Patents by Inventor Konstantin Lyashchenko

Konstantin Lyashchenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Assay for detecting tuberculosis in nonhuman primates
    Patent number: 8128941
    Abstract: Systems, methods, and compositions for a diagnostic method for detecting TB in non-human primates that is easy to use, sensitive, and specific. The method utilizes recombinant mycobacterial antigens, such as polyfusion proteins. The method utilizes an antigen-antibody-antigen arrangement to detect TB infection in nonhuman primates. The method can detect IgM antibodies to TB, in addition to IgG antibodies, providing ability to detect TB earlier in nonhuman primate TB infection as compared to conventional TB tests.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: March 6, 2012
    Assignee: Chembio Diagnostic Systems, Inc.
    Inventors: Konstantin Lyashchenko, Javanbakhsh Esfandiari, Candace McCombs
  • Universal rapid test and method for detection of tuberculosis in multiple host species
    Patent number: 7192721
    Abstract: A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus includes a test site having a mycobacterial antigen cocktail comprising ESAT-6/CFP10 and 16 kDa/MPB83 polyfusion antigens, and a tracer having the ESAT-6/CFP10 polyfusion antigen and MPB83 antigen conjugated to latex or colloidal gold. The universal test apparatus is effective across genuses, families and orders of non-primate mammals.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: March 20, 2007
    Assignee: Chembio Diagnostic Systems, Inc.
    Inventors: Javanbakhsh Esfandiari, Konstantin Lyashchenko
  • UNIVERSAL RAPID TEST AND METHOD FOR DETECTION OF TUBERCULOSIS IN MULTIPLE HOST SPECIES
    Publication number: 20070054335
    Abstract: A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus includes a test site having a mycobacterial antigen cocktail comprising ESAT-6/CFP10 and 16 kDa/MPB83 polyfusion antigens, and a tracer having the ESAT-6/CFP10 polyfusion antigen and MPB83 antigen conjugated to latex or colloidal gold. The universal test apparatus is effective across genuses, families and orders of non-primate mammals.
    Type: Application
    Filed: September 8, 2005
    Publication date: March 8, 2007
    Inventors: Javanbakhsh Esfandiari, Konstantin Lyashchenko
  • Assay for detecting tuberculosis in nonhuman primates
    Publication number: 20060057621
    Abstract: Systems, methods, and compositions for a diagnostic method for detecting TB in non-human primates that is easy to use, sensitive, and specific. The method utilizes recombinant mycobacterial antigens, such as polyfusion proteins. The method utilizes an antigen-antibody-antigen arrangement to detect TB infection in nonhuman primates. The method can detect IgM antibodies to TB, in addition to IgG antibodies, providing ability to detect TB earlier in nonhuman primate TB infection as compared to conventional TB tests.
    Type: Application
    Filed: August 26, 2005
    Publication date: March 16, 2006
    Inventors: Konstantin Lyashchenko, Javanbakhsh Esfandiari, Candace McCombs