Abstract: Provided is a means capable of predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, by a simple and minimally invasive method. A method for predicting a formation of thrombus or a risk thereof in a medical device performing blood circulation by a pump, wherein it is predicted that thrombus is formed or there is a risk thereof in the medical device when a concentration or expression amount of ADAM28 in a body fluid sample collected from a subject wearing the medical device is elevated compared with a reference value.

Abstract: A centrifugal pump (10) includes a housing (26), an impeller (28) that is rotatably disposed inside the housing (26), a shaft (62) that is provided at a center rotational axis of the impeller (28), and bearings (70) that pivotally support the shaft ends (66). At least one of the shaft ends (66) has surface roughness Ra equal to or less than 0.21 ?m and/or surface roughness Ry equal to or less than 1.49 ?m.

Abstract: A centrifugal pump (10) includes a housing (26), an impeller (28) that is rotatably disposed inside the housing (26), a shaft (62) that has spherical surface-shaped shaft ends (66) at both ends in an axial direction, and bearings (70) that have spherical surface-shaped bearing surfaces (73) respectively and pivotally supporting the shaft ends (66). In at least one of the bearings (70) disposed on both sides of the shaft (62) in the axial direction, a ratio of a radius of curvature of the shaft end (66) with respect to a radius of curvature of the bearing surface (73) of the bearing (70) is equal to or less than 85%.

Abstract: A cardiac function measuring system 200 includes a flowmeter 70 that measures a flow rate waveform of blood from a human body while the blood is circulating outside the body in an extracorporeal circulator. A control unit 100 acquires a pulsation waveform 62 (waveform 60) which is a flow rate fluctuation waveform of blood included in a flow rate waveform measured by the flowmeter 70. A display unit 30 displays a pulsation waveform indicating a cardiac function of a human body in response to a command from the control unit 100.

Abstract: A centrifugal blood pump reliably prevents blood from entering between an impeller and a shaft member. Pump 1 includes a pump chamber 24, a housing 2 including a blood inlet 25 and a blood outlet 26, an impeller 3 as a centrifugal force applying member rotatably encased in the pump chamber 24 and applying a centrifugal force to the blood Q by the rotation of the impeller 3. A support mechanism 4 supports impeller 3 rotatably with respect to the housing 2. The support mechanism 4 includes a rod-shaped shaft member 41 disposed at the rotation center of the impeller 3. Shaft member 41 and the impeller 3 are formed integrally with each other, as by insert molding.

Abstract: A centrifugal pump (10) includes a housing (26), an impeller (28) that is rotatably disposed inside the housing (26), a shaft (62) that is provided at a center rotational axis of the impeller (28), and bearings (70) that pivotally support the shaft ends (66). At least one of the shaft ends (66) has surface roughness Ra equal to or less than 0.21 ?m and/or surface roughness Ry equal to or less than 1.49 ?m.

Abstract: A centrifugal pump (10) includes a housing (26), an impeller (28) that is rotatably disposed inside the housing (26), a shaft (62) that has spherical surface-shaped shaft ends (66) at both ends in an axial direction, and bearings (70) that have spherical surface-shaped bearing surfaces (73) respectively and pivotally supporting the shaft ends (66). In at least one of the bearings (70) disposed on both sides of the shaft (62) in the axial direction, a ratio of a radius of curvature of the shaft end (66) with respect to a radius of curvature of the bearing surface (73) of the bearing (70) is equal to or less than 85%.

Abstract: A centrifugal blood pump reliably prevents blood from entering between an impeller and a shaft member. Pump 1 includes a pump chamber 24, a housing 2 including a blood inlet 25 and a blood outlet 26, an impeller 3 as a centrifugal force applying member rotatably encased in the pump chamber 24 and applying a centrifugal force to the blood Q by the rotation of the impeller 3. A support mechanism 4 supports impeller 3 rotatably with respect to the housing 2. The support mechanism 4 includes a rod-shaped shaft member 41 disposed at the rotation center of the impeller 3. Shaft member 41 and the impeller 3 are formed integrally with each other, as by insert molding.