Patents by Inventor Konrad Krolikiewicz

Konrad Krolikiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Multiply-substituted tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
    Publication number: 20050222154
    Abstract: The invention relates to multiply-substituted tetrahydronaphthalene derivatives of formula (I) process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: October 12, 2004
    Publication date: October 6, 2005
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
    Publication number: 20050209324
    Abstract: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: October 12, 2004
    Publication date: September 22, 2005
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
    Publication number: 20050171109
    Abstract: The invention relates to tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: October 12, 2004
    Publication date: August 4, 2005
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors
    Publication number: 20050165050
    Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I and a process for their production, and their use as inflammation inhibitors.
    Type: Application
    Filed: February 17, 2005
    Publication date: July 28, 2005
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Markus Berger, Hartmut Rehwinkel, Konrad Krolikiewicz, Werner Skuballa, Heike Schaecke, Arndt. Schottelius
  • Substituted pentanols, a process for their production and their use as anti-inflammatory agents
    Publication number: 20050143415
    Abstract: The invention relates to substituted pentanols, a process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: October 5, 2004
    Publication date: June 30, 2005
    Inventors: Stefan Jaroch, Stefan Baeurle, Markus Berger, Konrad Krolikiewicz, Duy Nguyen, Hartmut Rehwinkel, Norbert Schmees, Werner Skuballa, Heike Schaecke
  • Rearranged pentanols, a process for their production and their use as anti-inflammatory agents
    Publication number: 20050131226
    Abstract: The invention relates to the compounds of formula I, a process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: October 8, 2004
    Publication date: June 16, 2005
    Inventors: Hartmut Rehwinkel, Stefan Baeurle, Markus Berger, Norbert Schmees, Heike Schaecke, Konrad Krolikiewicz, Anne Mengel, Duy Nguyen, Stefan Jaroch, Werner Skuballa
  • Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors
    Patent number: 6897224
    Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I a process for their production and their use as inflammation inhibitors.
    Type: Grant
    Filed: April 2, 2003
    Date of Patent: May 24, 2005
    Assignee: Schering AG
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Markus Berger, Hartmut Rehwinkel, Konrad Krolikiewicz, Werner Skuballa, Heike Schäecke, Arndt. J. G. Schottelius
  • Heterocyclically-substituted pentanol derivatives, process for their production and their use as anti-inflammatory agents
    Publication number: 20050090559
    Abstract: The invention relates to pentanol derivatives of general formula I that are substituted by quinazoline, quinoxaline, cinnoline, indazole, phthalazine, naphthyridine, benzothiazole, dihydroindolone, dihydroisoindolone, benzimidazole or indole, a process for their production and their use as anti-inflammatory agents.
    Type: Application
    Filed: July 1, 2004
    Publication date: April 28, 2005
    Inventors: Markus Berger, Stefan Baeurle, Hartmut Rehwinkel, Norbert Schmees, Heike Schaecke, Manfred Lehmann, Konrad Krolikiewicz, Arndt Schottelius, Duy Nguyen, Anne Mengel, Stefan Jaroch
  • Nonsteroidal antiinflammatory agents
    Publication number: 20040254249
    Abstract: Compounds of Formula 1 1
    Type: Application
    Filed: June 24, 2004
    Publication date: December 16, 2004
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius
  • Nonsteroidal antiinflammatory agents
    Patent number: 6777409
    Abstract: The compound of formula 1 useful in the treatment of inflammation.
    Type: Grant
    Filed: July 27, 2001
    Date of Patent: August 17, 2004
    Assignee: Schering Aktiengesellschaft Patents
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndt Schottelius
  • Quinoline and isoquinoline derivatives, a process for their production and their use as inflammation inhibitors
    Publication number: 20040116694
    Abstract: The invention relates to quinoline and isoquinoline derivatives of general formula I 1
    Type: Application
    Filed: April 2, 2003
    Publication date: June 17, 2004
    Applicant: Schering AG
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Markus Berger, Harmut Rehwinkel, Konrad Krolikiewicz, Werner Skuballa, Heike Schaecke, Arndt J.G. Schottelius
  • Nonsteroidal antiinflammatory agents
    Publication number: 20020077356
    Abstract: The compound of formula 1 1
    Type: Application
    Filed: July 27, 2001
    Publication date: June 20, 2002
    Inventors: Stefan Jaroch, Manfred Lehmann, Norbert Schmees, Bernd Buchmann, Harmur Rehwinkel, Peter Droescher, Werner Skuballa, Konrad Krolikiewicz, Hartwig Hennekes, Heike Schaecke, Arndr Schottelius
  • Nonsteroidal anti-inflammatory agents
    Patent number: 6323199
    Abstract: This invention describes the use of the compounds of general formula I in which A, B, A, Ar, R1, R2 and R3 have the meaning that is indicated in more detail in the description, for the production of pharmaceutical agents with anti-inflammatory action. The compounds of general formula I show a clear dissociation between anti-inflammatory and metabolic action.
    Type: Grant
    Filed: November 24, 1999
    Date of Patent: November 27, 2001
    Assignee: Schering Aktiengesellschaft
    Inventors: Manfred Lehmann, Konrad Krolikiewicz, Werner Skuballa, Peter Strehlke, Frank Kalkbrenner, Roland Ekerdt, Claudia Giesen
  • Process for preparing nucleosides with unprotected sugars
    Patent number: 5750676
    Abstract: A novel process for nucleoside synthesis, which process comprises reacting the free sugar with heterocyclic bases in the presence of silylating agents in an inert solvent containing a Lewis acid.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: May 12, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Helmut Vorbruggen, Konrad Krolikiewicz, Barbel Bennua-Skalmowski
  • Process for the production of 2-fluoropurine derivatives
    Patent number: 5696255
    Abstract: This invention relates to a process for the production of 2-fluoropurine derivatives from 2-aminopurine derivatives, which are reacted in HF/pyridine or HF/pyridine/H.sub.2 O in the presence of a nitrite.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: December 9, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Helmut Vorbruggen, Konrad Krolikiewicz, Randolph C. Wirsching, John G. Bauman
  • Process for the production of bicyclo(3.3.0)octane-3,7-dione-2-carboxylic acid esters
    Patent number: 4960907
    Abstract: The invention relates to a process for the production of D,L-bicyclo[3.3.0]octane-3,7-dione-2-carboxylic acid esters of Formula I ##STR1## wherein R is methyl or ethyl, andZ isoxygen or the ketal residue ##STR2## wherein X means ethylene, trimethylene or 2,2-dimethyltrimethylene, characterized in that D,L-bicyclo[3.3.0]octane-3,7-dione-2,6-dicarboxylic acid esters of Formula II ##STR3## wherein R has the meanings given above, are partially saponified and decarboxylated in an aqueous or water-containing medium in the presence of acids, and are optionally selectively ketalized.
    Type: Grant
    Filed: July 24, 1989
    Date of Patent: October 2, 1990
    Assignee: Schering Aktiengesellschaft
    Inventors: Helmut Vorbrueggen, Konrad Krolikiewicz