Patents by Inventor Konkal-Matt R. Prasad

Konkal-Matt R. Prasad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of adeno-associated virus (AAV) to deliver genes
    Patent number: 6485976
    Abstract: This invention pertains to a method of protecting pancreatic &bgr;-cells from immune system-mediated cell damage through transduction of the cells with an adeno-associated viral vector encoding cytoprotective genes. These protected cells are suitable for transplantation into mammals and will be protected from rejection by the host. The method also may be used to protect pancreatic islet &bgr;-cells in situ for the primary prevention of immune-mediated destruction which leads to Type 1 diabetes. Pancreatic &bgr;-cells may be transduced with AAV vectors according to the invention for in vivo or ex vivo gene therapy.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: November 26, 2002
    Assignee: City of Hope
    Inventors: Jerry L. Nadler, David Bleich, Konkal-Matt R. Prasad