Patents by Inventor Konrad Huppi

Konrad Huppi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of diagnosing and treating cancer using B-catenin splice variants
    Patent number: 10000813
    Abstract: The invention relates to method and compositions for treating and diagnosing cancer, in particular ?-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: June 19, 2018
    Assignee: The United States of America, as represented by the Secretary, Department of Health & Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • METHOD OF DIAGNOSING AND TREATING CANCER USING B-CATENIN SPLICE VARIANTS
    Publication number: 20120294929
    Abstract: The invention relates to method and compositions for treating and diagnosing cancer, in particular ?-catenin related cancers. In general, the methods include administering RNAi constructs. The invention further relates to methods of identifying CTNNB1 related cancer therapeutics.
    Type: Application
    Filed: January 3, 2012
    Publication date: November 22, 2012
    Applicant: Health & Human Services - NIH
    Inventors: Mark J. Roth, Konrad Huppi
  • Method of diagnosing and treating cancer using B-catenin splice variants
    Patent number: 8110352
    Abstract: The invention relates to method of diagnosing and treating cancer, in particular ?-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: February 7, 2012
    Assignee: The United States of America as represented by the Secretary, Department of Health & Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • METHOD OF DIAGNOSING AND TREATING CANCER USING B-CATENIN SPLICE VARIANTS
    Publication number: 20090111762
    Abstract: The invention relates to method of diagnosing and treating cancer, in particular ?-catenin related cancers. The invention further relates to methods of identifying CTNNB1 related cancer CTNNB1 therapeutics.
    Type: Application
    Filed: February 10, 2006
    Publication date: April 30, 2009
    Applicant: Govt. of the US, as represented by the Secretary, Department of Health and Human Services
    Inventors: Mark J. Roth, Konrad Huppi
  • Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
    Patent number: 5272057
    Abstract: The invention relates to a method for detecting the presence of a DNA polymorphism associated with predisposition for certain cancers in a human. This method involves analyzing the human chromosome 13 using a hybridization probe which will hybridize to the gene for human poly (ADP-ribose) polymerase wherein the probe is capable of identifying the DNA polymorphism.
    Type: Grant
    Filed: October 14, 1988
    Date of Patent: December 21, 1993
    Assignee: Georgetown University
    Inventors: Mark E. Smulson, Kishor Bhatia, Konrad Huppi