Patents by Inventor Kotamraju Srigiridhar

Kotamraju Srigiridhar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antioxidant compound having anti atherosclerotic effect and preparation thereof
    Patent number: 9963476
    Abstract: The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE?/? mice along with the endothelial cell age-delaying effects of Mito-Esc.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: May 8, 2018
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kotamraju Srigiridhar, Karnewar Santosh, Vasamsetti Sathish Babu, Togapur Pavan Kumar, Basi Venkata Subba Reddy, Jerald Mahesh Kumar
  • ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF
    Publication number: 20170240577
    Abstract: The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE?/? mice along with the endothelial cell age-delaying effects of Mito-Esc.
    Type: Application
    Filed: February 27, 2017
    Publication date: August 24, 2017
    Inventors: Kotamraju Srigiridhar, Karnewar Santosh, Vasamsetti Sathish Babu, Togapur Pavan Kumar, Basi Venkata Subba Reddy, Jerald Mahesh Kumar
  • Antioxidant compound having anti atherosclerotic effect and preparation thereof
    Patent number: 9580452
    Abstract: The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE?/?) mice along with the endothelial cell age-delaying effects of Mito-Esc.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 28, 2017
    Assignee: Council of Scientific and Industrial Research
    Inventors: Kotamraju Srigiridhar, Karnewar Santosh, Vasamsetti Sathish Babu, Togapur Pavan Kumar, Basi Venkata Subba Reddy, Jerald Mahesh Kumar
  • ANTIOXIDANT COMPOUND HAVING ANTI ATHEROSCLEROTIC EFFECT AND PREPARATION THEREOF
    Publication number: 20160244470
    Abstract: The present invention relates to an antioxidant compound having anti atherosclerotic effect and preparation thereof. The present invention more particularly relates to the synthesis of TPP+ coupled esculetin (mitochondria-targeted esculetin [Mito-Esc]) followed by the biological evaluation of Mito-Esc for its ability to attenuate Angiotensin-II-induced atherosclerosis in apolipoproteinE knockout (ApoE?/?) mice along with the endothelial cell age-delaying effects of Mito-Esc.
    Type: Application
    Filed: February 19, 2016
    Publication date: August 25, 2016
    Inventors: Kotamraju Srigiridhar, Karnewar Santosh, Vasamsetti Sathish Babu, Togapur Pavan Kumar, Basi Venkata Subba Reddy, Jerald Mahesh Kumar