Patents by Inventor Kosala RAJAPAKSHA

Kosala RAJAPAKSHA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROTEIN-FREE SEMEN CRYOPRESERVATION
    Publication number: 20240237634
    Abstract: This disclosure provides a preserving composition comprising a cholesterol:carrier complex, optionally a cholesterol:cyclodextrin complex (CC complex) and/or a cell permeable antioxidant peptide and a biological buffer and optionally a cryprotectant, wherein the preserving composition is optionally substantially free of animal phospholipid, animal protein and/or animal lipoprotein. The disclosure also provides methods for the use of the preserving composition in cryopreservation of semen or sperm cells. Also provided is a kit comprising the preserving composition having a CC complex, a biological buffer, a cryoprotectant, a carbohydrate, a pH stabilizer, an antibiotic or antibiotic cocktail and/or a cell permeable anti-oxidant peptide.
    Type: Application
    Filed: November 17, 2023
    Publication date: July 18, 2024
    Inventors: Francois Eudes, Jaswant Singh, Kosala Rajapaksha, Muhammad Anzar, Gregg P. Adams
  • Protein-free semen cryopreservation
    Patent number: 11819019
    Abstract: This disclosure provides a preserving composition comprising a cholesterol: carrier complex, optionally a cholesterol:cyclodextrin complex (CC complex) and/or a cell permeable antioxidant peptide and a biological buffer and optionally a cryprotectant, wherein the preserving composition is optionally substantially free of animal phospholipid, animal protein and/or animal lipoprotein. The disclosure also provides methods for the use of the preserving composition in cryopreservation of semen or sperm cells. Also provided is a kit comprising the preserving composition having a CC complex, a biological buffer, a cryoprotectant, a carbohydrate, a pH stabilizer, an antibiotic or antibiotic cocktail and/or a cell permeable anti-oxidant peptide.
    Type: Grant
    Filed: December 3, 2018
    Date of Patent: November 21, 2023
    Assignee: University of Saskatchewan
    Inventors: Francois Eudes, Jaswant Singh, Kosala Rajapaksha, Muhammad Anzar, Gregg P. Adams
  • PROTEIN-FREE SEMEN CRYOPRESERVATION
    Publication number: 20210059241
    Abstract: This disclosure provides a preserving composition comprising a cholesterol: carrier complex, optionally a cholesterol: cyclodextrin complex (CC complex) and/or a cell permeable antioxidant peptide and a biological buffer and optionally a cryprotectant, wherein the preserving composition is optionally substantially free of animal phospholipid, animal protein and/or animal lipoprotein. The disclosure also provides methods for the use of the preserving composition in cryopreservation of semen or sperm cells. Also provided is a kit comprising the preserving composition having a CC complex, a biological buffer, a cryoprotectant, a carbohydrate, a pH stabilizer, an antibiotic or antibiotic cocktail and/or a cell permeable anti-oxidant peptide.
    Type: Application
    Filed: December 3, 2018
    Publication date: March 4, 2021
    Inventors: Francois EUDES, Jaswant SINGH, Kosala RAJAPAKSHA, Muhammad ANZAR, Gregg P. ADAMS