Patents by Inventor Kotaro Kodama

Kotaro Kodama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210123919
    Abstract: Biomarkers are provided that are predictive of a subject's responsiveness to a combination therapy comprising lenvatinib compound and a PD-1 antagonist. The biomarkers, compositions, and methods described herein are useful in selecting appropriate treatment modalities for a subject having, suspected of having, or at risk of developing cancer.
    Type: Application
    Filed: May 13, 2019
    Publication date: April 29, 2021
    Applicants: Merck Sharp & Dohme Corp., Eisai R&D Management Co., Ltd.
    Inventors: Yasuhiro FUNAHASHI, Kotaro KODAMA, Ryo DAIRIKI, Yukinori MINOSHIMA
  • Patent number: 7781452
    Abstract: A compound represented by the following general formula (1), or a salt or hydrate thereof: [Formula 1] wherein R1 represents a C1-C6 alkyl group or C2-C6 alkynyl group which may be substituted, or a phenyl group which may be substituted, R2 represents a hydrogen atom or a C1-C6 alkyl group, R3 represents methyl or ethyl group, R4 represents a C1-C6 alkyl group, R5 represents a hydrogen atom, provided that a compound wherein R1 is a C1-C6 alkyl group unsubstituted or substituted with a halogen atom and R2 is a hydrogen atom is excluded.
    Type: Grant
    Filed: March 22, 2006
    Date of Patent: August 24, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Shuhei Miyazawa, Hitoshi Harada, Hideaki Fujisaki, Atsuhiko Kubota, Kotaro Kodama, Junichi Nagakawa, Kiyoshi Oketani, Nobuhisa Watanabe
  • Publication number: 20060167041
    Abstract: A compound represented by the following general formula (1), or a salt or hydrate thereof: [Formula 1] wherein R1 represents a C1-C6 alkyl group or C2-C6 alkynyl group which may be substituted, or a phenyl group which may be substituted, R2 represents a hydrogen atom or a C1-C6 alkyl group, R3 represents methyl or ethyl group, R4 represents a C1-C6 alkyl group, R5 represents a hydrogen atom, provided that a compound wherein R1 is a C1-C6 alkyl group unsubstituted or substituted with a halogen atom and R2 is a hydrogen atom is excluded.
    Type: Application
    Filed: March 22, 2006
    Publication date: July 27, 2006
    Inventors: Shuhei Miyazawa, Hitoshi Harada, Hideaki Fujisaki, Atsuhiko Kubota, Kotaro Kodama, Junichi Nagakawa, Kiyoshi Oketani, Nobuhisa Watanabe
  • Publication number: 20050272764
    Abstract: A compound represented by the following general formula (1), or a salt or hydrate thereof: wherein R1 represents a C1-C6 alkyl group or C2-C6 alkynyl group which may be substituted, or a phenyl group which may be substituted, R2 represents a hydrogen atom or a C1-C6 alkyl group, R3 represents methyl or ethyl group, R4 represents a C1-C6 alkyl group, R5 represents a hydrogen atom, provided that a compound wherein R1 is a C1-C6 alkyl group unsubstituted or substituted with a halogen atom and R2 is a hydrogen atom is excluded.
    Type: Application
    Filed: April 21, 2005
    Publication date: December 8, 2005
    Inventors: Shuhei Miyazawa, Hitoshi Harada, Hideaki Fujisaki, Atsuhiko Kubota, Kotaro Kodama, Junichi Nagakawa, Kiyoshi Oketani, Nobuhisa Watanabe