Patents by Inventor Kong-Hong Andy Choo

Kong-Hong Andy Choo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acid molecule
    Patent number: 7186550
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian an artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Grant
    Filed: December 2, 2000
    Date of Patent: March 6, 2007
    Assignee: Murdoch Childrens Research Institute
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla
  • Neocentromere-based mini-chromosomes or artificial chromosomes
    Publication number: 20040081982
    Abstract: The present invention is directed generally to a defined or isolated nucleic acid molecule encompassing a neocentreomere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic mini-chromosomes and artificial chromosomes including mammalian (e.g. human) and non-mammalian mini-chromosomes and artificial chromosomes. The present invention further provides a telomere-associated chromosome truncation (TACT) approach to develop mini-chromosomes, but is not limited to this approach. It is directed to any truncation approach that produces a neocentromere-containing mini-chromosome, or any transfection approach using cloned or pre-fabricated DNA that provides neocentromere function in the construction of artificial chromosome. Such mini-chromosomes and artificial chromosomes are useful in a range of genetic therapies.
    Type: Application
    Filed: June 17, 2003
    Publication date: April 29, 2004
    Inventors: Kong-Hong Andy Choo, Lee Hwa Wong, Richard Eric Saffrey
  • Novel nucleic acid molecule
    Publication number: 20030096398
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian an artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Application
    Filed: December 2, 2000
    Publication date: May 22, 2003
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla
  • Nucleic acid molecules comprising a neocentromere
    Patent number: 6265211
    Abstract: The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: July 24, 2001
    Assignee: AMRAD Operations Pty. Ltd.
    Inventors: Kong-Hong Andy Choo, Desiree Du Sart, Michael Robert Cancilla