Patents by Inventor Konstantinos Papas

Konstantinos Papas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous emulsions of lipophile solubilized with vitamin E TPGS and linoleic acid
    Patent number: 7790190
    Abstract: Disclosed herein is an aqueous emulsion. The lipid phase of the emulsion includes a blend of a therapeutically effective concentration of a lipophile, a concentration of Vitamin E TPGS, and a concentration of linoleic acid. The presence of linoleic acid increases the solubilizing affect of Vitamin E TPGS on the lipophile and thus reduces the amount of Vitamin E TPGS that would otherwise be required in the aqueous emulsion.
    Type: Grant
    Filed: March 20, 2004
    Date of Patent: September 7, 2010
    Assignee: Yasoo Health, Inc.
    Inventors: Andreas M. Papas, Konstantinos A. Papas, Howard K. Hobbs, Warren Hopkins, William A. Clark
  • Vitamin E TPGS fluid concentrate comprising a low percentage of water
    Publication number: 20060088558
    Abstract: A liquid Vitamin E TPGS concentrate composition is provided, the concentrate having a significantly higher percentage of TPGS per unit volume than traditional liquid TPGS formulations while providing the TPGS in a liquid form that can be used in softgels or mixed with water to produce desired concentrations for commercial use in supplements, beverages, pharmaceutical preparations, etc.
    Type: Application
    Filed: October 26, 2005
    Publication date: April 27, 2006
    Inventors: Robert Jandzinski, Andreas Papas, Konstantinos Papas, Constantinos Neophytou
  • Composition and method for improving pancreatic islet cell survival
    Publication number: 20050276794
    Abstract: The invention provides a composition for protecting islet cells during isolation and transplantation, as well as a method for increasing survival of islets and islet cells during harvest from the donor pancreas, isolation and culture, transportation, and transplantation into the recipient. The composition provides at least one Vitamin E homolog that, when combined with cell culture media, increases islet cell survival.
    Type: Application
    Filed: June 9, 2005
    Publication date: December 15, 2005
    Inventors: Klearchos Papas, Andreas Papas, Konstantinos Papas
  • Bioavailable nutritional supplement and method of treatment of malabsorption
    Publication number: 20050209315
    Abstract: The invention relates to novel vitamin compositions having increased absorption and bioavailability. Vitamin E compositions are provided, for example, having biologically significant amounts of one or more vitamin E homologues in an aqueous formulation. Also provided is a method for preparing aqueous formulations of lipophilic nutrients.
    Type: Application
    Filed: January 19, 2005
    Publication date: September 22, 2005
    Inventors: Andreas Papas, Konstantinos Papas
  • Aqueous emulsions of lipophile solubilized with vitamin E TPGS and linoleic acid
    Publication number: 20050208082
    Abstract: Disclosed herein is an aqueous emulsion. The lipid phase of the emulsion includes a blend of a therapeutically effective concentration of a lipophile, a concentration of Vitamin E TPGS, and a concentration of linoleic acid. The presence of linoleic acid increases the solubilizing affect of Vitamin E TPGS on the lipophile and thus reduces the amount of Vitamin E TPGS that would otherwise be required in the aqueous emulsion.
    Type: Application
    Filed: March 20, 2004
    Publication date: September 22, 2005
    Inventors: Andreas Papas, Konstantinos Papas, Howard Hobbs, Warren Hopkins, William Clark
  • Composition for treating inflammatory bowel disease
    Publication number: 20050107465
    Abstract: A method for reducing inflammation in inflammatory bowel disease is disclosed. The method comprises reducing the expression of endothelial cell adhesion molecules in the vasculature of the bowel wall by administering a therapeutic dosage of an effective amount of a blend of vitamin E TPGS and gamma-tocopherol. Gamma-tocopherol is also useful when used alone in the invention. The reduction in endothelial cell adhesion molecules is due to the deactivation of endothelial NF?-B by the composition.
    Type: Application
    Filed: June 18, 2004
    Publication date: May 19, 2005
    Inventors: Andreas Papas, Konstantinos Papas, J. Alexander
  • Gamma-tocopherol and gamma-tocotrienol therapy for multiple sclerosis
    Publication number: 20050080109
    Abstract: A therapy for decreasing the rate of demyelination in multiple sclerosis comprising administering gamma-tocopherol and/or gamma-tocotrienol in a therapeutically effective dosage. The therapeutic dosage is high, between about 800 mg to about 10 grams of gamma-tocopherol and between about 50 mg to about 5 grams of gamma-tocotrienol per day.
    Type: Application
    Filed: October 12, 2004
    Publication date: April 14, 2005
    Inventors: Andreas Papas, Konstantinos Papas
  • Alpha-tocopherol treatment for cystic fibrosis
    Publication number: 20050074445
    Abstract: Disclosed herein is an aqueous emulsion of alpha-tocopherol and preferably other forms of vitamin E, coenzyme Q10, beta-carotene, vitamin D, and vitamin K useful for treating complications of cystic fibrosis. The aqueous emulsion improves malabsorption and immunity against infection, and reduces oxidative stress and respiratory complications in cystic fibrosis.
    Type: Application
    Filed: September 20, 2004
    Publication date: April 7, 2005
    Inventors: Andreas Papas, Konstantinos Papas, Warren Hopkins, William Clark
  • Coenzyme Q10 treatment for cystic fibrosis
    Publication number: 20050074444
    Abstract: Disclosed herein is an aqueous emulsion of coenzyme Q10 and preferably vitamin E, beta-carotene, vitamin D, and vitamin K useful for treating complications of cystic fibrosis. The aqueous emulsion improves malabsorption and immunity against infection, and reduces oxidative stress and respiratory complications in cystic fibrosis.
    Type: Application
    Filed: September 20, 2004
    Publication date: April 7, 2005
    Inventors: Andreas Papas, Konstantinos Papas, Warren Hopkins, William Clark
  • Treatment for diabetic microvascular and macrovascular complications
    Publication number: 20050074447
    Abstract: Disclosed herein is a method of preventing or retarding the progression of diabetic microvascular and macrovascular complications by chronically administering a therapeutically effective amount of gamma-tocopherol to a diabetic patient. It is further disclosed that a greater cytoprotective benefit is provided by administering a blend of gamma-tocotrienol and alpha-tocotrienol.
    Type: Application
    Filed: October 1, 2004
    Publication date: April 7, 2005
    Inventors: Andreas Papas, Konstantinos Papas, Klearchos Papas
  • Gamma-tocopherol treatment for cystic fibrosis
    Publication number: 20050074446
    Abstract: Disclosed herein is an aqueous emulsion of gamma-tocopherol and preferably other forms of vitamin E, coenzyme Q10, beta-carotene, vitamin D, and vitamin K useful for treating complications of cystic fibrosis. The aqueous emulsion improves malabsorption and immunity against infection, and reduces oxidative stress and respiratory complications in cystic fibrosis.
    Type: Application
    Filed: September 20, 2004
    Publication date: April 7, 2005
    Inventors: Andreas Papas, Konstantinos Papas, Warren Hopkins, William Clark