Patents by Inventor Kokichi Kikuchi

Kokichi Kikuchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYCLOSPORIN A-BINDING PROTEIN
    Publication number: 20110158908
    Abstract: Disclosed are: a composition and a method for the diagnosis and/or the treatment of a CSABP-related disease, the regulation of the proliferation of an RNA virus and the regulation of an RNA-metabolizing system, which targets a cyclosporin A-binding protein (CSABP); a method for the screening of a component that targets a CSABP; a composition and a method for the detection/inhibition of CsA, NS5B or cyclosphilin B by utilizing a CSABP; a promoter for a CSABP; a method for the screening of a substance capable of regulating the expression of a CSABP by utilizing the promoter; and a method for the determination of the occurrence or clinical stage of a CSABP-related disease.
    Type: Application
    Filed: August 22, 2008
    Publication date: June 30, 2011
    Applicant: Sapporo Medical University
    Inventors: Hiroeki Sahara, Yoko Mori, Nobuaki Takahashi, Noriyuki Sato, Fumio Sugawara, Kengo Sakaguchi, Kengo Morohashi, Kazuki Iwabata, Koichi Watashi, Kunitada Shimotohno, Kokichi Kikuchi, Wataru Tsutae, Hiroki Miyashita
  • Human gastric cancer antigen gene and gastric cancer antigen protein
    Patent number: 7030222
    Abstract: A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer antigen protein, introducing a selected cDNA clone into a cell of gastric cancer cell line that cannot induce gastric cancer antigen specific CTL so that the clone should be expressed in the cell, and selecting a transgenic cell that has acquired the ability to induce CTL. According to the present invention, there are provided a protein capable of inducing immune response against human gastric cancer, DNA encoding the protein, as well as vaccine for treatment and prevention of human gastric cancer, and agent for treatment and prevention of human gastric cancer.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: April 18, 2006
    Assignees: Ajinomoto Co., Inc.
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Toshihiko Torigoe, Hiroeki Sahara, Manabu Suzuki, Junji Hamuro
  • Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide
    Publication number: 20050208064
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Application
    Filed: February 7, 2005
    Publication date: September 22, 2005
    Applicants: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro
  • Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide
    Publication number: 20030186406
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Application
    Filed: January 8, 2002
    Publication date: October 2, 2003
    Applicant: AJINOMOTO CO., INC.
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro
  • Human gastric cancer antigen gene and gastric cancer antigen protein
    Publication number: 20020173642
    Abstract: A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer antigen protein, introducing a selected cDNA clone into a cell of gastric cancer cell line that cannot induce gastric cancer antigen specific CTL so that the clone should be expressed in the cell, and selecting a transgenic cell that has acquired the ability to induce CTL. According to the present invention, there are provided a protein capable of inducing immune response against human gastric cancer, DNA encoding the protein, as well as vaccine for treatment and prevention of human gastric cancer, and agent for treatment and prevention of human gastric cancer.
    Type: Application
    Filed: July 10, 2002
    Publication date: November 21, 2002
    Applicant: AJINOMOTO CO. INC
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Toshihiko Torigoe, Hiroeki Sahara, Manabu Suzuki, Junji Hamuro
  • Human gastric cancer antigen gene and gastric cancer antigen protein
    Patent number: 6444800
    Abstract: A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer antigen protein, introducing a selected cDNA clone into a cell of gastric cancer cell line that cannot induce gastric cancer antigen specific CTL so that the clone should be expressed in the cell, and selecting a transgenic cell that has acquired the ability to induce CTL. According to the present invention, there are provided a protein capable of inducing immune response against human gastric cancer, DNA encoding the protein, as well as vaccine for treatment and prevention of human gastric cancer, and agent for treatment and prevention of human gastric cancer.
    Type: Grant
    Filed: July 7, 1999
    Date of Patent: September 3, 2002
    Assignees: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Toshihiko Torigoe, Hiroeki Sahara, Manabu Suzuki, Junji Hamuro
  • Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide
    Patent number: 6368852
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Grant
    Filed: June 24, 1998
    Date of Patent: April 9, 2002
    Assignees: Ajinomoto Co., Inc.
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro
  • Peptide capable of inducing immune response to human gastric cancer and agent for preventing or treating human gastric cancer, containing the peptide
    Patent number: 5837248
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: November 17, 1998
    Assignees: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro