Abstract: A culture device includes a composition ratio control mechanism that measures a composition ratio of a mixed gas in a space above a liquid surface of a culture solution in a culture tank and supplies an adjustment gas into the space in accordance with the measured composition ratio of the mixed gas to maintain the composition ratio of the mixed gas in the space at a target value outside a preset explosive range, and a dissolution rate control mechanism that measures, during the culture, a combustible gas dissolution rate, which is a proportion of a combustible gas dissolved in the culture solution, to the combustible gas contained in a raw material gas supplied to the culture tank through a gas circulation path or a raw material gas supply unit, and maintains the measured combustible gas dissolution rate at or above a preset target value.

Abstract: Provide are a cell culture method which includes using a culture vessel which contains a cell suspension containing cells and discharging a gas including 30% by volume or more of oxygen into the cell suspension from a sparger disposed in the culture vessel to culture the cells, in which an average hole diameter in a gas discharge portion in the sparger is 1 ?m or more and 300 ?m or less, and a surface area A (m2) in the gas discharge portion in the sparger, a volume X (m3) of the cell suspension in the culture vessel, and a flow rate Q (m3/min) of the gas that is discharged from the sparger satisfy a specific relationship, a product producing method including the cell culture method, and a cell culture device that enables the cell culture method.

Abstract: Provided is a method for manufacturing a product, including a culture step of culturing cells in a culture solution in a tank having a capacity of 100 L or more, and a separation step of using a hollow fiber membrane filter comprising a plurality of hollow fiber membrane, each having a primary flow passage extending in a longitudinal direction, and a housing having a secondary flow passage outside the membranes, wherein the culture solution supplied from the tank is supplied to the primary flow passage and a permeated liquid containing the product permeate through the secondary flow passage to separate the cells and the product, and in the separation step, when a pressure difference between both ends of the primary flow passage during the feeding of the culture solution is ?P [Pa], and a viscosity of the culture solution is ? [Pa·s], ?P/? is 4.9×106 [1/s] or less.

Abstract: Provided is a method for manufacturing a product, including a culture step of culturing cells, and a separation step of using a hollow fiber membrane filter which has a hollow fiber membrane having a primary flow passage extending and has a housing accommodating a plurality of the hollow fiber membranes, the hollow fiber membrane filter having a secondary flow passage, wherein the culture solution to the primary flow passage and a permeated liquid containing the product permeate through the secondary flow passage to separate the cells and the product, and in the separation step, when a pressure difference between both ends of the primary flow passage during the feeding of the culture solution is ?P [Pa], a membrane resistance of the hollow fiber membrane is r, and a flow passage resistance of the secondary flow passage is R, ?P/2(r+R) is 0.0005 mL/min or less.

Abstract: Provided is a seat having improved rigidity. The seat includes: a first side frame; a second side frame, a connection body; a base member; a first drive-side link; a second drive-side link, an actuator that generates a force for changing an angle between the first drive-side link and the second drive-side link; a first driven-side link that is fixed on the second side frame side of the connection body and rotates integrally with the connection body; a second driven-side link whose first end side is rotatably connected to a second end side of the first driven-side link and whose second end side is rotatably connected to a base member; and a transmission mechanism that mechanically transmits, when a force for rotating the second driven-side link about a connection part between the second driven-side link and the base member acts on the second driven-side link, the force to the connection body.

Abstract: A wireless communication system, a repeater, and a wireless communication method capable of transmitting a message to another user in a specific area selected by a user are provided. The wireless communication system includes a plurality of wireless communication terminals and the repeater. The wireless communication terminal acquires an operation of a user, and transmits a message and direction information. The repeater determines a communication area based on the received information, and transmits a message to another wireless communication terminal worn by a user in the communication area.

Abstract: A sliding device that slidably supports a seat body of a vehicle seat is provided. The sliding device includes: a fixed rail; a movable rail; a locking member displaceable between a locking position and an unlocking position, a sliding movement of the movable rail being restricted in the locking position, and restriction of the sliding movement being released in the unlocking position; a retention spring configured to apply to the locking member a retaining force to retain the locking member in the locking position; a release lever configured to displace the locking member to the unlocking position; a return spring configured to apply to the release lever an elastic force to return the release lever to its initial position; and a restrictor configured to restrict a displacement of the release lever.

Abstract: A wireless communication system, a repeater, and a wireless communication method capable of transmitting a message to another user in a specific area selected by a user are provided. The wireless communication system includes a plurality of wireless communication terminals and the repeater. The wireless communication terminal acquires an operation of a user, and transmits a message and direction information. The repeater determines a communication area based on the received information, and transmits a message to another wireless communication terminal worn by a user in the communication area.

Abstract: A seat sliding device includes: a lower rail; an upper rail; a lock member; a spring member; and an operation lever, the first fixing portion of the spring member which has a ring shape having an outside diameter greater than a width between the pair of the side walls of the upper rail, which has a spring force in a diameter increasing direction between the pair of the side walls of the upper rail, and which includes a first mounting portion and a second mounting portion that are configured to be mounted and fixed, respectively, in the first hole portion and the second hole portion by the spring force.

Abstract: An object to be achieved by the present invention is to provide a culture method for cells, which makes it possible to suppress oxygen deficiency of cells in a case where the cell is cultured at a high density, and a production method for a useful substance using the culture method for cells. According to the present invention, there is provided a culture method for cells, in which a relationship between a stirring power P/V per unit volume, a dissolved oxygen concentration CL0, and a viable cell density VCD satisfies a condition of Expression 1, in cell culture in which the viable cell density is 60×106 cells/mL or more. 0.0059×exp[0.0243×(P/V)]×CL0/VCD?1.10×10?17 ??Expression 1: In the expression, L0 indicates a dissolved oxygen concentration [mol/mL]; VCD indicates a viable cell density [cells/mL]; and P/V indicates a stirring power [W/m3] per unit volume, which is defined by a predetermined expression.

Abstract: The present disclosure discloses one example of a one-way coupling that eliminates the need for a component corresponding to a guide piece. The one-way coupling of the present discloser includes an input shaft and an output shaft, and is configured to transmit a drive force from the input shaft to the output shaft, and inhibit the drive force inputted to the output shaft from being transmitted to the input shaft. The one-way coupling includes: a transmitter; an immovable ring; a pressure-contact cam; a first wedge member displaceable between a locked position and an unlocked position, and receiving a pressing force from the pressure-contact cam when the drive force is inputted to the input shaft, and thereby the first wedge member is displaced to the locked position; and a first holder holding an arrangement of the first wedge member when the drive force is inputted to the output shaft.

Abstract: The present disclosure discloses one example of a one-way coupling that eliminates the need for a component corresponding to a guide piece. The one-way coupling of the present discloser includes an input shaft and an output shaft, and is configured to transmit a drive force from the input shaft to the output shaft, and inhibit the drive force inputted to the output shaft from being transmitted to the input shaft. The one-way coupling includes: a transmitter; an immovable ring; a pressure-contact cam; a first wedge member displaceable between a locked position and an unlocked position, and receiving a pressing force from the pressure-contact cam when the drive force is inputted to the input shaft, and thereby the first wedge member is displaced to the locked position; and a first holder holding an arrangement of the first wedge member when the drive force is inputted to the output shaft.

Abstract: A cell culture device (1) includes: a culture vessel (10 ) that accommodates a cell suspension containing cells and a culture medium; and a stirring device (30) that is provided at a bottom part of the culture vessel (10) to stir the cell suspension accommodated in the culture vessel (10). The stirring device (30) has a shaft part (32), and a rotating part (33) rotatable with the shaft part (32) as a rotation axis. The rotating part (33) has a hole part (36) into which the shaft part (32) is inserted, and a gap (37) of 100 ?m or more is secured between an interior wall demarcating the hole part (36) and the shaft part (32). A closing part (38) that closes an end part of the gap (37) in an axial direction of the rotation axis is provided.

Abstract: A seat sliding device includes: a lower rail; an upper rail; a lock member; a spring member; and an operation lever, the first fixing portion of the spring member which has a ring shape having an outside diameter greater than a width between the pair of the side walls of the upper rail, which has a spring force in a diameter increasing direction between the pair of the side walls of the upper rail, and which includes a first mounting portion and a second mounting portion that are configured to be mounted and fixed, respectively, in the first hole portion and the second hole portion by the spring force.

Abstract: A sliding device that slidably supports a seat body of a vehicle seat is provided. The sliding device includes: a fixed rail; a movable rail; a locking member displaceable between a locking position and an unlocking position, a sliding movement of the movable rail being restricted in the locking position, and restriction of the sliding movement being released in the unlocking position; a retention spring configured to apply to the locking member a retaining force to retain the locking member in the locking position; a release lever configured to displace the locking member to the unlocking position; a return spring configured to apply to the release lever an elastic force to return the release lever to its initial position; and a restrictor configured to restrict a displacement of the release lever.

Abstract: A sliding device includes a fixed rail, a movable rail, a lock plate, a spring member, and a first stopper and a second stopper provided on the lock plate. The lock plate is held by the movable rail, and is displaceable between a locking position where the lock plate engages with the fixed rail and a non-locking position where the engagement is released. The spring member can exert an elastic force to maintain the lock plate in the locking position. The first stopper locks and fixes a first end of the lock plate to the spring member. The second stopper locks and fixes a second end of the lock plate to the spring member.

Abstract: A sliding device includes a fixed rail, a movable rail, a lock plate, and a spring member. A seat body is fixed to the movable rail, and the movable rail is slidable relative to the fixed rail. The lock plate is held by the movable rail, and is displaceable between a locking position where the lock plate engages with the fixed rail and restricts slide of the movable rail and a non-locking position where the restriction is released. The spring member exerts an elastic force to maintain the lock plate in the locking position.

Abstract: A sliding device includes a fixed rail, a movable rail, a lock plate, a spring member, and a fixing structure. The lock plate is displaced between a locking position where the lock plate engages with the fixed rail and restricts slide of the movable rail and a non-locking position where the restriction of slide is released. The spring member exerts an elastic force to maintain the lock plate in the locking position. The fixing structure includes a tapered portion of the spring member and a press spring portion that presses the tapered portion toward a hole of the movable rail.

Abstract: Provide are a cell culture method which includes using a culture vessel which contains a cell suspension containing cells and discharging a gas including 30% by volume or more of oxygen into the cell suspension from a sparger disposed in the culture vessel to culture the cells, in which an average hole diameter in a gas discharge portion in the sparger is 1 ?m or more and 300 ?m or less, and a surface area A (m2) in the gas discharge portion in the sparger, a volume X (m3) of the cell suspension in the culture vessel, and a flow rate Q (m3/min) of the gas that is discharged from the sparger satisfy a specific relationship, a product producing method including the cell culture method, and a cell culture device that enables the cell culture method.

Abstract: A sliding device includes a fixed rail, a movable rail, a lock plate, a spring member, and a first stopper and a second stopper provided on the lock plate. The lock plate is held by the movable rail, and is displaceable between a locking position where the lock plate engages with the fixed rail and a non-locking position where the engagement is released. The spring member can exert an elastic force to maintain the lock plate in the locking position. The first stopper locks and fixes a first end of the lock plate to the spring member. The second stopper locks and fixes a second end of the lock plate to the spring member.