Abstract: An object of the present invention is to provide a biocompatible carrier material capable of locally releasing particles. The present inventors have found that by using a non-gelling polymer formed by reversibly bonding a plurality of hydrophilic polymer units as a carrier material, it is possible to locally release particles to an affected part such as an ulcer surface, thereby enhancing gene transduction specificity and reducing off-target effects.

Abstract: An object of the present invention is to provide a novel gel having a fibrous shape and being excellent in physical properties such as toughness and elastic modulus, and a fibrous polymer material for obtaining such a gel. A fibrous polymer material having anisotropic swellability in water, including: a network structure in which a crystalline polymer containing a polyvinyl alcohol skeleton in a main chain is crosslinked, wherein the fibrous polymer material simultaneously exhibits following a) to c) in an equilibrium swelling state in water, and simultaneously exhibits following d) and e) from a dry state (static crystal stabilized state) to an equilibrium swelling state in water.

Abstract: [Object] An object of the present invention is to provide a novel artificial slime-like polymer material capable of controlling flow characteristics without changing a chemical composition such as a main chain skeleton or a solvent constituting the polymer material. [Solution] It is found that a slime-like polymer material in which liquid-liquid phase separation is induced can be provided and fluidity of the polymer material can be controlled by adding a polymer that does not react with a polymer unit serving as a basic skeleton constituting the polymer material in addition to the polymer unit.

Abstract: An object is to provide a novel artificial slime-like polymer material having stability against an external solvent without changing the chemical composition of a main chain skeleton, a solvent, and the like constituting the polymer material and without impairing the viscosity and elasticity of the slime-like material. It has been found that by controlling the number of branches, terminal connectivity, and concentration of polymer units constituting the polymer material, it is possible to provide a slime-like polymer material that induces liquid-liquid phase separation and thereby control solubility in external solvents.

Abstract: An object of the present invention is to provide a method for producing a hydrogel material having a ?m-scale porous structure in a simple manner.

Abstract: To provide a method for suppressing the entry of scar tissue in the treatment of a tendon or ligament, promoting healing by intratendinous cells, and efficiently restoring the original function of the tendon. A gel material including a polymer gel for suppressing expression of type III collagen in the treatment of an injured or ruptured tendon or ligament, in which the polymer gel is a hydrogel having a three-dimensional network structure formed by crosslinking of hydrophilic polymers, and has a polymer content of from 1 to 5% by weight and an elastic modulus of from 100 to 10000 Pa.

Abstract: An object of the present invention is to provide a novel use in which a polymer gel material having a µm-scale porous structure can be suitably used. A gel material for regenerative medicine comprising a polymer gel in which hydrophilic polymer units are crosslinked with each other, wherein the polymer gel contains water as a solvent and has a three-dimensional network structure having two regions: a first region in which the polymer units are densely present and a second region in which the polymer units are sparsely present, and a mesh size composed of the first region is the range of 1 to 500 µm.

Abstract: An object of the present invention is to provide a hemostatic method, a vascular occlusion method, a tissue covering method, and a body fluid coagulation method that are safe and efficient using a polymer material that is a non-biologically derived synthetic product. A solution (pre-gel solution) is prepared that contains, under a specific concentration condition, a hydrophilic polymer capable of forming a hydrogel by intermolecular crosslinking and has a specific pH condition and specific ionic strength, and the solution is gelled in situ in an environment, such as a bleeding site or the interior of a blood vessel, where blood is present.

Abstract: A combination of an artificial flower-forming ribbon and a tack plate wherein the ribbon includes a pair of strips overlapped with respect to each other and at least one string disposed along and interposed between the strips, the string being joined to one end of each of the strips at one end thereof, while the strips are adhered to each other at at least two portions on each of a plurality of lines spaced apart in the longitudinal direction of the strips so as to permit relative movement between the strips and the string in order to form the flower petals. The tack plate includes a slit which extends from a central portion thereof to a peripheral edge portion thereof whereby insertion of the strips and/or string into and through the tack plate is simplified and facilitated. A central hole is also provided within the tack plate and in communication with the slit so as to accommodate the string once the same has been inserted within the tack plate.

Abstract: A combination of an artificial-flower-forming ribbon and a tack plate, wherein the artificial-flower-forming ribbon having a pair of strips overlapped with respect to each other and at least one string placed along and between the strips, the string being joined to one end of each of the strips at one end thereof, the strips being adhered to each other at least at two portions on each of a plurality of lines spaced apart in the longitudinal direction of the strips so as to permit relative movement of the strips and string placed between the strips. The tack plate includes a first plate member having at least one slit or hole, through which both of the strips and string are passed, and a second plate member having adhesive films on both surfaces thereof. The second plate member is joined at one surface thereof to the first plate member and one of the strips passed through the slit or hole of the first plate member.