Patents by Inventor Koren Holland Deckman

Koren Holland Deckman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation and characterization of a single mitochondrion
    Patent number: 9217740
    Abstract: A method for identifying mitochondrial heteroplasmy within eukaryotic cells is provided. This method includes means for isolating and capturing a single mitochondrion from at least one eukaryotic cell, wherein the means for isolating and capturing a single mitochondrion further includes optical tweezers or a similar optical technology; means for analyzing the isolated and captured mitochondrion, wherein the means for analyzing the isolated and captured mitochondrion further includes a DNA amplification system and a sequencing system for amplifying and sequencing DNA extracted from the mitochondrion; means for identifying at least one mitochondrial heteroplasmy of interest; and means for using the DNA amplification and DNA sequencing systems to determine the presence or absence of the mitochondrial heteroplasmy within the eukaryotic cell from which the mitochondrion was obtained.
    Type: Grant
    Filed: May 4, 2011
    Date of Patent: December 22, 2015
    Assignee: Gettysburg College
    Inventors: Koren Holland Deckman, Barbara C. Levin, Kristian Helmerson, Rani B. Kishore, Joseph E. Reiner
  • ISOLATION AND CHARACTERIZATION OF A SINGLE MITOCHONDRION
    Publication number: 20110281269
    Abstract: A method for identifying mitochondrial heteroplasmy within eukaryotic cells is provided. This method includes means for isolating and capturing a single mitochondrion from at least one eukaryotic cell, wherein the means for isolating and capturing a single mitochondrion further includes optical tweezers or a similar optical technology; means for analyzing the isolated and captured mitochondrion, wherein the means for analyzing the isolated and captured mitochondrion further includes a DNA amplification system and a sequencing system for amplifying and sequencing DNA extracted from the mitochondrion; means for identifying at least one mitochondrial heteroplasmy of interest; and means for using the DNA amplification and DNA sequencing systems to determine the presence or absence of the mitochondrial heteroplasmy within the eukaryotic cell from which the mitochondrion was obtained.
    Type: Application
    Filed: May 4, 2011
    Publication date: November 17, 2011
    Applicant: GETTYSBURG COLLEGE
    Inventors: Koren Holland Deckman, Barbara C. Levin, Kristian Helmerson, Rani B. Kishore, Joseph E. Reiner
  • ISOLATION AND CHARACTERIZATION OF A SINGLE MITOCHONDRION
    Publication number: 20080254530
    Abstract: A system for identifying mitochondrial heteroplasmy within eukaryotic cells is provided. This system includes means for isolating and capturing a single mitochondrion from at least one eukaryotic cell, wherein the means for isolating and capturing a single mitochondrion further includes optical tweezers or a similar optical technology; means for analyzing the isolated and captured mitochondrion, wherein the means for analyzing the isolated and captured mitochondrion further includes a DNA amplification system and a sequencing system for amplifying and sequencing DNA extracted from the mitochondrion; means for identifying at least one mitochondrial heteroplasmy of interest; and means for using the DNA amplification and DNA sequencing systems to determine the presence or absence of the mitochondrial heteroplasmy within the eukaryotic cell from which the mitochondrion was obtained.
    Type: Application
    Filed: February 27, 2008
    Publication date: October 16, 2008
    Applicant: GETTYSBURG COLLEGE
    Inventors: Koren Holland Deckman, Barbara C. Levin, Kristian Helmerson, Rani B. Kishore, Joseph E. Reiner