Patents by Inventor Konstantinos Rampalakos

Konstantinos Rampalakos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIHYDRO-CYCLOPENTA-ISOQUINOLINE SULFONAMIDES DERIVATIVES
    Publication number: 20240092773
    Abstract: The present invention relates to dihydro-cyclopenta-isoquinoline derivatives of formula (I): processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular, disorders caused by the interaction of IgE with the Fc?RI receptor.
    Type: Application
    Filed: December 22, 2020
    Publication date: March 21, 2024
    Inventors: Timothy John NORMAN, Zhaoning ZHU, Selvaratnam SUGANTHAN, Konstantinos RAMPALAKO, James MADDEN, Jag Paul HEER, Richard Jeremy FRANKLIN, Rickki Lee CONNELLY, Thierry DEMAUDE, Gregory William HASLETT, Benedicte LALLEMAND, Nathaniel Julius Thomas MONCK, Julian Hugh ROWLEY, Giancarlo TRANI
  • DIHYDROCYCLOPENTA-ISOQUINOLINE-SULFONAMIDE DERIVATIVES COMPOUNDS
    Publication number: 20230303517
    Abstract: The present invention relates to dihydrocyclopenta-isoquinoline-sulfonamide derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the Fc?RI receptor.
    Type: Application
    Filed: December 22, 2020
    Publication date: September 28, 2023
    Inventors: Timothy John NORMAN, Douglas BYRNE, Julian Hugh ROWLEY, Giancarlo TRANI, Konstantinos RAMPALAKOS, Nathaniel Julius Thomas MONCK, Benedicte LALLEMAND, Gregory William HASLETT, Rickki Lee CONNELLY, Jag Paul HEER, James MADDEN, Oliver PHILPS, Selvaratnam SUGANTHAN, Zeshan YOUSUF, Richard John MEARS
  • DIFLUOROCYCLOHEXYL DERIVATIVES AS IL-17 MODULATORS
    Publication number: 20230271951
    Abstract: A series of substituted 4,4-difluorocyclohexyl derivatives as defined herein, being potent modulators of human IL-17 activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including inflammatory and autoimmune disorders.
    Type: Application
    Filed: April 6, 2021
    Publication date: August 31, 2023
    Inventors: Prafulkumar Tulshibhai CHOVATIA, Anne Marie FOLEY, Gregory William HASLETT, Martin Clive HUTCHINGS, James Andrew JOHNSON, Fabien Claude LECOMTE, Nathaniel Julius Thomas MONCK, Joanna Rachel QUINCEY, Konstantinos RAMPALAKOS, James Thomas REUBERSON, Adam Peter SMALLEY, Giancarlo TRANI, Darshan Gunvant VAIDYA
  • Thiophene derivatives for the treatment of disorders caused by IgE
    Publication number: 20220332709
    Abstract: Thiophene derivatives of formula (I) and a pharmaceutically acceptable salt thereof are provided. These compounds have utility for the treatment or prevention of disorders caused by IgE, such as allergy, type 1 hypersensitivity or familiar sinus inflammation.
    Type: Application
    Filed: June 20, 2019
    Publication date: October 20, 2022
    Inventors: Pfrafulkumar Tulshibhai Chovatia, Rickki Lee Connelly, Richard Jeremy Franklin, Gregory William Haslett, Alistair James Henry, James Madden, Judi Charlotte Neuss, Timothy John Norman, Oliver Philps, William Ross Pitt, Konstantinos Rampalakos, Matthew Duncan Selby, Suganthan Selvaratnam, Giancarlo Trani, Zhaoning Zhu