Patents by Inventor Koji Sayama

Koji Sayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240053346
    Abstract: The present invention relates to providing a novel method for easily detecting tumor cells in a tissue derived from an organism. The present invention includes a fluorescent dye for detecting tumor cells in a tissue, including a compound that exhibits solvatochromism. The present invention also includes a method for detecting tumor cells or specifying a tumor removal area, including applying the fluorescent dye to staining of a tissue derived from an organism and to an organism.
    Type: Application
    Filed: September 6, 2021
    Publication date: February 15, 2024
    Inventors: Masamoto MURAKAMI, Ryosuke KAWAKAMI, Teruko TSUDA, Koji SAYAMA, Takeshi IMAMURA, Yosuke NIKO, Kazuki INOUE, Taku NAKAYAMA, Shingo HADANO, Shigeru WATANABE
  • Publication number: 20220290107
    Abstract: An object of the present invention is to provide a new means for suppressing inhibition of proliferation of keratinocytes even when the keratinocytes start to come into contact with each other. The present invention solves the above problem by culturing keratinocytes in contact with a common medium with fibroblasts treated with a composition containing a specific compound.
    Type: Application
    Filed: August 26, 2020
    Publication date: September 15, 2022
    Inventors: Jun Muto, Koji Sayama
  • Patent number: 6451584
    Abstract: A Lactobacillus bifidus growth promoting composition which significantly grows lactobacillus bifidus and does not produce any side effect such as diarrhea, and a blend comprising the above composition and other edible ingredients, and the composition comprises at least one oligosaccharide selected among lactulose, fructo-oligosaccharide, and galacto-oligosaccharide, and raffinose as the active ingredients.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: September 17, 2002
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Mamoru Tomita, Hirotoshi Hayasawa, Toshio Ohashi, Mitsunori Takase, Hirohiko Nakamura, Koji Sayama
  • Patent number: 6392094
    Abstract: A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer comprising an Na type or K type strongly acidic ion exchange resin; separating an effluent into at least a first fraction containing coloring matters, acidic amino acids and ashes, a second fraction containing neutral amino acids and saccharides, and a third fraction containing betaines; supplying the second fraction to a second-step resin layer comprising at least one resin selected from the group consisting of NH4 type, Ca type and Mg type strongly acidic ion exchange resins, and optionally further supplying it to a third-step resin layer comprising an Mg type or Ca type strongly acidic ion exchange resin different from the resin of the second-step resin layer, thereby recovering various kinds of amino acids contained in an effluent.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: May 21, 2002
    Assignee: Nippon Beet Sugar Mfg. Co., Ltd.
    Inventors: Takashi Kanno, Koji Sayama, Tsutomu Aritsuka, Hiroto Kikuchi
  • Publication number: 20020016502
    Abstract: A method for recovering amino acids, which comprises supplying a mixed solution containing inorganic acid salts, amino acids and non-electrolytes such as saccharides to a first-step resin layer comprising an Na type or K type strongly acidic ion exchange resin; separating an effluent into at least a first fraction containing coloring matters, acidic amino acids and ashes, a second fraction containing neutral amino acids and saccharides, and a third fraction containing betaines; supplying the second fraction to a second-step resin layer comprising at least one resin selected from the group consisting of NH4 type, Ca type and Mg type strongly acidic ion exchange resins, and optionally further supplying it to a third-step resin layer comprising an Mg type or Ca type strongly acidic ion exchange resin different from the resin of the second-step resin layer, thereby recovering various kinds of amino acids contained in an effluent.
    Type: Application
    Filed: June 19, 2001
    Publication date: February 7, 2002
    Applicant: NIPPON BEET SUGAR MFG. CO., LTD
    Inventors: Takashi Kanno, Koji Sayama, Tsutomu Aritsuka, Hiroto Kikuchi
  • Publication number: 20020015990
    Abstract: A Lactobacillus bifidus growth promoting composition which significantly grows lactobacillus bifidus and does not produce any side effect such as diarrhea, and a blend comprising the above composition and other edible ingredients, and the composition comprises at least one oligosaccharide selected among lactulose, fructo-oligosaccharide, and galacto-oligosaccharide, and raffinose as the active ingredients.
    Type: Application
    Filed: June 14, 1999
    Publication date: February 7, 2002
    Inventors: MAMORU TOMITA, HIROTOSHI HAYASAWA, TOSHIO OHASHI, MITSUNORI TAKASE, HIROHIKO NAKAMURA, KOJI SAYAMA