Abstract: An antigen-binding protein, or an antigen-binding fragment thereof that binds to a Lewis X type glycan on SLAMF7, comprising (1) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GYTFTSYWIH; a VHCDR2 having the amino acid sequence EINPSNGRTNFNEKFKN and a VHCDR3 having the amino acid sequence VDYDEAY; and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence RSSKSLLHSNGITYLY, a VLCDR2 having the amino acid sequence QMSNLAS, and a VLCDR3 having the amino acid sequence AQNLELWT is provided. Methods of using the antibody for detecting or treating cancer, and a kit comprising the antibody are also provided.

Abstract: An antigen-binding protein, or an antigen-binding fragment thereof that binds to a Lewis X type glycan on SLAMF7, comprising (1) a heavy chain variable domain comprising a VHCDR1 having the amino acid sequence GYTFTSYWIH; a VHCDR2 having the amino acid sequence EINPSNGRTNFNEKFKN and a VHCDR3 having the amino acid sequence VDYDEAY; and (ii) a light chain variable domain comprising a VLCDR1 having the amino acid sequence RSSKSLLHSNGITYLY, a VLCDR2 having the amino acid sequence QMSNLAS, and a VLCDR3 having the amino acid sequence AQNLELWT is provided. Methods of using the antibody for detecting or treating cancer, and a kit comprising the antibody are also provided.

Abstract: An operations center (OC) (200) acts as an intermediary for securely and reliably transmitting a document (3) from a sender (100) to a next recipient (300) on a routing list. The OC (200) identifies (464) a recipient (300) from the next stage of the routing list and provides either the recipient's public key (404) or an escrow encryption key (406). The OC (200) optionally can authenticate the sender (100) and/or the recipient (300), thus increasing security.

Abstract: This method and apparatus extract symbolic high-level musical structure resembling that of a music score. Humming or the like is converted with this invention into a sequence of notes that represent the melody that the user (usually human, but potentially animal) is trying to express. These retrieved notes each contain information such as a pitch, the start time and duration and the series contains the relative order of each note. A possible application of the invention is a music retrieval system whereby humming forms the query to some search engine.