Abstract: The present invention relates to a solid phase cosmetic composition comprising a freeze-dried component of a composition comprising a functional component and a basic amino acid. A solid phase component according to the present invention has excellent re-dissolvability, and exhibits insignificant changes in the hardness and pH of the composition for dissolving the solid component even after re-dissolution, and thus a cosmetic having excellent stability can be provided.

Abstract: The present invention relates to a powder complex for cosmetics and a cosmetic composition comprising thereof. More specifically, the present invention relates to a powder complex for cosmetics for improving easy-to-clean of the cosmetic powder with water repellency and a cosmetic composition comprising thereof. The powder complex for cosmetic of the present invention has a technical feature that the amphipathic copolymer having a specific structure is adsorbed on the surface of the hydrophobized powder. The cosmetic composition according to the present invention can exhibit an excellent effect of cleaning, with excellent makeup durability.

Abstract: The present disclosure relates to an apparatus and a process which can continuously produce microneedles using a conveyor system and decomposition or vacuum. By using the microneedle production method and apparatus according to the present disclosure, continuous mass production of microneedles is available, and therefore it is possible to reduce the input of manpower and produce a large amount of products compared to the conventional production method.

Abstract: The present invention relates to a cosmetic composition comprising a eutectic mixture containing: an amino acid, an alpha-hydroxy acid, and water; or two types of amino acids. The cosmetic comprises either an amino acid and an alpha-hydroxy acid or two types of amino acids in the form of a eutectic mixture. Thus, a cosmetic composition with excellent skin penetration effect even under weakly acidic or neutral pH conditions, which causes less irritation, can be provided, wherein the cosmetic composition provides excellent keratin exfoliation, reduces the number of pores, enhances skin elasticity, and promotes skin regeneration while having excellent low-temperature stability.

Abstract: The present invention relates to a superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body for magnetic resonance imaging and magnetic thermotherapy. According to the present invention, a superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body which has target directionality and a high density of ultrafine gold nanoparticles uniformly coupled to the surface of protein nanoparticles can be fabricated with neither a separate surface stabilization process nor a separate target directionality conferring process. Hence, the superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body according to the present invention is superior to conventional gold nanoparticles in terms of biocompatibility and has excellent target directionality as well as being identified to have a temperature elevation potential in an alternating magnetic field and a functionality as a T2-MRI contrast medium thanks to the superparamagnetism property of the ultrafine gold nanoparticles.

Abstract: The present invention relates to a powder complex for cosmetics and a cosmetic composition comprising thereof. More specifically, the present invention relates to a powder complex for cosmetics for improving easy-to-clean of the cosmetic powder with water repellency and a cosmetic composition comprising thereof. The powder complex for cosmetic of the present invention has a technical feature that the amphipathic copolymer having a specific structure is adsorbed on the surface of the hydrophobized powder. The cosmetic composition according to the present invention can exhibit an excellent effect of cleaning, with excellent makeup durability.

Abstract: The present disclosure relates to an apparatus and a process which can continuously produce microneedles using a conveyor system and decomposition or vacuum. By using the microneedle production method and apparatus according to the present disclosure, continuous mass production of microneedles is available, and therefore it is possible to reduce the input of manpower and produce a large amount of products compared to the conventional production method.

Abstract: The present invention relates to a superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body for magnetic resonance imaging and magnetic thermotherapy. According to the present invention, a superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body which has target directionality and a high density of ultrafine gold nanoparticles uniformly coupled to the surface of protein nanoparticles can be fabricated with neither a separate surface stabilization process nor a separate target directionality conferring process. Hence, the superparamagnetic gold nanoparticle cluster-protein nanoparticle fusion body according to the present invention is superior to conventional gold nanoparticles in terms of biocompatibility and has excellent target directionality as well as being identified to have a temperature elevation potential in an alternating magnetic field and a functionality as a T2-MRI contrast medium thanks to the superparamagnetism property of the ultrafine gold nanoparticles.

Abstract: The present invention relates to a recombinant self-assembled protein comprising a target-oriented peptide and a use thereof The recombinant self-assembled protein according to the present invention, comprising a target-oriented peptide, does not require an additional process for providing target-orientedness, and is thus capable of delivering a desired drug to a target tissue or target cell without using additives, such as chemical binders or stabilizers; therefore, the protein can be used for photothermal therapy, drug delivery, imaging, or the like. In particular, according to the present invention, it is possible to prepare gold-protein nanoparticle fusions in which uniform high-density gold nanoparticles having target-orientedness are bound to protein surfaces, without an additional process of surface stabilization or process for providing target-orientedness.

Abstract: The present invention relates to a recombinant self-assembled protein comprising a target-oriented peptide and a use thereof. The recombinant self-assembled protein according to the present invention, comprising a target-oriented peptide, does not require an additional process for providing target-orientedness, and is thus capable of delivering a desired drug to a target tissue or target cell without using additives, such as chemical binders or stabilizers; therefore, the protein can be used for photothermal therapy, drug delivery, imaging, or the like. In particular, according to the present invention, it is possible to prepare gold-protein nanoparticle fusions in which uniform high-density gold nanoparticles having target-orientedness are bound to protein surfaces, without an additional process of surface stabilization or process for providing target-orientedness.

Abstract: The present invention relates to a recombinant self-assembled protein comprising a target-oriented peptide and a use thereof. The recombinant self-assembled protein according to the present invention, comprising a target-oriented peptide, does not require an additional process for providing target-orientedness, and is thus capable of delivering a desired drug to a target tissue or target cell without using additives, such as chemical binders or stabilizers; therefore, the protein can be used for photothermal therapy, drug delivery, imaging, or the like. In particular, according to the present invention, it is to possible to prepare gold-protein nanoparticle fusions in which uniform high-density gold nanoparticles having target-orientedness are bound to protein surfaces, without an additional process of surface stabilization or process for providing target-orientedness.