Patents by Inventor Konstantinos Drosatos

Konstantinos Drosatos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of Treating Diabetic Cardiomyopathy by Inhibiting GLUT1
    Publication number: 20240108614
    Abstract: Provided herein are methods for treating diabetic cardiomyopathy in a patient in need thereof, such as a patient diagnosed with type 1 or type 2 diabetes. The methods generally include administering a therapeutically effective amount of one or more glucose transporter isoform 1 (GLUT1) inhibitors to the patient. Exemplary GLUT1 inhibitors include STF-31, WZB117, phloretin, and BAY-876.
    Type: Application
    Filed: October 3, 2023
    Publication date: April 4, 2024
    Applicant: University of Cincinnati
    Inventors: Konstantinos Drosatos, Md Sobuj Mia
  • Methods for Treating and Preventing Cardiac Dysfunction in Septic Shock
    Publication number: 20140045758
    Abstract: Cardiac dysfunction during sepsis is due, at least in part, to cardiac energy deficiency. It has been discovered that lipopolysaccharide (LPS)-mediated cardiac dysfunction is prevented or treated by treatments that improve FA oxidation (FAO), despite the persistence of inflammation. The present invention relates to methods for increasing or maintaining cardiac function in a subject, by administering to the subject a therapeutically effective amount of an agent that increases fatty acid oxidation in the heart.
    Type: Application
    Filed: February 21, 2012
    Publication date: February 13, 2014
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Ira J. Goldberg, Konstantinos Drosatos