Patents by Inventor Koreaki Imura

Koreaki Imura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210147400
    Abstract: Provided is a novel process for producing a (2S)-2-[(1H-pyrazol-1-yl)methyl]-1,3-oxazinane derivative. More specifically, provided is a process for producing a (2S)-2-[(1H-pyrazol-1-yl)methyl]-1,3-oxazinane derivative represented by formula (1): the process comprising reacting 3-aminopropan-1-ol with glyoxylic acid.
    Type: Application
    Filed: July 11, 2018
    Publication date: May 20, 2021
    Applicant: TAISHO PHARMACEUTICAL CO., LTD.
    Inventors: Takaaki MATSUBARA, Hiroki URABE, Ryo SUZUKI, Aya FUTAMURA, Ryo KINOSHITA, Nobutaka HATTORI, Hideaki TABUSE, Koreaki IMURA, Norikazu OTAKE
  • Patent number: 8822674
    Abstract: A highly stable crystal of (1S)-1,5-anhydro-1-[5-(4-{(1E)-4-[(1-{[2-(dimethylamino)ethyl]amino}-2-methyl-1-oxopropan-2-yl)amino]-3,3-dimethyl-4-oxobut-1-en-1-yl}benzyl)-2-methoxy-4-(propan-2-yl)phenyl]-D-glucitol, and a process for producing the crystal are provided. Specifically, an ethanolate having the following physical properties, and a plurality of other crystal forms transformed from the ethanolate are provided: (a) Having peaks at 2?=5.9 degrees, 17.1 degrees, 17.6 degrees and 21.5 degrees in X-ray powder diffraction (Cu—K?); (b) Showing characteristic absorption bands at 3538 cm?1, 3357 cm?1, 2964 cm?1, 1673 cm?1, 1634 cm?1 and 1505 cm?1 in an infrared absorption spectrum; and (c) Having a melting point in a vicinity of 111° C.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: September 2, 2014
    Assignee: Taisho Pharmaceutical Co., Ltd
    Inventors: Yoshihiro Kimura, Koreaki Imura, Naoto Osaki, Ayumi Matsushima
  • Publication number: 20130144050
    Abstract: A highly stable crystal of (1S)-1,5-anhydro-1-[5-(4-{(1E)-4-[(1-{[2-(dimethylamino)ethyl]amino}-2-methyl-1-oxopropan-2-yl)amino]-3,3-dimethyl-4-oxobut-1-en-1-yl}benzyl)-2-methoxy-4-(propan-2-yl)phenyl]-D-glucitol, and a process for producing the crystal are provided. Specifically, an ethanolate having the following physical properties, and a plurality of other crystal forms transformed from the ethanolate are provided: (a) Having peaks at 2?=5.9 degrees, 17.1 degrees, 17.6 degrees and 21.5 degrees in X-ray powder diffraction (Cu—K?); (b) Showing characteristic absorption bands at 3538 cm?1, 3357 cm?1, 2964 cm?1, 1673 cm?1, 1634 cm?1 and 1505 cm?1 in an infrared absorption spectrum; and (c) Having a melting point in a vicinity of 111° C.
    Type: Application
    Filed: August 19, 2011
    Publication date: June 6, 2013
    Applicant: TAISHO PHARMACEUTICAL CO., LTD.
    Inventors: Yoshihiro Kimura, Koreaki Imura, Naoto Osaki, Ayumi Matsushima
  • Patent number: 7238719
    Abstract: Disclosed is a process for efficiently producing a compound represented by formula (I): wherein R1 represents aryl, amino, alkyl, or alkoxy; R2 represents a protective group of the carboxylic acid; and R3 represents an alkali metal, a hydrogen atom, alkyl, aryl, alkylsulfonyl, arylsulfonyl, or trialkylsilyl. This process is characterized by reacting a compound of formula (II) with a compound of formula (III) in the presence of a transition metal compound.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: July 3, 2007
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Shohei Yasuda, Koreaki Imura, Yumiko Okada, Shinichiro Tsujiyama
  • Publication number: 20050080270
    Abstract: Disclosed is a process for efficiently producing a compound represented by formula (I): wherein R1 represents aryl, amino, alkyl, or alkoxy; R2 represents a protective group of the carboxylic acid; and R3 represents an alkali metal, a hydrogen atom, alkyl, aryl, alkylsulfonyl, arylsulfonyl, or trialkylsilyl. This process is characterized by reacting a compound of formula (II) with a compound of formula (III) in the presence of a transition metal compound.
    Type: Application
    Filed: February 3, 2003
    Publication date: April 14, 2005
    Inventors: Shohei Yasuda, Koreaki Imura, Yumiko Okada, Shinichiro Tsujiyama