

Abstract: A conductive particle detecting device includes a plurality of electrodes, a permanent magnet, and a detecting circuit. The plurality of electrodes are arranged at intervals in a lubricant. The permanent magnet accumulates conductive particles in the lubricant between adjacent electrodes by a magnetic force. The detecting circuit detects target conductive particles based on electrical resistance between the adjacent electrodes. An attractive force of the permanent magnet acting on the conductive particles between the adjacent electrodes is set such that the lubricant remains as a non-conductive layer around fine-sized conductive particles having a smaller particle size than the target conductive particles.

Abstract: Provided is a headgear including first and second holding parts that respectively hold first and second cooling members. In a worn state, the first and second holding parts are respectively positioned laterally to left and right carotid arteries. The headgear includes a headgear main body to be worn on a head and a neck cover that covers a neck, the first and second holding parts are provided in the neck cover, the first holding part is a first pocket that stores the first cooling member, the second holding part is a second pocket that stores the second cooling member, and the headgear includes a coupling part that detachably couples a left end part and a right end part of the neck cover.

Abstract: A gear mechanism according to the invention includes a first shaft, a second shaft disposed at an angle with the first shaft, a first gear group including a plurality of first gears that transmit rotation of the first shaft to the second shaft; and a second gear group including a plurality of second gears that transmit, to an output side, rotation of the second shaft transmitted from the first shaft. A first second gear is situated closest to the second shaft among the plurality of second gears, a last second gear is situated closest to the output side among the plurality of second gears. A straight line that connects a rotation center of the first second gear and a rotation center of the last second gear form an angle with the first shaft when viewed in a direction along the second shaft.

Abstract: The present invention provides a therapeutic agent and a therapeutic method for hepatocellular carcinoma, etc., capable of exerting a more potent and sustained antitumor effect than existing multikinase inhibitors. The present invention is directed to a pharmaceutical combination for treating hepatocellular carcinoma, which is characterized by comprising lenvatinib or a prodrug thereof, or a pharmacologically acceptable salt thereof, or a hydrate or solvate thereof, and an antibody against human DLK-1, which has in vivo antitumor activity, or an antibody fragment derived from the antibody.

Abstract: A speed reducer according to the invention includes: a main speed reduction unit decelerating rotation from an input side and transmitting decelerated rotation to an output side; a fixed block coupled to the main speed reduction unit and rotatably supporting an input gear coupled to a rotary drive source; an output gear transmitting rotation of the input gear to an input side of the main speed reduction unit; and an intermediate gear meshing with the input gear and the output gear and rotatably supported by the fixed block.

Abstract: An aspect of the present invention provides a speed reducer including a supporting block, an input gear rotatably supported on the supporting block, an intermediate gear meshing with the input gear, an output gear meshing with the intermediate gear, and a gear position changing mechanism configured to change a position of the intermediate gear relative to the input and output gears.

Abstract: A piezoelectric vibrating device according to the present invention is provided with: a piezoelectric vibration plate having first and second driving electrodes respectively formed on main surfaces on both sides thereof, the piezoelectric vibration plate further having first and second mounting terminals that are respectively connected to the first and second driving electrodes. The piezoelectric vibrating device is also provided with first and second sealing members respectively joined to the main surfaces on both sides of the piezoelectric vibration plate in a manner that the first and second driving electrodes of the piezoelectric vibration plate are covered with these sealing members. At least one of the first and second sealing members includes a film made of a resin.

Abstract: A thermoplastic resin may have a structural unit of formula (1): wherein A1 to A8 are each independently ?CH— or ?N—, and at least one of A1 to A8 is ?N—. R1 to R8 are each independently a hydrogen atom, an alkyl group, an aryl group, a heteroaryl group, or the like, and at least two adjacent groups out of R1 to R8 may be bonded to each other to form a ring. R9 and R10 are each independently a direct bond or an optionally substituted alkylene group having 1 to 20 carbon atoms. X is an oxygen atom, a carbonyl group, or an optionally substituted amino group. And n is an integer of 0 to 5.