Abstract: An information processing apparatus configured to determine a tour schedule around a facility, the information processing apparatus includes a controller configured to determine a tour time at a tour spot in the tour schedule, based on biological information on a user who is observing a process performed by equipment at the tour spot in the facility.

Abstract: An object of the present invention is to provide a pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof at a high concentration, with a characteristic bitter taste masked, and a manufacturing method thereof. The present invention provides a pharmaceutical composition comprising fine granules having a core comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof, and a binder; and a polymer layer with which a surface of the core is coated, wherein the fine granules have a roundness of 0.8 or more and a content of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or the salt thereof in the fine granules is 30 to 90% by mass.

Abstract: An object of the present invention is to provide a solid pharmaceutical composition which suppresses the characteristic bitter taste of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and has a good storage stability of the-aforementioned compound or a salt thereof. The present invention provides a solid pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and a carboxylic acid whose solubility in water at 25° C. is 50 g/100 g H2O or less, wherein pH of a solution obtained when the solid pharmaceutical composition is dissolved or suspended in a 10 mmol/L KCl solution such that 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or the salt thereof is 1 mg/mL or 8.96 mg/mL is 4.8 or less.

Abstract: An object of the present invention is to provide a pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof at a high concentration, with a characteristic bitter taste masked, and a manufacturing method thereof. The present invention provides a pharmaceutical composition comprising fine granules having a core comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof, and a binder; and a polymer layer with which a surface of the core is coated, wherein the fine granules have a roundness of 0.8 or more and a content of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or the salt thereof in the fine granules is 30 to 90% by mass.

Abstract: An object of the present invention is to provide a solid pharmaceutical composition which suppresses the characteristic bitter taste of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and has a good storage stability of the-aforementioned compound or a salt thereof. The present invention provides a solid pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and a carboxylic acid whose solubility in water at 25° C. is 50 g/100 g H2O or less, wherein pH of a solution obtained when the solid pharmaceutical composition is dissolved or suspended in a 10 mmol/L KCl solution such that 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or the salt thereof is 1 mg/mL or 8.96 mg/mL is 4.8 or less.

Abstract: The object of the present invention is to provide a solid pharmaceutical composition in which both the pre-bitter taste and the post-bitter taste of 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof are suppressed. The present invention provides a solid pharmaceutical composition comprising 1-(3-(2-(1-benzothiophen-5-yl)ethoxy)propyl)azetidin-3-ol or a salt thereof and a compound having at least one hydrocarbon group having 8 to 18 carbon atoms and a sulfo group or a salt thereof.

Abstract: A vehicle steering device includes: a target-steered-angle setting unit configured to set a left target steered angle that is a target value of the steered angle of a left steered wheel and a right target steered angle that is a target value of the steered angle of a right steered wheel; left motor controllers configured to control a left steering motor based on a left-steered-angle deviation that is a difference between the left steered angle and the left target steered angle; right motor controllers configured to control a right steering motor based on a right-steered-angle deviation that is a difference between the right steered angle and the right target steered angle; and an abnormality determination unit configured to determine that an abnormality has occurred when an absolute value of difference between the left-steered-angle deviation and the right-steered-angle deviation is equal to or larger than a first threshold.

Abstract: An orally disintegrating tablet including: fine granules, each fine granule having, at its center, an active pharmaceutical ingredient-containing core that includes butylscopolamine bromide and water-insoluble particles, and having an intermediate layer that includes water-insoluble particles and coats the active pharmaceutical ingredient-containing core, and a bitterness-masking layer that includes talc and at least one water-insoluble polymer, in sequence from the active pharmaceutical ingredient-containing core side; and an excipient component positioned on the outside of the fine granules, and a method for producing the same.

Abstract: A vehicle steering device includes: a target-steered-angle setting unit configured to set a left target steered angle that is a target value of the steered angle of a left steered wheel and a right target steered angle that is a target value of the steered angle of a right steered wheel; left motor controllers configured to control a left steering motor based on a left-steered-angle deviation that is a difference between the left steered angle and the left target steered angle; right motor controllers configured to control a right steering motor based on a right-steered-angle deviation that is a difference between the right steered angle and the right target steered angle; and an abnormality determination unit configured to determine that an abnormality has occurred when an absolute value of difference between the left-steered-angle deviation and the right-steered-angle deviation is equal to or larger than a first threshold.

Abstract: A predriver circuit that is capable of reducing the size of a drive transistor while preventing a drive transistor's gate from being destroyed, thereby reducing power consumption. The predriver circuit includes a current mirror circuit, which has a pair of transistors that are connected to a predriver power supply voltage; a level shifter circuit, which is connected to a first transistor via a self-bias circuit; and a discharge transistor, which is connected to a second transistor. A terminal connecting the second transistor to the discharge transistor is connected to a top gate of a high-side MOS transistor for a half-bridge connected drive circuit.

Abstract: A predriver circuit that is capable of reducing the size of a drive transistor while preventing a drive transistor's gate from being destroyed, thereby reducing power consumption. The predriver circuit includes a current mirror circuit, which has a pair of transistors that are connected to a predriver power supply voltage; a level shifter circuit, which is connected to a first transistor via a self-bias circuit; and a discharge transistor, which is connected to a second transistor. A terminal connecting the second transistor to the discharge transistor is connected to a top gate of a high-side MOS transistor for a half-bridge connected drive circuit.

Abstract: A voltage converting circuit receiving an input voltage and an increased voltage and providing an output voltage higher than the input voltage at an output terminal, comprises a first pair of gate devices serially connected between the input voltage and a ground, a second pair of gate devices serially connected between the input voltage and the output terminal, a first capacitor connected between a node between the first pair of gate devices and a node between the second pair of gate devices for boosting the output voltage, a second capacitor connected between the output terminal and the ground for smoothing the output voltage, a control circuit for controlling said pairs of gate devices, and a pair of drivers for driving the second pair of gate devices respectively under the control of the control circuit. The pair of drivers are connected so as to operate between the increased voltage and the input voltage.

Abstract: A voice coil motor driving circuit 10 with retracting function used in a disk drive unit for driving a read/write head by means of a voice coil motor VCM, comprising a voltage up-converter 12; a voice coil motor control circuit 16 for driving the voice coil motor during normal operation; a retract power source Vrr for supplying a retract current to the voice coil motor during head retract action; a retract control circuit 24 for allowing the retract current from the retract power source to the voice coil motor in response to a retract signal. The driving circuit also includes a capacitor C for providing an uninterrupted supply of voltage to the retract control circuit 24 during head retract action.

Abstract: A voltage converter for stably converting, even a low input voltage, to a predetermined output level is provided. The output of cell 20 is increased by first and second step-up circuits 21 and 22, and then smoothed by smoothing circuit 31. The output is converted by the first step-up circuit from the start of voltage conversion until a predetermined output voltage, and then converted by the second step-up converter thereafter. The output voltage of smoothing circuit 31 is compared against a first reference voltage by first comparator circuit 35, the output of which activates the integral circuit in second comparator circuit 37. The charge voltage of the integral circuit is compared to a sawtooth wave STW generated by oscillator circuit 43 to derive a signal for forcefully shutting down MOS transistor 29 in the second step-up circuit.

Abstract: A DC/DC voltage converting device is obtained for boosting a DC power supply voltage to provide a higher output voltage, comprising soft start circuit 20 for gradually increasing the turning-on duration of transistor 34 in boosting circuit 30; pulse width control circuit 60 for providing a modulated pulse signal P2 to control the boosted voltage. The device further comprises boosting circuit 30 including an inductor 32, diode 36 and transistor 34. Boosting circuit 30 provides a predetermined boosted voltage higher than the power supply voltage by alternately turning on and off transistor 34. The turning-on duration of transistor 34 is gradually increased during the initial operation period by soft start circuit 20, and is controlled by modulated pulse signal P2 during a stable operation period. The device further comprises gate circuit 40 having diode 46 and transistor 44, and step up circuit 70.

Abstract: An apparatus for securing a sheet material under suction, the apparatus comprising: a face plate including a number of pores adapted to allow air to pass through, a base plate including outlet ports, corrugated plate interlocated between the face plate and the base plate, the corrugated plate including hill portions and valley portions alternately produced, each hill portion and valley portion taking the form of rectangles produced concentrically of the base plate, the corrugated plate further including inlet grooves between one hill portion and the next, and outlet grooves between one valley portion and the next, each outlet groove including one outlet port in the base plate, the inlet grooves and the outlet grooves being communicated with each other through a port produced in the partition wherein the port is located at a point distant from the outlet ports.