Abstract: A photonic chip has at least one input waveguide, at least one output waveguide, one of at least one Mach-Zehnder interferometer and at least one resonator, and a one-sided optical port enabling in and out coupling of light where the input waveguide begins and the output waveguide ends.

Abstract: A photonic chip has at least one input waveguide, at least one output waveguide, one of at least one Mach-Zehnder interferometer and at least one resonator, and a one-sided optical port enabling in and out coupling of light where the input waveguide begins and the output waveguide ends.

Abstract: Novel photoresist materials, which can be photolithographically processed in biocompatible conditions are presented in this invention. Suitable lithographic scheme for the use of these and analogous resists for biomolecule layer patterning on solid substrates are also described. The processes described enable micropatterning of more than two different proteins on solid substrates without denaturation of the proteins. The preferred resist materials are based on (meth)acrylate copolymers that contain at least one acid cleavable ester group and at least one hydrophilic group such as an alcoholic or a carboxylic group.

Abstract: This invention provides a method for the fabrication of surfaces of high surface area ratio on polymeric/plastic materials, and their application in the control of the wetting properties of surfaces, of the transport of liquids on such fabricated surfaces, or of the separation of liquids in microchannels of said surfaces. The fabrication of surfaces of high surface area ratio comprises the following steps: (a) selection of a polymer/plastic layer which contains two or more components differing in their plasma etching behaviour (b) exposure of said polymer/plastic layer to an etching plasma to provide selective removal of one polymer component versus a second plasma-resistant component so as to result in a randomly rough columnar-like surface. In addition, exposure of the said surface to an oxidizing plasma or to a fluorocarbon. depositing plasma renders the surface fully hydrophilic or en super-hydrophobic, respectively.

Abstract: An integrated optoelectronic silicon biosensor that can detect biomolecules by the change of the optical coupling between the integrated light source and the integrated detector that is caused by the binding of the appropriately labeled analytes onto the recognition molecules, that have been previously immobilized onto the integrated optical fiber that connects the optical source with the detector. The device contains the optoelectronic silicon chip and its biological activation. The optoelectronic chip is realized following integrated circuits fabrication methods so as the light source, the detector and the optical fiber, that optically couples the light source with the detector, to be monolithically integrated on the same silicon substrate. The biological activation of the chip is performed through physicochemical modification of the chip surface in order to permit immobilization of the recognition biomolecules onto the optical fiber surface.

Abstract: Novel photoresist materials, which can be photolithographically processed in biocompatible conditions are presented in this invention. Suitable lithographic scheme for the use of these and analogous resists for biomolecule layer patterning on solid substrates are also described. The processes described enable micropatterning of more than two different proteins on solid substrates without denaturation of the proteins. The preferred resist materials are based on (meth)acrylate copolymers that contain at least one acid cleavable ester group and at least one hydrophilic group such as an alcoholic or a carboxylic group.

Abstract: An integrated optoelectronic silicon biosensor that can detect biomolecules by the change of the optical coupling between the integrated light source and the integrated detector that is caused by the binding of the appropriately labeled analytes onto the recognition molecules, that have been previously immobilized onto the integrated optical fiber that connects the optical source with the detector. The device contains the optoelectronic silicon chip and its biological activation. The optoelectronic chip is realized following integrated circuits fabrication methods so as the light source, the detector and the optical fiber, that optically couples the light source with the detector, to be monolithically integrated on the same silicon substrate. The biological activation of the chip is performed through physicochemical modification of the chip surface in order to permit immobilization of the recognition biomolecules onto the optical fiber surface.