Patents by Inventor Kosuke MANO

Kosuke MANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230348669
    Abstract: Provided is a compound represented by General Formula (1) in General Formula (1), Ar1 and Ar2 independently represent a group selected from the following Formulae,
    Type: Application
    Filed: July 5, 2023
    Publication date: November 2, 2023
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Shintaro MAEKAWA, Yoshiyuki TOTANI, Kosuke MANO
  • Patent number: 11746187
    Abstract: Provided is a compound represented by General Formula (1) in General Formula (1), Ar1 and Ar2 independently represent a group selected from the following Formulae,
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: September 5, 2023
    Assignee: MITSUI CHEMICALS, INC.
    Inventors: Shintaro Maekawa, Yoshiyuki Totani, Kosuke Mano
  • Publication number: 20230022186
    Abstract: Provided is a compound represented by General Formula (1) in General Formula (1), Ar1 and Ar2 independently represent a group selected from the following Formulae,
    Type: Application
    Filed: July 27, 2021
    Publication date: January 26, 2023
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Shintaro MAEKAWA, Yoshiyuki TOTANI, Kosuke MANO
  • Patent number: 11442066
    Abstract: Finding a protein of a minute amount present on a cell membrane to provide a method for producing an antibody against the protein. Producing an antibody using a protein identified by an identification method including: a labeling step of using a labeling agent comprising at least one selected from bis-iminobiotin compounds and bis-biotin compounds to obtain cells having a labeled protein; a degradation step of preparing a degradation product for an immobilization treatment, the degradation product containing the labeled protein; an immobilization step of immobilizing the labeled protein contained in the degradation product for an immobilization treatment on a stationary phase via a streptavidin mutant; a cleavage step of releasing an analysis sample from the stationary phase on which the labeled protein is immobilized; and an analysis step of analyzing the analysis sample to identify the labeled protein.
    Type: Grant
    Filed: February 19, 2018
    Date of Patent: September 13, 2022
    Assignees: MITSUI CHEMICALS, INC, NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION HEALTH AND NUTRITION, SAVID THERAPEUTICS INC.
    Inventors: Tsuneji Suzuki, Yoshiyuki Totani, Kosuke Mano, Shinichi Banba, Haruhiko Kamada, Taisuke Nakayama, Hiroki Akiba, Kouhei Tsumoto, Tsuyoshi Inoue
  • Publication number: 20210030882
    Abstract: A bis-iminobiotin compound which has a structure that enables the easy bonding of a bis-iminobiotin moiety to a drug or a fluorescent compound and is useful for the delivery of a drug to a streptavidin-labeled substance. The bis-iminobiotin compound is represented by general formula 9. In the formula, A, D and E independently represent a spacer capable of bonding two bicyclo rings to each other, wherein E represents a structure that may be branched, each of A, D and E may have a substituent, and A, D and E may together form a cyclic structure; J represents a functional group for achieving a click reaction; G represents a spacer capable of bonding E to J; and R represents a hydrogen atom, an acetyl group, a benzyl group, a trifluoroacetyl group or a Boc group.
    Type: Application
    Filed: March 29, 2019
    Publication date: February 4, 2021
    Applicants: Mitsui Chemicals, Inc., The University of Tokyo, Savid Therapeutics Inc.
    Inventors: Tsuneji SUZUKI, Kosuke MANO, Yoshiyuki TOTANII, Yohei SHIMIZU, Akira SUGIYAMA, Masanobu TSUKAGOSHI
  • Publication number: 20190383821
    Abstract: Finding a protein of a minute amount present on a cell membrane to provide a method for producing an antibody against the protein. Producing an antibody using a protein identified by an identification method including: a labeling step of using a labeling agent comprising at least one selected from bis-iminobiotin compounds and bis-biotin compounds to obtain cells having a labeled protein; a degradation step of preparing a degradation product for an immobilization treatment, the degradation product containing the labeled protein; an immobilization step of immobilizing the labeled protein contained in the degradation product for an immobilization treatment on a stationary phase via a streptavidin mutant; a cleavage step of releasing an analysis sample from the stationary phase on which the labeled protein is immobilized; and an analysis step of analyzing the analysis sample to identify the labeled protein.
    Type: Application
    Filed: February 19, 2018
    Publication date: December 19, 2019
    Applicants: MITSUI CHEMICALS, INC., NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION, SAVID THERAPEUTICS INC.
    Inventors: Tsuneji SUZUKI, Yoshiyuki TOTANI, Kosuke MANO, Shinichi BANBA, Haruhiko KAMADA, Taisuke NAKAYAMA, Hiroki AKIBA, Kouhei TSUMOTO, Tsuyoshi INOUE