Patents by Inventor Kosrat Amin
Kosrat Amin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Novel 3-Bicyclocarbonylaminopyridine-2-Carboxamides or 3-Bicyclocarbonylaminopyrazine-2-Carboxamides
Publication number: 20090181968Abstract: The present invention relates to compounds of formula (I) [Chemical formula should be inserted here. Please see paper copy] as well as pharmaceutically acceptable salts and pharmaceutical compositions including the compounds are prepared or thereof: wherein, A1, A2, R1, R2, R3, R4, and R5 and n are as defined in the specification. The compounds of formula (I) are useful in therapy.Type: ApplicationFiled: November 22, 2006Publication date: July 16, 2009Applicant: ASTRAZENECA ABInventors: Kosrat Amin, Johan Broddefalk, Yantao Chen, Karolina Nilsson, Claire Milburn, Helene Desfosses, Ziping Liu, Maxime Tremblay, Christopher Walpole, Zhong-yong Wei, Hua Yang -
Publication number: 20090018166Abstract: The present invention relates to certain new pyridin analogues of Formula (I) to processes for preparing such compounds, to their utility as P2Y12 inhibitors and as anti-trombotic agents etc, their use as medicaments in cardiovascular diseases as well as pharmaceutical compositions containing them.Type: ApplicationFiled: January 11, 2008Publication date: January 15, 2009Applicant: ASTRAZENECA ABInventors: Kosrat Amin, Thomas Antonsson, Christoffer Bengtsson, David Brown, Ruth Bylund, Daniel Hovdal, Fabrizio Giordanetto, Johan Johansson
-
Publication number: 20080214495Abstract: The invention relates to compounds of formula (I), wherein R1 and R3 are independently selected from carbon and nitrogen; R2 is oxo or thioxo; n is 0, 1 or 2; each R10 is independently selected from hydrogen and C1-3alkyl; R4 and R5 are each selected from carbon and nitrogen, wherein at least one of R4 and R5 is nitrogen; R6 is hydrogen or oxo; R7 is an aliphatic, partially saturated or aromatic carbocyclic ring, said carbocyclic ring having 0, 1 or 2 hetero nitrogen; m is 0, 1 or 2; each R11 is independently selected from hydrogen, hydroxy, oxo, C1-5alkyl, carboxy, hydroxyC1-5alkyl, carboxyC1-5alkyl, C1-5alkoxy-oxoC1-5alkyl, carbamoyl, C1-5alkylcarbamoyl, di (C1-5 alkyl)carbamoyl, carbamoylC1-4alkyl,C1-5alkylcarbamoylC1-4alkyl, di(C1-5alkyl)carbamoylC1-4alkyl, hydroxyC1-5alkylcarbamoyl, C1-5 alkoxyC1-5alkylcarbamoyl, hydroxyC1-5alkylcarbamoylC1-4alkyl, C1-5alkoxyC1-5 alkylcarbamoylC1-4 alkyl, CONR80(CH2)xS(O)pR90, CONH(CH2)qNR100R100, —C1-5 alkyl-Y1, —COOCHR170R180 and —CON R170R180; R8 is a bond, C1-4alkyleType: ApplicationFiled: July 5, 2006Publication date: September 4, 2008Applicant: ASTRAZENECA ABInventors: Christer Alstermark, Kosrat Amin, Kjell Andersson, Yantao Chen, Ulf Fahlander, Kevin Michael Foote, Kenneth Granberg, Daniel Hovdal
-
Publication number: 20080200431Abstract: The invention relates to compounds of formula (I), Chemical formula should be inserted here.Type: ApplicationFiled: July 5, 2006Publication date: August 21, 2008Applicant: ASTRAZENECA ABInventors: Christer Alstermark, Kosrat Amin, Kjell Andersson, Ulf Fahlander, Kenneth Granberg, Daniel Hovdal
-
Publication number: 20070225292Abstract: Compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4, n and A are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.Type: ApplicationFiled: May 20, 2005Publication date: September 27, 2007Inventors: Kosrat Amin, Johan Broddefalk, Helene Desfosses, Emma Evertsson, Ziping Liu, Claire Milburn, Karolina Nilsson, Maxime Tremblay, Christopher Walpole, Zhong-yong Wei, Hua Yang
-
Publication number: 20050154007Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: ApplicationFiled: June 30, 2004Publication date: July 14, 2005Inventors: Kosrat Amin, Mikael Dahlstrom, Peter Nordberg, Ingemar Starke
-
Publication number: 20040220209Abstract: The present invention relates to imidazo pyridine derivatives of the formula (I) whichinhibit exogenously or endogenously stimulated gastric acid secretion and thus can be usedin the prevention and treatment of gastrointestinal inflammatory diseases.Type: ApplicationFiled: February 19, 2004Publication date: November 4, 2004Inventors: Kosrat Amin, Mikael Dahlstrom, Peter Nordberg, Ingemar Starke
-
Patent number: 6790960Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: May 5, 2003Date of Patent: September 14, 2004Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Publication number: 20030220364Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: ApplicationFiled: May 5, 2003Publication date: November 27, 2003Inventors: Kosrat Amin, Mikael Dahlstrom, Peter Nordberg, Ingemar Starke
-
Patent number: 6613775Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: October 22, 1999Date of Patent: September 2, 2003Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6596711Abstract: Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)methylphosphinic acid; ii) (S)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iii) (R)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iv) (3-amino-2-hydroxypropyl)difluoromethylphosphinic acid; and v) (3-amino-2-oxopropyl)methylphosphinic acid, having affinity to one or more GABAB receptors, their pharmaceutically acceptable salts, solvates and stereoisomers, as well as a process for their preparation, pharmaceutical compositions containing said therapeutically active compounds and the use of said active compounds in therapy.Type: GrantFiled: March 1, 2001Date of Patent: July 22, 2003Assignee: AstraZeneca ABInventors: Kosrat Amin, Thomas Elebring, Peter Guzzo, Thomas Olsson, Marianne Swanson, Sverker Von Unge
-
Patent number: 6579884Abstract: The present invention relates to novel compounds, and therapeutically acceptable salts thereof of the formula (I), which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: October 13, 1999Date of Patent: June 17, 2003Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6518270Abstract: The present invention relates to heterocyclic compounds of the formula (I), in which the phenyl moiety is substituted with lower alkyl in 2- and 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: February 8, 2000Date of Patent: February 11, 2003Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6465505Abstract: The present invention relates to benzimidazole derivatives of the formula (I), in which the phenyl moiety is substituted with lower alkyl in 2- and 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: July 17, 1997Date of Patent: October 15, 2002Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6313136Abstract: The present invention relates to imidazo pyridine derivatives of the formula (I), in which the phenyl moiety is substituted, and in which the imidazo pyridine moiety is substituted with a carboxamide group in 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: June 14, 1999Date of Patent: November 6, 2001Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6313137Abstract: The present invention relates to imidazo pyridine derivatives of the formula (I), in which the phenyl moiety is substituted, and in which the imidazo pyridine moiety is substituted with a carboxamide group in 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: June 14, 1999Date of Patent: November 6, 2001Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke
-
Patent number: 6265415Abstract: The present invention relates to imidazo pyridine derivatives of the formula (I), in which the phenyl moiety is substituted with lower alkyl in 2- and 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.Type: GrantFiled: March 10, 1998Date of Patent: July 24, 2001Assignee: AstraZeneca ABInventors: Kosrat Amin, Mikael Dahlström, Peter Nordberg, Ingemar Starke