Patents by Inventor Konstantinos Tsioris

Konstantinos Tsioris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210290829
    Abstract: A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.
    Type: Application
    Filed: February 11, 2021
    Publication date: September 23, 2021
    Inventors: David L. Kaplan, Konstantinos Tsioris, Fiorenzo G. Omenetto, Eleanor M. Pritchard
  • Patent number: 10933173
    Abstract: A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: March 2, 2021
    Assignee: Trustees of Tufts College
    Inventors: David L. Kaplan, Konstantinos Tsioris, Fiorenzo G. Omenetto, Eleanor M. Pritchard
  • Patent number: 9603243
    Abstract: The invention relates to silk electronic components and methods for fabricating the same. The silk electronic components can be used as novel devices, such as implantable bioelectric and/or biophotonic devices, biosensors, surveillance devices, invisible cloaks, electromagnetic concentrators or antennas.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: March 21, 2017
    Assignees: TUFTS UNIVERSITY, TRUSTEES OF BOSTON UNIVERSITY
    Inventors: David Kaplan, Fiorenzo Omenetto, Hu Tao, Richard Averitt, Andrew Strikwerda, Xin Zhang, Konstantinos Tsioris
  • Publication number: 20130338632
    Abstract: A microneedle or microneedle device includes a microneedle body extending from a base to a penetrating tip formed from a silk fibroin based material, which is easy to fabricate and highly biocompatible. The microneedle device can include one or more microneedles mounted to a substrate. The silk fibroin can include active agents to be transported into or across biological barriers such as skin, tissue and cell membranes. The silk fibroin microneedles can be fully or partially biodegradable and/or bioerodible. The silk fibroin is highly stable, affords room temperature storage and is implantable. The silk fibroin structure can be modulated to control the rate of active agent delivery.
    Type: Application
    Filed: October 19, 2011
    Publication date: December 19, 2013
    Applicant: TRUSTEES OF TUFTS COLLEGE
    Inventors: David L. Kaplan, Konstantinos Tsioris, Fiorenzo G. Omenetto, Eleanor M. Pritchard
  • Publication number: 20130240251
    Abstract: The invention relates to silk electronic components and methods for fabricating the same. The silk electronic components can be used as novel devices, such as implantable bioelectric and/or biophotonic devices, biosensors, surveillance devices, invisible cloaks, electromagnetic concentrators or antennas.
    Type: Application
    Filed: April 12, 2011
    Publication date: September 19, 2013
    Applicants: TRUSTEES OF BOSTON UNIVERSITY, TUFTS UNIVERSITY
    Inventors: David Kaplan, Fiorenzo Omenetto, Jason Amsden, Hu Tao, Richard Averitt, Andrew Strikwerda, Xin Zhang, Konstantinos Tsioris