Patents by Inventor Koteswar Yeleswarapu

Koteswar Yeleswarapu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20070122444
    Abstract: The present invention relates to methods, compounds, and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses, and is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention also relates to compounds that inhibit smooth muscle proliferation, for example, by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis. This invention also relates to medical devices, such as a stent, comprising a compound or composition of this invention disposed on or within the medical device.
    Type: Application
    Filed: August 30, 2006
    Publication date: May 31, 2007
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Rama Murali Krishna Reddy, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20070117795
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: August 28, 2006
    Publication date: May 24, 2007
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Krishna Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20070099874
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: March 26, 2003
    Publication date: May 3, 2007
    Applicant: Reddy US Therapeutics, Inc.
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20070004729
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: June 20, 2006
    Publication date: January 4, 2007
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Methods and compositions of novel triazine compounds
    Publication number: 20060258641
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: May 25, 2006
    Publication date: November 16, 2006
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Rama Reddy, Sesha Alluri, Potlapally Kumar, Gaddam Reddy
  • Novel pyrimidine compounds, process for their preparation and compositions containing them
    Publication number: 20060084645
    Abstract: The present invention provides new heterocyclic compounds, particularly substituted pyrimidines, methods and compositions for making and using these heterocyclic compounds, and methods for treating a variety of diseases and disease states, including atherosclerosis, arthritis, restenosis, diabetic nephropathy, or dyslipidemia, or disease states mediated by the low expression of Perlecan.
    Type: Application
    Filed: September 23, 2005
    Publication date: April 20, 2006
    Inventors: Manojit Pal, Srinivas Kalleda, Srinivas Padakanti, Nalivela Swamy, Koteswar Yeleswarapu, Christopher Alexander, Ish Khanna, Javed Iqbal, Sivaram Pillarisetti, Deepak Barange
  • Triazine compounds and their analogs, compositions, and methods
    Publication number: 20050227983
    Abstract: The present invention relates to triazine compounds and their analogs and derivatives, and methods and compositions comprising these compounds. The compounds and compositions of this invention are useful for, among other things, treating pathophysiological conditions arising from inflammatory responses, inhibiting or blocking glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells, inhibiting smooth muscle proliferation, treating vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis, and the like.
    Type: Application
    Filed: March 24, 2004
    Publication date: October 13, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Sesha Alluri, Velagala Venkata Krishna Reddy, Manojit Pal, Jangalgar Reddy, Koteswar Yeleswarapu, Gaddam Reddy, Potlapally Kumar
  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20050137196
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 23, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krishna Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20050124619
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: September 27, 2004
    Publication date: June 9, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Venkata Krisha Reddy, Bhatlapenumarthy Sesha Sridevi, Potlapally Kumar, Gaddam Reddy
  • Medical devices employing triazine compounds and compositions thereof
    Publication number: 20050113341
    Abstract: The present invention relates to methods and compositions comprising compounds that treat pathophysiological conditions arising from inflammatory responses. In particular, the present invention is directed to compounds that inhibit or block glycated protein produced induction of the signaling-associated inflammatory response in endothelial cells. The present invention relates to compounds that inhibit smooth muscle proliferation. In particular, the present invention is directed to compounds that inhibit smooth muscle cell proliferation by modulating HSPGs such as Perlecan. The present invention further relates to the use of compounds to treat vascular occlusive conditions characterized by smooth muscle proliferation such as restenosis and atherosclerosis.
    Type: Application
    Filed: September 27, 2004
    Publication date: May 26, 2005
    Inventors: Richard Timmer, Christopher Alexander, Sivaram Pillarisetti, Uday Saxena, Koteswar Yeleswarapu, Manojit Pal, Jangalgar Reddy, Velagala Murali Krishna Reddy, Bhatlapenumarthy Sridevi, Potlapally Kumar, Gaddam Reddy