Patents by Inventor Kouhei Furuya

Kouhei Furuya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated cultures of Pestalotiopsis funerea IFO 5427 and Pestalotiopsis negleta FERM BP-3501
    Patent number: 5604128
    Abstract: Isolated cultures of Pestalotiopsis funerea IFO 5427 and Pestalotiopsis neglecta FERM BP-3501 are provided. The cultures produce a glucoamylase which digests starch.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 18, 1997
    Assignee: Sankyo Company, Limited
    Inventors: Atsushi Hattori, Masami Miura, Mitsuyo Takahashi, Noriyoshi Uchida, Kouhei Furuya, Tsuyoshi Hosoya
  • Isolated cultures of microorganisms of Clonostachys Cylindrospora, Gliocladium and Nectria Gliocladioides
    Patent number: 5407826
    Abstract: Trans-4-hydroxy-L-proline is produced microbially, especially by the cultivation of a microorganism of the genus Clonostachys, Gliocladium or Nectria.
    Type: Grant
    Filed: March 22, 1994
    Date of Patent: April 18, 1995
    Assignee: Sankyo Company, Limited
    Inventors: Tatsuji Matsuoka, Nobufusa Serizawa, Tsuyoshi Hosoya, Kouhei Furuya
  • Microbial process for the production of trans-4-hydroxy-L-proline
    Patent number: 5334517
    Abstract: Trans-4-hydroxy-L-proline is produced microbially, especially by the cultivation of a microorganism of the genus Clonostachys, Gliocladium or Nectria.
    Type: Grant
    Filed: December 15, 1992
    Date of Patent: August 2, 1994
    Assignee: Sankyo Company Limited
    Inventors: Tatsuji Matsuoka, Nobufusa Serizawa, Tsuyoshi Hosoya, Kouhei Furuya
  • Platelet activating factor antagonists, named "the phomactins", their preparation and use
    Patent number: 5308867
    Abstract: A series of new compounds, called "the phomactins" is provided and may be isolated from the culture broth of fungi of the genus Phoma. especially Phomas sp. SANK 11486 (No. FERM BP-2598). These compounds are platelet activating factor antagonists and may be used for the treatment of disorders for which known such agents may also be used.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: May 3, 1994
    Assignee: Sankyo Company, Limited
    Inventors: Aiya Sato, Michihiro Sugano, Kouhei Furuya, Takeshi Oshima, Harumitsu Kuwano, Tadashi Hata, Hideyuki Haruyama
  • Hydroxy-ML-236B derivatives, their preparation and use
    Patent number: 5272174
    Abstract: Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be prepared by the enzymatic hydroxylation of a corresponding ML-236B compound employing an enzyme produced by a microorganism of the genus Streptomyces or Amycolata, especially Streptomyces sp. SANK 62285, Streptomyces sp. SANK 62385, Streptomyces sp. SANK 62485, Streptomyces sp. SANK 62585, Amycolata autotrophica SANK 62781. Amycolata autotrophica subsp. canberrica SANK 62882 or Amycolata autotrophica subsp. amethystina SANK 62981. These derivatives have the ability to inhibit cholesterol biosynthesis.
    Type: Grant
    Filed: July 23, 1992
    Date of Patent: December 21, 1993
    Assignee: Sankyo Company, Limited
    Inventors: Kouhei Furuya, Takao Okazaki, Yoshio Tsujita, Seigo Iwado, Kiyoshi Hamano, Masao Kuroda, Jun Yoshikawa, Toshiaki Iwai, Kunio Nakano
  • Hydroxyl-ML-236B derivatives, their preparation and use
    Patent number: 5153124
    Abstract: Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be prepared by the enzymatic hydroxylation of a corresponding ML-236B compound employing an enzyme produced by a microorganism of the genus Streptomyces or Amycolata, especially Streptomyces sp. SANK 62285, Streptomyces sp. SANK 62385, Streptomyces sp. SANK 62485, Streptomyces sp. SANK 62585, Amycolata autotrophica SANK 62781, Amycolata autotrophica subsp. canberrica SANK 62882 or Amycolata autotrophica subsp. amethystina SANK 62981. These derivatives have the ability to inhibit cholesterol biosynthesis.
    Type: Grant
    Filed: August 11, 1989
    Date of Patent: October 6, 1992
    Assignee: Sankyo Company Limited
    Inventors: Kouhei Furuya, Takao Okazaki, Yoshio Tsujita, Seigo Iwado, Kiyoshi Hamano, Masao Kuroda, Jun Yoshikawa, Toshiaki Iwai, Kunio Nakano
  • Platelet activating factor antagonists, named "the phomactins" their preparation and use
    Patent number: 5151529
    Abstract: A series of new compounds, called "the phomactins" is provided and may be isolated from the culture broth of fungi of the genus Phoma, especially Phoma sp. SANK 11486 (No. FERM BP-2598). These compounds are platelet activating factor antagonists and may be used for the treatment of disorders for which known such agents may also be used.
    Type: Grant
    Filed: October 10, 1990
    Date of Patent: September 29, 1992
    Assignee: Sankyo Company, Limited
    Inventors: Aiya Sato, Michihiro Sugano, Kouhei Furuya, Takeshi Oshima, Harumitsu Kuwano, Tadashi Hata, Hideyuki Haruyama
  • Compound "Leualacin", its preparation and its use in the treatment of cardiovascular disorders
    Patent number: 5112807
    Abstract: A new compound, which we have named "Leualacin" has the formula (I): ##STR1## and may be prepared by cultivation of a microorganism of the genus Hapsidospora, especially Hapsidospora irregularis. The compound may be used for the treatment and prophylaxis of cardiovascular diseases and disorders, especially hypertension.
    Type: Grant
    Filed: September 5, 1989
    Date of Patent: May 12, 1992
    Assignee: Sankyo Company, Limited
    Inventors: Kiyoshi Hamano, Kouhei Furuya, Kazuhiko Tanzawa, Takeshi Kagasaki, Masaaki Miyamoto, Takeshi Kinoshita
  • Preparation of Monacolin K
    Patent number: 4323648
    Abstract: Monacolin K, which is an antihypercholesteraemic agent of molecular formula C.sub.24 H.sub.36 O.sub.5, is prepared by cultivating one or more of the microorganisms Monascus anka SANK 10171 (IFO 6540), Monascus purpureus SANK 10271 (IFO 4513), Monascus ruber SANK 10671 (FERM 4958), Monascus vitreus SANK 10960 (FERM 4960), Monascus paxii SANK 11172 (IFO 8201), Monascus ruber SANK 13778 (FERM 4959), Monascus ruber SANK 15177 (FERM 4956) or Monascus ruber SANK 18174 (FERM 4957) in a suitable culture medium and then isolating the Monacolin K from the resulting culture broth.
    Type: Grant
    Filed: April 4, 1980
    Date of Patent: April 6, 1982
    Assignee: Sankyo Company Limited
    Inventors: Kazuhiko Tanzawa, Seigo Iwado, Yoshio Tsujita, Masao Kuroda, Kouhei Furuya