Abstract: An object of the present invention is to provide an immunocompetent cell targeting mesothelin. An immunocompetent cell that expresses a cell surface molecule specifically recognizing human mesothelin, interleukin 7 (IL-7), and chemokine (C-C motif) ligand 19 (CCL19) is produced. It is preferred that: the cell surface molecule specifically recognizing human mesothelin should be chimeric antigen receptor (CAR) having single chain antibody, a transmembrane region, and a signaling region that induces the activation of the immunocompetent cell; and the heavy chain variable region and the light chain variable region should be connected via a peptide linker consisting of a 2- to 30-amino acid sequence.

Abstract: It is to provide an immunocompetent cell that expresses regulatory factors of immunocompetent cell immune function and possesses all of proliferative potential, viability, and the ability to accumulate a T cell, and an expression vector of regulatory factors of immune function for generating the immunocompetent cell. An immunocompetent cell expressing a cell surface molecule specifically recognizing a cancer antigen, interleukin 7 (IL-7), and CCL19 is generated. Preferably, the cell surface molecule specifically recognizing a cancer antigen is T cell receptor specifically recognizing the cancer antigen, and the immunocompetent cell is a T cell.

Abstract: An air conditioner that can have a higher efficiency, a lower power consumption, and a smaller size is disclosed. The air conditioner is for supplying air to a paint booth for painting a paint target. The air conditioner includes a housing that has an inlet and an outlet for air that is to be supplied, a humidifying means for spraying humidifying mist into the air taken in through the inlet, and a vaporizing means for vaporizing unvaporized humidifying mist contained in the air into which the humidifying mist was sprayed by the humidifying means by causing the unvaporized humidifying mist to come into contact with the air flowing through the vaporizing means. The air subjected to humidity adjustment by the humidifying means and the vaporizing means is supplied to the paint booth via the outlet.