Patents by Inventor Kok-Hwee Ng
Kok-Hwee Ng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11751941Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: GrantFiled: January 12, 2022Date of Patent: September 12, 2023Assignee: St. Jude Medical, Inc.Inventor: Kok-Hwee Ng
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Publication number: 20230235377Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: ApplicationFiled: April 4, 2023Publication date: July 27, 2023Inventors: Adrian PONCE, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward MacLeod Perkins, Robert G. Waarts
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Patent number: 11603551Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: GrantFiled: December 2, 2020Date of Patent: March 14, 2023Assignee: STERITEC PRODUCTS MFG. CO., INC.Inventors: Adrian Ponce, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward MacLeod Perkins, Robert G. Waarts
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Publication number: 20220275423Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: ApplicationFiled: May 16, 2022Publication date: September 1, 2022Inventors: Adrian PONCE, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward MacLeod Perkins, Robert G. Waarts
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Publication number: 20220275422Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: ApplicationFiled: May 16, 2022Publication date: September 1, 2022Inventors: Adrian PONCE, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward MacLeod Perkins, Robert G. Waarts
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Publication number: 20220170067Abstract: A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.Type: ApplicationFiled: December 2, 2020Publication date: June 2, 2022Inventors: Adrian PONCE, Kok-Hwee Ng, Darshan Yeliyur Siddegowda, Jenna Zimmerman, Dat Nguyen, Mitchell London, Jake Douglas Knickerbocker, Edward MacLeod Perkins, Robert G. Waarts
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Publication number: 20220133404Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: ApplicationFiled: January 12, 2022Publication date: May 5, 2022Inventor: Kok-Hwee NG
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Patent number: 11241280Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: GrantFiled: June 26, 2018Date of Patent: February 8, 2022Assignee: ST. JUDE MEDICAL, INC.Inventor: Kok-Hwee Ng
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Patent number: 10179026Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: GrantFiled: November 10, 2014Date of Patent: January 15, 2019Assignee: ST. JUDE MEDICAL, INC.Inventor: Kok-Hwee Ng
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Publication number: 20180333204Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: ApplicationFiled: June 26, 2018Publication date: November 22, 2018Inventor: Kok-Hwee NG
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Publication number: 20150112329Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: ApplicationFiled: November 10, 2014Publication date: April 23, 2015Inventor: Kok-Hwee NG
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Patent number: 8909316Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: GrantFiled: June 6, 2011Date of Patent: December 9, 2014Assignee: St. Jude Medical, Cardiology Division, Inc.Inventor: Kok-Hwee Ng
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Publication number: 20120296232Abstract: Embodiments of the invention provide catheter devices for assessing transvascular denervation. A method of assessing denervation comprises: introducing intravascularly a catheter to a vessel of a patient, the catheter including one or more recording elements; performing a baseline recording of responses by supplying nerve stimulation to the vessel and recording responses of the vessel to the nerve stimulation; denervating at least some tissue proximate the vessel after performing the baseline recording; performing a post-denervation recording of responses, after the denervating, by supplying nerve stimulation to the vessel and recording responses of the vessel to the nerve stimulation; and assessing denervation of the vessel based on a comparison of the responses of the baseline recording and the responses of the post-denervation recording.Type: ApplicationFiled: June 6, 2011Publication date: November 22, 2012Applicant: ST. JUDE MEDICAL, INC.Inventor: Kok-Hwee NG
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Publication number: 20120296329Abstract: A catheter apparatus for assessing denervation comprises: an elongated catheter body; a deployable structure coupled to the catheter body, the deployable structure being deployable outwardly from and contractible inwardly toward the longitudinal axis of the catheter body; one or more ablation elements disposed on the deployable structure to move outwardly and inwardly with the deployable structure; one or more stimulation elements spaced from each other and disposed on the deployable structure to move with the deployable structure, the stimulation elements being powered to supply nerve stimulating signals to the vessel; and one or more recording elements spaced from each other and from the stimulation elements, the recording elements being disposed on the deployable structure to move with the deployable structure, the recording elements configured to record response of the vessel to the nerve stimulating signals.Type: ApplicationFiled: June 6, 2011Publication date: November 22, 2012Applicant: ST. JUDE MEDICAL, INC.Inventor: Kok-Hwee NG
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Publication number: 20090192566Abstract: This patent relates to a device for and method of stimulating the carotid sinus baroreceptors to achieve a restoration or resetting of baroreflex response and natural blood pressure modulation. The stimulation may consist of low amplitude, wide bandwidth signals that produce a stochastic resonance effect. The ultimate affect is blood pressure modulation within a reduced range including establishment of thresholds at which baroreceptors trigger normal central nervous system functions.Type: ApplicationFiled: January 25, 2008Publication date: July 30, 2009Applicant: STRYKER DEVELOPMENT LLCInventor: Kok-Hwee Ng
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Publication number: 20030078808Abstract: A system, computer readable medium and method for managing inventory of blood component collection soft goods and for preventing the use of quarantined soft goods. The system comprises a blood collection instrument, system computer, and a data interface. The blood component collection instrument collects a blood component from the blood component donor. The system computer is operably connected to the blood component collection instrument and runs a blood component collection application for at least a portion of a blood component collection process. The system computer is in data communication with a system database that has a blood component collection soft good inventory. The interface is operably connected to the system computer, and has a quarantine field for indicating that at least a portion of the blood component collection soft good inventory is quarantined.Type: ApplicationFiled: May 24, 2001Publication date: April 24, 2003Applicant: Baxter International Inc.Inventors: Kok-Hwee Ng , Grant Alexander Peterson , Ian Ford
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Publication number: 20030078805Abstract: A system, method and computer readable medium for managing a procedure in a blood component collection facility is disclosed. The system includes a donor identifier, an operator identifier a blood collection instrument, system computer, and a data interface. The donor identifier corresponds to a blood component donor and the operator identifier corresponds to the blood collection instrument operator. The blood component collection instrument collects a blood component from the blood component donor. The system computer is operably connected to the blood component collection instrument and includes a software application that defines at least a portion of a blood component collection process. The interface includes a reader and is operably connected to the system computer. The interface transmits the blood component donor identifier and the blood component collection instrument identifier to the system computer.Type: ApplicationFiled: May 24, 2001Publication date: April 24, 2003Applicant: Baxter International Inc.Inventors: Kok-Hwee Ng , Grant Alexander Peterson , Ian Ford
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Publication number: 20030069480Abstract: A system for networking the blood component collection facility is disclosed. The facility includes a plurality of independently operable blood component collection instruments. At least one of the blood component collection instrument is an existing collection instrument having a first communication protocol. The system comprises a system computer, a communication conduit, a second communication protocol, and a protocol converter. The system computer comprises a memory and a code segment which defines at least a portion of a blood component collection process. The communication conduit operably connects each of the plurality of blood component collection instruments to the system computer. The second communication protocol facilitates communication on the communication conduit between the system computer and each of the collection instruments.Type: ApplicationFiled: May 24, 2001Publication date: April 10, 2003Applicant: BAXTER INTERNATIONAL INC.Inventors: Kok-Hwee Ng , Ian Ford , Alfons Conley , Edward March
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Publication number: 20030040835Abstract: A system for managing inventory of blood component collection soft goods in a blood component collection facility is disclosed. The system comprises an operator identifier a blood collection instrument, system computer, and a data interface. The blood component collection instrument collects a blood component from the blood component donor. The system computer is operably connected to the blood component collection instrument and runs a blood component collection application for at least a portion of a blood component collection process. The system computer is in data communication with a system database having a blood component collection soft good inventory. The interface includes a reader and is operably connected to the system computer and receives the operator identifier and transmits the operator identifier to the system computer. The reader also receives separate input of the blood component soft good identifier and transmits the blood component soft good identifier to the system database.Type: ApplicationFiled: May 24, 2001Publication date: February 27, 2003Applicant: Baxter International Inc.Inventors: Kok-Hwee Ng , Alfons Conley , Edward March , Ian Ford
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Publication number: 20030040938Abstract: A system, computer readable medium and method for managing a procedure in a blood component collection facility is disclosed. The system comprises a blood component donor identifier corresponding to a blood component donor, an operator identifier corresponding to a blood component collection instrument operator, a blood component collection instrument, a system computer and an interface. The collection instrument collects a blood component from the blood component donor. The system computer is operably connected to the blood component collection instrument and runs a blood component collection application defining at least one step of a blood component collection process. The interface has a reader and is operably connected to the system computer. The interface and reader receives the blood component donor identifier and the operator identifier and transmit the operator identifier to the system computer proximate the performance of the at least one step of the blood component collection process.Type: ApplicationFiled: May 24, 2001Publication date: February 27, 2003Applicant: Baxter International Inc.Inventors: Kok-Hwee Ng , Grant Alexander Peterson , Winifred Shoults White , Ian Ford