Abstract: A gas delivery system and method are provided that include a therapeutic gas delivery device, and a high-frequency ventilator delivering a breathing gas to a respiratory circuit. The therapeutic gas delivery system also includes a flow sensor assembly having a single interior chamber. The flow sensor assembly includes a flow sensor connected with the therapeutic gas delivery device and configured to measure a flow rate of the breathing gas. The flow sensor has a sensor gas inlet and a sensor gas outlet. The flow sensor assembly further includes a one-way flow valve disposed downstream of the sensor gas outlet. The one-way flow valve includes a valve gas inlet and a valve gas outlet. Inner diameters of the valve gas inlet and the valve gas outlet are greater than or equal to an inner diameter of at least one of the sensor gas inlet and the sensor gas outlet.

Abstract: A valve integrated pressure regulator (VIPR) assembly for dispensing a gas from a compressed gas cylinder is provided. The valve integrated pressure regulator (VIPR) includes a continuously adjustable, low pressure flow meter valve and a flow sensor incorporated directly into the valve body of the VIPR assembly.

Abstract: A pressurized containment vessel for a gas/liquid mixture of nitric oxide in deionized and/or deoxygenated water and a system for dispensing the gas/liquid mixture of nitric oxide in deionized and/or deoxygenated water from the containment vessel are provided. The containment vessel and dispensing system are configured so as to maintain the gas/liquid mixture within the containment vessel at a constant pressure above ambient pressure as the gas/liquid mixture of nitric oxide in deionized and/or deoxygenated water is stored in and depleted from the containment vessel thus preventing the nitric oxide from coming out of the solution.

Abstract: A system and method for dispensing a nitric oxide solution, and more preferably a gas/liquid mixture of nitric oxide in a solvent, from a cylinder or other containment vessel are provided. The dispensing system and method are configured so as to maintain the nitric oxide based solution within the cylinder or containment vessel at a constant pressure above ambient pressure as the gas/liquid mixture is stored in and depleted from the containment vessel thus preventing the nitric oxide from coming out of the solution. In addition, a method of producing the gas/liquid mixture of nitric oxide in a solvent, such as deoxygenated and deionized water, as well as a cylinder filling method and apparatus are also provided.