Patents by Inventor Koteswara Rao Valasani

Koteswara Rao Valasani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease
    Patent number: 9738668
    Abstract: Benzothiazole phosphonate analogs and methods of using the same to inhibit the activity of Amyloid Binding Alcohol Dehydrogenase and in the amelioration or treatment of Alzheimer's disease are provided.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: August 22, 2017
    Assignee: University of Kansas
    Inventors: ShiDu Yan, Koteswara Rao Valasani
  • Cyclophilin D inhibitors
    Patent number: 9738615
    Abstract: A compound that can function as a Cyclophilin D can include a structure of Formula 1 or Formula 2 or Formula 3 or Formula 4 or Formula 5 or Formula 6 or Formula 7 or Formula 8, derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof, as presented herein. The Cyclophilin D inhibitors can inhibit onset or treat neurodegenerative disease, such as Alzheimer's disease, or can be used for inhibiting progression or treating diabetes.
    Type: Grant
    Filed: September 11, 2015
    Date of Patent: August 22, 2017
    Assignee: The University of Kansas
    Inventors: Shirley ShiDu Yan, Koteswara Rao Valasani
  • PHOSPHONATE DERIVATIVES AND METHODS OF USE THEREOF IN THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20160263133
    Abstract: Benzothiazole phosphonate analogs and methods of using the same to inhibit the activity of Amyloid Binding Alcohol Dehydrogenase and in the amelioration or treatment of Alzheimer's disease are provided.
    Type: Application
    Filed: May 24, 2016
    Publication date: September 15, 2016
    Inventors: ShiDu Yan, Koteswara Rao Valasani
  • Phosphonate derivatives and methods of use thereof in the treatment of Alzheimer's disease
    Patent number: 9346839
    Abstract: Benzothiazole phosphonate analogs and methods of using the same to inhibit the activity of Amyloid Binding Alcohol Dehydrogenase and in the amelioration or treatment of Alzheimer's disease are provided.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: May 24, 2016
    Assignee: University of Kansas
    Inventors: ShiDu Yan, Koteswara Rao Valasani
  • CYCLOPHILIN D INHIBITORS
    Publication number: 20160075669
    Abstract: A compound that can function as a Cyclophilin D can include a structure of Formula 1 or Formula 2 or Formula 3 or Formula 4 or Formula 5 or Formula 6 or Formula 7 or Formula 8, derivative thereof, prodrug thereof, salt thereof, or stereoisomer thereof, or having any chirality at any chiral center, or tautomer, polymorph, solvate, or combination thereof, as presented herein. The Cyclophilin D inhibitors can inhibit onset or treat neurodegenerative disease, such as Alzheimer's disease, or can be used for inhibiting progression or treating diabetes.
    Type: Application
    Filed: September 11, 2015
    Publication date: March 17, 2016
    Inventors: Shirley ShiDu Yan, Koteswara Rao Valasani
  • PHOSPHONATE DERIVATIVES AND METHODS OF USE THEREOF IN THE TREATMENT OF ALZHEIMER'S DISEASE
    Publication number: 20150065463
    Abstract: Benzothiazole phosphonate analogs and methods of using the same to inhibit the activity of Amyloid Binding Alcohol Dehydrogenase and in the amelioration or treatment of Alzheimer's disease are provided.
    Type: Application
    Filed: November 12, 2014
    Publication date: March 5, 2015
    Applicant: University of Kansas
    Inventors: ShiDu Yan, Koteswara Rao Valasani