Patents by Inventor Kostadin Apostolov

Kostadin Apostolov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cell lines
    Patent number: 3935066
    Abstract: A human epithelial heterploid liver cell line, such as line WRL 68 which forms individually separated islands or discrete clumps when cultured in a growth medium, has a morphology closely resembling that of hepatocytes of the human liver and a generation time not more than 24 hours, manifests increased production of glycogen in the presence of 1% glucose in the medium, and is capable of supporting viruses.Such cells may be advantageously used to provide cell cultures for supporting viruses for the preparation of viral vaccines.
    Type: Grant
    Filed: December 13, 1974
    Date of Patent: January 27, 1976
    Assignee: Burroughs Wellcome Co.
    Inventor: Kostadin Apostolov