Patents by Inventor Kostas Saranteas

Kostas Saranteas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALTS, CRYSTAL FORMS, AND PRODUCTION METHODS THEREOF
    Publication number: 20220402937
    Abstract: Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.
    Type: Application
    Filed: July 22, 2022
    Publication date: December 22, 2022
    Applicant: Sunovion Pharmaceuticals Inc.
    Inventors: Andrea BAUER, Nandkumar Nivritti BHOGLE, Xiaoxia CHEN, Shahla JAMZAD, Robert Joseph PRYTKO, Kostas SARANTEAS, Michael Joseph SIZENSKY, Harold Scott WILKINSON, Haitao ZHANG
  • Salts, crystal forms, and production methods thereof
    Patent number: 11440921
    Abstract: Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: September 13, 2022
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Andrea Bauer, Nandkumar Nivritti Bhogle, Xiaoxia Chen, Shahla Jamzad, Robert Joseph Prytko, Kostas Saranteas, Michael Joseph Sizensky, Harold Scott Wilkinson, Haitao Zhang
  • SALTS, CRYSTAL FORMS, AND PRODUCTION METHODS THEREOF
    Publication number: 20210053983
    Abstract: Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.
    Type: Application
    Filed: August 28, 2020
    Publication date: February 25, 2021
    Applicant: Sunovion Pharmaceuticals Inc.
    Inventors: Andrea BAUER, Nandkumar Nivritti BHOGLE, Xiaoxia CHEN, Shahla JAMZAD, Robert Joseph PRYTKO, Kostas SARANTEAS, Michael Joseph SIZENSKY, Harold Scott WILKINSON, Haitao ZHANG
  • SALTS OF A HETEROCYCLIC COMPOUND AND CRYSTALLINE FORMS, PROCESSES FOR PREPARING, THERAPEUTIC USES, AND PHARMACEUTICAL COMPOSITIONS THEREOF
    Publication number: 20190375764
    Abstract: The present disclosure relates to salts of (R)-1-(3,4-dihydro-1H-[1,4]oxazino[4,3-b]indazol-1-yl)-N-methylmethanamine, crystalline forms thereof, and methods of preparation thereof, which are useful in the treatment of CNS disorders.
    Type: Application
    Filed: June 6, 2019
    Publication date: December 12, 2019
    Inventors: Nandkumar Nivritti BHOGLE, Yuji FUJIWARA, Kenjiro HIRA, Tomoya KARASAWA, Kostas SARANTEAS, John R. SNOONIAN, Harold Scott WILKINSON, Haitao ZHANG
  • SALTS, CRYSTAL FORMS, AND PRODUCTION METHODS THEREOF
    Publication number: 20190256525
    Abstract: Provided are salts of (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine and various of crystal forms thereof, and compositions, medicaments, pharmaceutically acceptable formulations thereof, and methods of making same. In addition, provided are compounds comprising specific particle size distributions of crystalline (S)-(4,5-dihydro-7H-thieno[2,3-c]pyran-7-yl)-N-methylmethanamine HCl and methods of making and modulating the particle size distributions.
    Type: Application
    Filed: February 15, 2019
    Publication date: August 22, 2019
    Inventors: Andrea Bauer, Nandkumar Nivritti Bhogle, Xiaoxia Chen, Shahla Jamzad, Robert Joseph Prytko, Kostas Saranteas, Harold Scott Wilkinson, Haitao Zhang
  • MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE
    Publication number: 20150203501
    Abstract: A novel maleate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: October 28, 2014
    Publication date: July 23, 2015
    Inventors: H. Scott WILKINSON, Richard HSIA, Tushar MISRA, Kostas SARANTEAS, Patrick MOUSAW
  • Method for treating a sleep disorder with eszopiclone maleate
    Patent number: 8889685
    Abstract: Maleate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided. The salts are useful for treating sleep disorders.
    Type: Grant
    Filed: June 27, 2013
    Date of Patent: November 18, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • Method of decreasing the bitterness of a pharmaceutical dosage form containing zopiclone
    Patent number: 8889686
    Abstract: L malate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are disclosed for decreasing the bitterness of eszopiclone dosage forms
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: November 18, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • Method for treating anxiety with a dosage form of besylate salts of zopiclone or eszopiclone
    Patent number: 8809332
    Abstract: Besylate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: August 19, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Richard Hsia, H. Scott Wilkinson, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • L-MALATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRAZINE
    Publication number: 20130296565
    Abstract: A novel L-malate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: July 1, 2013
    Publication date: November 7, 2013
    Inventors: H. Scott WILKINSON, Richard HSIA, Tushar MISRA, Kostas SARANTEAS, Patrick MOUSAW
  • Besylate Salts of 6-(5-Chloro-2-Pyridyl)-5-[(4-Methyl-1-Piperazinyl)Carbonyloxy]-7-oxo-6,7-dihydro-5H-Pyrrolo[3,4-b]Pyrazine
    Publication number: 20130289039
    Abstract: A novel besylate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: June 26, 2013
    Publication date: October 31, 2013
    Inventors: Richard Hsia, H. Scott WILKINSON, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE
    Publication number: 20130289040
    Abstract: A novel maleate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: June 27, 2013
    Publication date: October 31, 2013
    Inventors: H. Scott WILKINSON, Richard HSIA, Tushar MISRA, Kostas Saranteas, Patrick MOUSAW
  • Method for treating a sleep disorder with a dosage form of a zopiclone or eszopiclone L-malate salt
    Patent number: 8541416
    Abstract: L-malate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl) carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: September 24, 2013
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • Method for providing blood levels of eszopiclone with maleate salts
    Patent number: 8497268
    Abstract: Maleate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided. The salts are useful to provide blood levels of eszopiclone that are independent of fasting state.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: July 30, 2013
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • Method for treating a sleep disorder with a dosage form of besylate salts of zopiclone or eszopiclone
    Patent number: 8497267
    Abstract: Besylate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: July 30, 2013
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Richard Hsia, H. Scott Wilkinson, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • MALEATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-b]PYRAZINE
    Publication number: 20120238580
    Abstract: A novel maleate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: May 30, 2012
    Publication date: September 20, 2012
    Applicant: SUNOVION PHARMACEUTICALS INC.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • L-malate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-Oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
    Patent number: 8269005
    Abstract: L-malate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) are provided.
    Type: Grant
    Filed: July 7, 2009
    Date of Patent: September 18, 2012
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas
  • Maleate salts of 6-(5-chloro-2-Pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine
    Patent number: 8268832
    Abstract: Pharmaceutical compositions of maleate salts of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo [3,4-b]pyrazine) are provided. The maleate salts are sleep agents useful in oral dosage forms.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: September 18, 2012
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: H. Scott Wilkinson, Richard Hsia, Tushar Misra, Kostas Saranteas, Patrick Mousaw
  • L-MALATE SALTS OF 6-(5-CHLORO-2-PYRIDYL)-5-[(4-METHYL-1-PIPERAZINYL)CARBONYLOXY]-7-OXO-6,7-DIHYDRO-5H-PYRROLO[3,4-B]PYRAZINE
    Publication number: 20120220597
    Abstract: A novel L-malate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: May 11, 2012
    Publication date: August 30, 2012
    Applicant: SUNOVION PHARMACEUTICALS INC.
    Inventors: H. Scott WILKINSON, Richard HSIA, Tushar MISRA, Kostas SARANTEAS, Patrick MOUSAW
  • Besylate Salts of 6-(5-Chloro-2-Pyridyl)-5-[(4 Methyl-1-Piperazinyl)Carbonyloxy]-7-oxo-6, 7-dihydro-5H-Pyrrolo[3,4-b]Pyrazine
    Publication number: 20120220598
    Abstract: A novel besylate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.
    Type: Application
    Filed: May 11, 2012
    Publication date: August 30, 2012
    Applicant: SUNOVION PHARMACEUTICALS INC.
    Inventors: Richard HSIA, H. Scott Wilkinson, Tushar Misra, Kostas Saranteas, Patrick Mousaw