Abstract: The present invention provides an automated analysis device capable of detecting whether or not a plurality of fluid control valves included in the automated analysis device operate normally at low cost. The automated analysis device according to the present invention includes a plurality of fluid control valves placed in a flow path, a pressure sensor (112) which measures pressure in the flow path, a liquid level detection element (103c) which detects a position of a liquid level of a liquid discharged by a discharge nozzle (120, 124), and a control unit (100). One or more of the fluid control valves act as a first fluid control valve (108, 110) connected to the pressure sensor (112) through the flow path. One or more of the fluid control valves act as a second fluid control valve (115, 118, 123) connected to the discharge nozzle (120, 124) through the flow path.

Abstract: An automatic analyzer 101 includes a judgment part 118f which descends a probe 201 in the direction of a reagent 205 and suspends the downward movement of the probe 201 at a first position PT higher than a liquid level value P0 assumed to be a height of a liquid level by a first predetermined value Db. The judgment part 118f determines that the reagent 205 is in a normal state when the liquid level is not detected by an electrostatic capacity sensor 206 at the first position PT. Further, the judgment part 118f determines that the reagent 205 in an abnormal state when the liquid level is detected by the electrostatic capacity sensor 206 before reaching the first position PT. An automatic analyzer capable of reducing consumption of consumables produced at the time of reagent registration compared with conventional cases is provided.

Abstract: Provided are an automatic analyzer that can decrease waiting time for a user and reduce running costs as compared with in the past and an operation method for the automatic analyzer. The analyzer includes: a first mechanism group that is used only in analysis for biochemical items; a second mechanism group that is used only in analysis for immunological items; a common mechanism group that is used in analysis for both biochemical items and immunological items; and a control part that activates the second mechanism group and common mechanism group without activating the first mechanism group when analysis for biochemical items is not required, and activates the first mechanism group and common mechanism group without activating the second mechanism group when analysis for immunological items is not required.

Abstract: The present disclosure provides a method for detecting a biomolecule. The method includes providing an electrode 101 and an aptamer 102 that specifically binds to a target biomolecule and has a charge, the aptamer 102 being disposed near the electrode 101; introducing a cationic mediator 113 having a charge opposite to the charge of the aptamer 102 to the electrode 101 at which the aptamer 102 is disposed; bringing a solution containing the target biomolecule into contact with the aptamer 102 to cause the aptamer 102 to bind to the biomolecule; and measuring an electrical signal that is produced at the electrode 101 in association with the cationic mediator 113.

Abstract: The present disclosure provides a positive electrode which includes a positive electrode current collector and a positive electrode mixture layer, wherein the positive electrode mixture layer contains sulfur and/or a sulfur compound, a ceramic material that is oxidized and reduced in a potential range of 1.0V (vs. Li/Li+) to 3.0V (vs. Li/Li+), a binder, and a proportion of the sulfur and/or the sulfur compound in the positive electrode mixture layer is 40% by mass to 80% by mass.

Abstract: A developing device includes a developer carrier, first and second chambers, first and second communication portions, first and second conveyance screws, a pair of sealing members, and a drive transmission gear. The developer carrier carries developer containing toner and carrier for developing an electrostatic image formed on an image carrier. The second chamber is partitioned from the first chamber. The first conveyance screw conveys the developer in a first direction from the first communication portion toward the second communication portion. The second conveyance screw conveys the developer in a second direction from the second communication portion toward the first communication portion. The sealing member pair seals the first and second communication portions to store initial developer in the second chamber. The drive transmission gear includes a fitting portion to which a tool to input a driving force for rotating the second conveyance screw to the drive transmission gear is fitted.

Abstract: An automatic analyzer performs a dispensing operation with high throughput while reducing a risk of carry-over of a reagent that includes first and second dispensing operations. The second dispensing operation includes a first procedure of aspirating a sample accommodated by a dispensing nozzle, a second procedure of discharging the aspirated sample to a first reaction container, a third procedure in which a cleaning tank cleans an inner side and an outer side of the dispensing nozzle after the second procedure, a fourth procedure of aspirating the reagent accommodated in a reagent container after the third procedure, a fifth procedure B5 in which the cleaning tank cleans the outer side of the dispensing nozzle after the fourth procedure, a sixth procedure of aspirating the sample accommodated in the first reaction container after the fifth procedure, and a seventh procedure of discharging the reagent and the sample to a second reaction container.

Abstract: Provided is a technology that enables stirring of a liquid containing fine particles without providing a dedicated stirring mechanism. An automatic analyzer according to the present disclosure includes a probe that aspirates and discharges a specimen and a reagent, and a control unit that controls an operation of the probe, in which the control unit controls the probe so that the specimen, the reagent, and fine particles are dispensed to an empty vessel to obtain a liquid mixture, and a first stirring of aspirating, discharging, and stirring the liquid mixture in the vessel before precipitation of the fine particles after the dispensing, and a second stirring of aspirating, discharging, and stirring the liquid mixture in the vessel after the precipitation of the fine particles after the first stirring are performed.

Abstract: The purpose of the present invention is to provide an automatic analysis device capable of ensuring accuracy in a wide range of a pipetting amount without changing the rotation/vertical speed of a sampling arm and the aspiration speed of a pump. The automatic analysis device according to the present invention, which is an automatic analysis device for analyzing a target substance included in a sample, is characterized by comprising: a detection unit that analyzes the sample; and a probe that pipettes a liquid, wherein the probe changes the number of aspiration by which the liquid is aspirated into the probe according to the pipetting amount by which the probe pipettes the liquid.

Abstract: The object of the invention is to provide an automatic analysis apparatus capable of setting a dispensing mechanism for measuring dispensing accuracy and a dispensing volume, and capable of performing dispensing accuracy measurement without absorbance measurement. Regarding a dispensing accuracy, a dispensing mechanism to be measured is designated. Parameters including a dispensing volume and the like are input. A dispensing operation of the input dispensing volume is automatically performed for each designated dispensing mechanism. A reaction vessel contains, for example, a reagent of the input dispensing volume which has been dispensed by the designated dispensing mechanism. By measuring a weight of the reagent in the reaction vessel, or the like, it is possible to measure the dispensing accuracy of the designated dispensing mechanism.

Abstract: An abnormality is detected with high accuracy at the time of pipetting a liquid to be subjected to abnormality detection.

Abstract: A first learning unit (101) learns a difference model (111) for predicting a difference between current monitoring data that is monitoring data obtained by monitoring a monitoring target at each time point and at each of a plurality of monitoring points and is monitoring data at a current time point, and past monitoring data that is monitoring data at each of a plurality of past time points; a second learning unit (102) learns a prediction model (past) (112) for predicting variation of the monitoring target using the past monitoring data; a first generation unit (103) generates corrected past data using the difference model (111), by correcting a difference between the past monitoring data and the current monitoring data; and a third learning unit (104) learns a prediction model (current) (113) for predicting variation of the monitoring target using the current monitoring data, the difference model (111), the prediction model (past) (112), and the corrected past data, whereby variation of the monitoring targe

Abstract: [Task] To provide an automatic analysis apparatus including a photomultiplier tube which controls a sensitivity of the photomultiplier tube without adjusting a high voltage value. [Solution] An automatic analysis apparatus according to the present invention includes a photomultiplier tube which detects light from a reaction vessel; a determination unit which determines an output signal of the photomultiplier tube in a case where the photomultiplier tube is irradiated with first light; and a control unit which irradiates the photomultiplier tube with second light to lower a sensitivity of the photomultiplier tube in accordance with a determination result by the determination unit.

Abstract: The present invention can perform a human flow simulation in real time. An input unit (102) receives an input of passage information indicating passage through a point, a measurement unit (103) measures the number of passing people through the point by adding the received passage information, and a transmission unit (104) transmits the number of passing people measured by the measurement unit (103) at a predetermined time interval to a server that generates a parameter of a human flow simulation.

Abstract: A vector field setting unit (102) sets a vector field for providing virtual force for reproducing, in a region in which a moving body moves, movement of the moving body in a certain direction, and a simulation unit (104) simulates the movement of the moving body in the region, based on a movement model to which a parameter for simulating the movement of the moving body is set and the vector field set by the vector field setting unit, whereby the movement of the moving body is appropriately simulated even when the movement of the moving body is unusual.

Abstract: A path specific traffic volume estimation unit (130) estimates a path specific traffic volume corresponding to a traffic volume of observation objects at each time point at each of path candidates on the basis of observation value data that represents the number of the observation objects at each time point at each of a plurality of observation spots, observation spot specific reliability data that represents a reliability of the observation value data at each time point at each of the plurality of observation spots, and a path candidate list that represents a set of the path candidates through which the observation objects move.

Abstract: An estimation device (10) includes an input unit (30) and an estimation unit (32). A first observation value (40) for each of a plurality of observation areas (50), the first observation value being the number of presences (S) of persons who are observation targets at each of a plurality of observation times, and a second observation value (42) for each of a plurality of observation points (52) included in any one of the plurality of observation areas (50), the second observation value being the number of passages (C) of the persons at each of the plurality of observation times, are input to the input unit (30).

Abstract: An automatic analyzer includes a tube pump, a mounting unit that mounts the liquid delivery target container, a drive mechanism, a liquid surface detecting unit, and a control unit. The tube pump delivers the liquid to the liquid delivery target container during design liquid delivery time necessary to deliver the liquid in a design liquid delivery amount before the tube pump is degraded. The drive mechanism moves the mounting unit mounting the liquid delivery target container from a first position to a second position at which the liquid surface is to be detected by the liquid surface detecting unit. The control unit computes an actual liquid delivery amount of the liquid for the design liquid delivery time based on the first and the second positions, and the control unit determines a degradation state of the tube pump based on the design liquid delivery amount and the actual liquid delivery amount.

Abstract: An estimation device (10) includes an input unit (30) and an estimation unit (32). A first observation value (40) for each of a plurality of observation areas (50), the first observation value being the number of presences (S) of persons who are observation targets at each of a plurality of observation times, and a second observation value (42) for each of a plurality of observation points (52) included in any one of the plurality of observation areas (50), the second observation value being the number of passages (C) of the persons at each of the plurality of observation times, are input to the input unit (30). The estimation unit (32) optimizes an objective function based on the objective function in a simulation Sim, a constraint condition (G) satisfied between the first observation value (40) and the second observation value (42), the first observation value (40), and the second observation value (42) to estimate a parameter (Param_sim).