Patents by Inventor Kotha J. Subbaramaiah

Kotha J. Subbaramaiah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of screening agents as candidates for drugs or sources of drugs
    Patent number: 6200760
    Abstract: Cells are transfected with a construct containing transcriptional promoter element(s) that have been implicated in carcinogenesis or inflammation ligated to a reporter gene. Determination of inhibition of activation of said promoter element(s) by putative agent indicates the agent is a candidate as a drug or source of a drug for prophylaxis or treatment of cancer or inflammation. The method has particular application to screening agents as candidates for drugs or sources of drugs for prophylaxis or treatment of human disorders caused or mediated by cyclooxygenase-2 and/or matrix metalloproteinases.
    Type: Grant
    Filed: August 13, 1999
    Date of Patent: March 13, 2001
    Assignees: Cornell Research Foundation, Inc., The University of Mississippi
    Inventors: Andrew J. Dannenberg, Kotha J. Subbaramaiah, David S. Pasco