Patents by Inventor Koji Ohsumi

Koji Ohsumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS
    Publication number: 20200129458
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the present specification, or a salt thereof are useful for the prophylaxis or treatment of diabetes and obesity, and diseases related thereto.
    Type: Application
    Filed: December 27, 2019
    Publication date: April 30, 2020
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tomohiro FUJII, Koji Ohsumi, Seiji Kitajima, Yoshiro Kitahara
  • POLYMER BEAD
    Publication number: 20190367901
    Abstract: Beads containing a polymer containing uronic acid units having mercapto groups, in which the mercapto groups partly or entirely form disulfide bonds, are useful for encapsulating cells and microorganisms.
    Type: Application
    Filed: August 15, 2019
    Publication date: December 5, 2019
    Applicant: AJINOMOTO CO., INC.
    Inventors: Koji OHSUMI, Tomohiro FUJII
  • COMPOUND HAVING ENHANCING ACTIVITY FOR GLUCAGON-LIKE PEPTIDE-1 RECEPTOR ACTIONS
    Publication number: 20190022039
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the present specification, or a salt thereof are useful for the prophylaxis or treatment of diabetes and obesity, and diseases related thereto.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 24, 2019
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tomohiro FUJII, Koji OHSUMI, Seiji KITAJIMA, Yoshiro KITAHARA
  • Sweetness receptor antagonist
    Patent number: 9907766
    Abstract: Sweetness receptor antagonists represented by formula (I): wherein each symbol is described herein, are useful for the prophylaxis or treatment of metabolic syndrome, diabetes, obesity and the like.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: March 6, 2018
    Assignee: AJINOMOTO CO., INC.
    Inventors: Yoshiro Kitahara, Koji Ohsumi, Seiji Kitajima, Shimpei Ogawa
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9655879
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: November 6, 2015
    Date of Patent: May 23, 2017
    Assignee: EA Pharma Co., Ltd.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • SWEETNESS RECEPTOR ANTAGONIST
    Publication number: 20170101372
    Abstract: Sweetness receptor antagonists represented by formula (I): wherein each symbol is described herein, are useful for the prophylaxis or treatment of metabolic syndrome, diabetes, obesity and the like.
    Type: Application
    Filed: December 23, 2016
    Publication date: April 13, 2017
    Applicant: AJINOMOTO CO., INC.
    Inventors: Yoshiro KITAHARA, Koji OHSUMI, Seiji KITAJIMA, Shimpei OGAWA
  • HETEROCYCLIC SULFONAMIDE DERIVATIVE AND MEDICINE COMPRISING SAME
    Publication number: 20160332999
    Abstract: The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the DESCRIPTION, or a pharmaceutically acceptable salt thereof. The compound has a superior TRPA1 antagonist activity, and can provide a medicament useful for the prophylaxis or treatment of diseases involving TRPA1 antagonist and TRPA1.
    Type: Application
    Filed: July 28, 2016
    Publication date: November 17, 2016
    Applicant: EA PHARMA CO., LTD.
    Inventors: Kaori KOBAYASHI, Tamotsu SUZUKI, Mizuki KAWAHIRA, Tomohiro FUJII, Masayuki SUGIKI, Koji OHSUMI, Tatsuya OKUZUMI
  • Heterocyclic carboxylic acid ester derivative
    Patent number: 9346821
    Abstract: The present invention provides a blood glucose elevation inhibitor having a serine protease inhibitory action, which is a novel therapeutic or prophylactic agent for obesity. A compound represented by the following formula (I) wherein each symbol is as described in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: December 6, 2013
    Date of Patent: May 24, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Tamotsu Suzuki, Takahiro Koshiba, Munetaka Tokumasu, Koji Ohsumi
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20160058734
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: November 6, 2015
    Publication date: March 3, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takahiro KOSHIBA, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9227949
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: January 5, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • NOVEL TETRAHYDROPYRIDOPYRIMIDINONE DERIVATIVE
    Publication number: 20150368242
    Abstract: An object is to provide a novel compound having a higher MGAT2 inhibitory activity than conventional compounds. A compound represented by the following general formula (I) or a pharmaceutically acceptable salt thereof is provided.
    Type: Application
    Filed: August 28, 2015
    Publication date: December 24, 2015
    Applicant: Ajinomoto Co., Inc.
    Inventors: Tamotsu Suzuki, Hiroki Inoue, Kayo Matsumoto, Takahiro Koshiba, Koji Ohsumi, Hiroki Ozawa, Munetaka Tokumasu, Masatsugu Noguchi
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150313889
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: July 14, 2015
    Publication date: November 5, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, Osamu IKEHARA, Yuko KODAMA
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9115107
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: September 25, 2014
    Date of Patent: August 25, 2015
    Assignee: AJINOMOTO CO., INC.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 9024044
    Abstract: Compounds represented by the following formula (I), are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: May 5, 2015
    Assignee: Ajinomoto Co., Inc.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150099733
    Abstract: Compounds represented by the following formula (I); wherein each symbol is as defined in the specification, are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: December 11, 2014
    Publication date: April 9, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Takahiro KOSHIBA, Munetaka TOKUMASU, Taisuke ICHIMARU, Koji OHSUMI, Tadakiyo NAKAGAWA, Tatsuhiro YAMADA, Kayo MATSUMOTO, Tamotsu SUZUKI
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20150011511
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: September 25, 2014
    Publication date: January 8, 2015
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka TOKUMASU, Tamotsu SUZUKI, Takahiro KOSHIBA, Koji OHSUMI, OSAMU IKEHARA, Yuko KODAMA
  • Heteroarylcarboxylic acid ester derivative
    Patent number: 8877805
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Grant
    Filed: November 25, 2013
    Date of Patent: November 4, 2014
    Assignee: Ajinomoto Co., Inc.
    Inventors: Atsushi Konishi, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROCYCLIC CARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20140094489
    Abstract: The present invention provides a blood glucose elevation inhibitor having a serine protease inhibitory action, which is a novel therapeutic or prophylactic agent for obesity. A compound represented by the following formula (I) wherein each symbol is as described in the specification, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: December 6, 2013
    Publication date: April 3, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Tamotsu SUZUKI, Takahiro KOSHIBA, Munetaka TOKUMASU, Koji OHSUMI
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20140080790
    Abstract: Compounds represented by formula (I): wherein each symbol is as defined in the description, and pharmaceutically acceptable salts thereof are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: AJINOMOTO CO., INC.
    Inventors: Atsushi KONISHI, Munetaka Tokumasu, Tamotsu Suzuki, Takahiro Koshiba, Koji Ohsumi, Osamu Ikehara, Yuko Kodama
  • HETEROARYLCARBOXYLIC ACID ESTER DERIVATIVE
    Publication number: 20130338132
    Abstract: Compounds represented by the following formula (I), are useful as hyperglycemic inhibitors having a serine protease inhibitory action and as prophylactic or therapeutic drugs for diabetes.
    Type: Application
    Filed: June 14, 2012
    Publication date: December 19, 2013
    Applicant: Ajinomoto Co., Inc.
    Inventors: Takahiro Koshiba, Munetaka Tokumasu, Taisuke Ichimaru, Koji Ohsumi, Tadakiyo Nakagawa, Tatsuhiro Yamada, Kayo Matsumoto, Tamotsu Suzuki