Patents by Inventor Kostas Kostarelos

Kostas Kostarelos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NANOPARTICLE-ENABLED ANALYSIS OF CELL-FREE NUCLEIC ACID IN COMPLEX BIOLOGICAL FLUIDS
    Publication number: 20230417741
    Abstract: The invention relates to methods for capturing, quantifying and analyzing cell free nucleic acid (cfNA) in biofluid samples, such as blood and urine.
    Type: Application
    Filed: August 9, 2021
    Publication date: December 28, 2023
    Inventors: Marilena HADJIDEMETRIOU, Kostas KOSTARELOS, Lois GARDNER
  • MULTIOMIC ANALYSIS OF NANOPARTICLE-CORONAS
    Publication number: 20230266328
    Abstract: The present invention relates to methods for simultaneously identifying and/or detecting distinct classes of biomarker in biofluid samples, such as blood.
    Type: Application
    Filed: August 9, 2021
    Publication date: August 24, 2023
    Inventors: Marilena HADJIDEMETRIOU, Kostas KOSTARELOS, Lois GARDNER, Lana PAPAFILIPPOU
  • Detection of cancer biomarkers using nanoparticles
    Patent number: 11598779
    Abstract: Methods for identifying and detecting potential disease specific biomarkers from biofluids. The methods involve in vivo administration of nanoparticles to a subject in a diseased state or incubating nanoparticles in a biofluid sample taken from a subject in a diseased state and analysis of the biomolecule corona formed on said nanoparticles. The methods distinguish between a healthy and diseased state in a subject, such as, for example, the presence of a tumor in a human subject.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: March 7, 2023
    Assignee: THE UNIVERSITY OF MANCHESTER
    Inventors: Kostas Kostarelos, Marilena Hadjidemetriou
  • DETECTION OF CANCER BIOMARKERS USING NANOPARTICLES
    Publication number: 20210132071
    Abstract: Methods for identifying and detecting potential disease specific biomarkers from biofluids. The methods involve in vivo administration of nanoparticles to a subject in a diseased state or incubating nanoparticles in a biofluid sample taken from a subject in a diseased state and analysis of the biomolecule corona formed on said nanoparticles. The methods distinguish between a healthy and diseased state in a subject, such as, for example, the presence of a tumor in a human subject.
    Type: Application
    Filed: September 6, 2017
    Publication date: May 6, 2021
    Inventor: Kostas Kostarelos
  • Non-covalent complexes comprising carbon nanotubes
    Patent number: 7858648
    Abstract: The present invention relates to the use of a carbon nanotube comprising positive and/or negative charges, the charges being carried by at least one charge-carrying group, the charge carrying group being covalently bound to the surface of the carbon nanotube, for the manufacture of a complex between the carbon nanotube and at least one charged molecule, the bond between the carbon nanotube and the charged molecule being essentially electrostatic, and the charged molecule comprising at least one negative charge if the carbon nanotube comprises positive charges and/or at least one positive charge if the carbon nanotube comprises negative charges.
    Type: Grant
    Filed: June 6, 2005
    Date of Patent: December 28, 2010
    Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), University of London, The School of Pharmacy, Universita degli Studi di Trieste
    Inventors: Alberto Bianco, Davide Pantarotto, Kostas Kostarelos, Maurizio Prato
  • Non-Covalent Complexes Comprising Carbon Nanotubes
    Publication number: 20080076816
    Abstract: The present invention relates to the use of a carbon nanotube comprising positive and/or negative charges, the charges being carried by at least one charge-carrying group, the charge carrying group being covalently bound to the surface of the carbon nanotube, for the manufacture of a complex between the carbon nanotube and at least one charged molecule, the bond between the carbon nanotube and the charged molecule being essentially electrostatic, and the charged molecule comprising at least one negative charge if the carbon nanotube comprises positive charges and/or at least one positive charge if the carbon nanotube comprises negative charges.
    Type: Application
    Filed: June 6, 2005
    Publication date: March 27, 2008
    Inventors: Alberto Bianco, Davide Pantarotto, Kostas Kostarelos, Maurizio Prato